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| | KRT84 | Keratin 84; Belongs to the intermediate filament family. (593 aa) |
| | FRZB | Frizzled related protein. (325 aa) |
| | SOX9 | SRY-box transcription factor 9. (525 aa) |
| | STAT5B | Signal transducer and activator of transcription. (808 aa) |
| | HOXA7 | Homeobox A7. (239 aa) |
| | HES5 | Hes family bHLH transcription factor 5. (165 aa) |
| | LHX1 | LIM homeobox 1. (406 aa) |
| | S1PR3 | Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (379 aa) |
| | STAT5A | Signal transducer and activator of transcription. (810 aa) |
| | CD109 | CD109 molecule. (1446 aa) |
| | CYP27C1 | Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family. (372 aa) |
| | ZFP36L1 | ZFP36 ring finger protein like 1. (338 aa) |
| | ETV4 | ETS variant 4. (490 aa) |
| | TRIM16 | Uncharacterized protein. (559 aa) |
| | SULT2B1 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (338 aa) |
| | SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (780 aa) |
| | GDNF | Glial cell derived neurotrophic factor. (211 aa) |
| | ZFP36 | ZFP36 ring finger protein. (325 aa) |
| | PAX6 | Paired box 6. (486 aa) |
| | VDR | Vitamin D receptor. (491 aa) |
| | NME2 | Nucleoside diphosphate kinase. (152 aa) |
| | ZDHHC21 | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa) |
| | MACROH2A1 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (371 aa) |
| | F11R | F11 receptor. (298 aa) |
| | NOTCH1 | Notch receptor 1. (2508 aa) |
| | BMP4 | Bone morphogenetic protein 4. (409 aa) |
| | JAG1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa) |
| | FOXJ2 | Forkhead box J2. (561 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa) |
| | SGPP1 | Sphingosine-1-phosphate phosphatase 1. (445 aa) |
| | VEZF1 | Vascular endothelial zinc finger 1. (519 aa) |
| | FOXN1 | Forkhead box N1. (645 aa) |
| | CLDN5 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) |
| | OSR1 | Odd-skipped related transcription factor 1. (267 aa) |
| | ABCA12 | ATP binding cassette subfamily A member 12. (2589 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | PRKX | Uncharacterized protein; Belongs to the protein kinase superfamily. (347 aa) |
| | PROC | Vitamin K-dependent protein C; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family. (458 aa) |
| | ALOX15B | Arachidonate 15-lipoxygenase type B. (677 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa) |
| | GDF2 | Growth differentiation factor 2. (430 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (280 aa) |
| | NCOA3 | Nuclear receptor coactivator. (1471 aa) |
| | PTCH2 | Patched 2. (1207 aa) |
| | GRHL2 | Grainyhead like transcription factor 2. (622 aa) |
| | XDH | FAD-binding PCMH-type domain-containing protein. (1331 aa) |
| | WWTR1 | WW domain containing transcription regulator 1. (419 aa) |
| | MYCL | MYCL proto-oncogene, bHLH transcription factor. (364 aa) |
| | YAP1 | Yes associated protein 1. (503 aa) |
| | MMP9 | Uncharacterized protein. (709 aa) |
| | FST | Uncharacterized protein. (344 aa) |
| | PRKCH | Protein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa) |
| | AJAP1 | Adherens junctions associated protein 1. (416 aa) |
| | ZEB1 | Zinc finger E-box binding homeobox 1. (1127 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | FAT4 | FAT atypical cadherin 4. (4982 aa) |
| | SRSF6 | Uncharacterized protein. (345 aa) |
| | MAFG | MAF bZIP transcription factor G. (162 aa) |
| | CDH5 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (783 aa) |
| | NFE2L1 | Nuclear factor, erythroid 2 like 1. (774 aa) |
| | BAD | BCL2 associated agonist of cell death. (198 aa) |
| | PAX4 | Paired box 4. (372 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | LIF | LIF interleukin 6 family cytokine. (202 aa) |
| | ERRFI1 | ERBB receptor feedback inhibitor 1. (460 aa) |
| | PTCH1 | Patched 1. (1453 aa) |
| | ASCL1 | Achaete-scute family bHLH transcription factor 1. (219 aa) |
| | ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1384 aa) |
| | BMP2 | TGF_BETA_2 domain-containing protein. (381 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (449 aa) |
| | TMEM100 | Transmembrane protein 100. (134 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa) |
| | TBX3 | T-box transcription factor 3. (749 aa) |
| | BTG1 | B-cell translocation protein 1. (171 aa) |
| | KEAP1 | Kelch like ECH associated protein 1. (624 aa) |
| | MAFF | MAF bZIP transcription factor F. (166 aa) |
| | ATOH8 | Atonal bHLH transcription factor 8. (315 aa) |
| | COMMD5 | COMM domain containing 5. (224 aa) |
| | SPRED1 | Sprouty related EVH1 domain containing 1. (433 aa) |
| | TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (640 aa) |
| | ATOH1 | Atonal bHLH transcription factor 1. (352 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa) |
| | FOXJ1 | Forkhead box J1. (421 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | SIX2 | SIX homeobox 2. (296 aa) |
| | CYP27B1 | Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa) |
| | S1PR2 | Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (352 aa) |
| | ENSCHIP00000006081 | Uncharacterized protein. (72 aa) |
| | BMP7 | Bone morphogenetic protein 7. (431 aa) |
| | ENSCHIP00000005003 | Uncharacterized protein. (345 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) |
| | SFRP4 | Secreted frizzled related protein 4. (346 aa) |
| | SPRY2 | Sprouty RTK signaling antagonist 2. (315 aa) |
| | APOLD1 | Apolipoprotein L domain containing 1. (246 aa) |
| | MESP1 | Mesoderm posterior bHLH transcription factor 1. (256 aa) |
| | NUMA1 | Nuclear mitotic apparatus protein 1. (2115 aa) |
| | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa) |
| | KLF7 | Kruppel-like factor 7. (302 aa) |
| | FOXE3 | Forkhead box E3. (315 aa) |
| | NKX6-3 | Homeobox domain-containing protein. (263 aa) |
| | SFN | Stratifin; Belongs to the 14-3-3 family. (248 aa) |
| | ZBED2 | Zinc finger BED-type containing 2. (217 aa) |
| | NODAL | Nodal growth differentiation factor. (346 aa) |
| | VCL | Vinculin. (1134 aa) |
| | MAFK | MAF bZIP transcription factor K. (156 aa) |
| | MACROH2A2 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (681 aa) |
| | KRT36 | Keratin 36; Belongs to the intermediate filament family. (459 aa) |
| | VHL | Uncharacterized protein. (181 aa) |
| | ADD1 | Adducin 1. (736 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1577 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |
| | KDF1 | Keratinocyte differentiation factor 1. (398 aa) |
| | GATA3 | GATA binding protein 3. (467 aa) |
| | ETV2 | ETS domain-containing protein. (153 aa) |
| | NKX2-2 | NK2 homeobox 2. (273 aa) |
| | AHI1 | Abelson helper integration site 1. (1194 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | CEBPB | CCAAT/enhancer-binding protein. (307 aa) |
| | PROM1 | Prominin 1. (855 aa) |
| | BMP6 | Bone morphogenetic protein 6. (496 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | GRHL1 | CP2 domain-containing protein. (617 aa) |
| | HEY2 | Hes related family bHLH transcription factor with YRPW motif 2. (337 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) |
| | ACVRL1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) |
