STRINGSTRING
LOC108638107 LOC108638107 WNT3A WNT3A WNT5A WNT5A LOC102178616 LOC102178616 AREG AREG ENSCHIP00000014888 ENSCHIP00000014888 HIF1A HIF1A EPHA2 EPHA2 IRF6 IRF6 GLI3 GLI3 USF2 USF2 FGF10 FGF10 LOC102184390 LOC102184390 CCL11 CCL11 LOC102190477 LOC102190477 TNFSF11 TNFSF11 MST1 MST1 WNT7B WNT7B TBX2 TBX2 MSX1 MSX1 ESR1 ESR1 PTCH1 PTCH1 CREB1 CREB1 CSF1 CSF1 SOCS2 SOCS2 LATS1 LATS1 CSN3 CSN3 IQGAP3 IQGAP3 CEBPB CEBPB ZBTB7B ZBTB7B ERBB4 ERBB4 STAT6 STAT6 TNFRSF11A TNFRSF11A LEF1 LEF1 ARHGAP35 ARHGAP35 MED1 MED1 ENSCHIP00000028487 ENSCHIP00000028487 RXFP1 RXFP1 VDR VDR LOC102171116 LOC102171116 HOXD9 HOXD9 SMO SMO LOC102180550 LOC102180550 HOXB9 HOXB9 CAPN1 CAPN1 STAT5A STAT5A TPH1 TPH1 ZNF703 ZNF703 NEURL1 NEURL1 CSN2 CSN2 STAT5B STAT5B PRP1 PRP1 SOX9 SOX9 DDR1 DDR1 AR AR SLC6A3 SLC6A3 BMP4 BMP4 GPAT4 GPAT4 NTN1 NTN1 LRRC1 LRRC1 NOTCH4 NOTCH4 KDM5B KDM5B BCL2L11 BCL2L11 LRP5 LRP5 CAV1 CAV1 ORAI1 ORAI1 SCRIB SCRIB CSMD1 CSMD1 FOXF1 FOXF1 WNT3 WNT3 FASN FASN ID2 ID2 FGF2 FGF2 TGFA TGFA CSMD2 CSMD2 NME1 NME1 PHB2 PHB2 MAPK1 MAPK1 NRG3 NRG3 ENSCHIP00000000397 ENSCHIP00000000397 AGAP2 AGAP2 IRS2 IRS2 BSX BSX HOXA9 HOXA9 HOXA5 HOXA5 SRC SRC ENSCHIP00000003193 ENSCHIP00000003193 FOXB1 FOXB1 NFKB1 NFKB1 PML PML CCND1 CCND1 ELF3 ELF3 PRP6 PRP6 WNT2 WNT2 TGFBR2 TGFBR2 TGFB1 TGFB1 TBX3 TBX3 SOSTDC1 SOSTDC1 LOC102170569 LOC102170569 ATP2C2 ATP2C2 BTRC BTRC GHRHR GHRHR ENSCHIP00000016419 ENSCHIP00000016419
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108638107Uncharacterized protein. (238 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
LOC102178616Uncharacterized protein. (265 aa)
AREGAmphiregulin. (264 aa)
ENSCHIP00000014888IRF tryptophan pentad repeat domain-containing protein. (244 aa)
HIF1AUncharacterized protein. (823 aa)
EPHA2EPH receptor A2. (975 aa)
IRF6IRF tryptophan pentad repeat domain-containing protein. (467 aa)
GLI3GLI family zinc finger 3. (1614 aa)
USF2Upstream transcription factor 2, c-fos interacting. (346 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
LOC102184390Uncharacterized protein. (287 aa)
CCL11C-C motif chemokine. (97 aa)
LOC102190477Uncharacterized protein. (238 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (316 aa)
MST1Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (722 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (416 aa)
TBX2T-box transcription factor 2. (771 aa)
MSX1Msh homeobox 1. (303 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (596 aa)
PTCH1Patched 1. (1453 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (554 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
LATS1Large tumor suppressor kinase 1. (1145 aa)
CSN3Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk. (183 aa)
IQGAP3IQ motif containing GTPase activating protein 3. (1635 aa)
CEBPBCCAAT/enhancer-binding protein. (307 aa)
ZBTB7BZinc finger and BTB domain containing 7B. (539 aa)
ERBB4Protein kinase domain-containing protein. (462 aa)
STAT6Signal transducer and activator of transcription. (841 aa)
TNFRSF11ATNF receptor superfamily member 11a. (588 aa)
LEF1HMG box domain-containing protein. (430 aa)
ARHGAP35Rho GTPase activating protein 35. (1500 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1577 aa)
ENSCHIP00000028487Uncharacterized protein. (249 aa)
RXFP1Relaxin family peptide receptor 1. (763 aa)
VDRVitamin D receptor. (491 aa)
LOC102171116Uncharacterized protein. (226 aa)
HOXD9Homeobox D9. (351 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (780 aa)
LOC102180550Uncharacterized protein. (237 aa)
HOXB9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (250 aa)
CAPN1Uncharacterized protein; Belongs to the peptidase C2 family. (744 aa)
STAT5ASignal transducer and activator of transcription. (810 aa)
TPH1Tryptophan hydroxylase 1. (444 aa)
ZNF703Zinc finger protein 703. (588 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (574 aa)
CSN2Beta-casein; Important role in determination of the surface properties of the casein micelles. (228 aa)
STAT5BSignal transducer and activator of transcription. (808 aa)
PRP1Prolactin-related protein-1. (238 aa)
SOX9SRY-box transcription factor 9. (525 aa)
DDR1Tyrosine-protein kinase receptor. (915 aa)
ARAndrogen receptor. (891 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (743 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
GPAT4Glycerol-3-phosphate acyltransferase 4. (456 aa)
NTN1Netrin 1. (496 aa)
LRRC1Leucine rich repeat containing 1. (517 aa)
NOTCH4Notch receptor 4. (1966 aa)
KDM5BLysine demethylase 5B. (1539 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (195 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1615 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (306 aa)
SCRIBScribble planar cell polarity protein. (1582 aa)
CSMD1CUB and Sushi multiple domains 1. (3068 aa)
FOXF1Forkhead box F1. (391 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
FASNFatty acid synthase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein. (2755 aa)
ID2BHLH domain-containing protein. (134 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
TGFATransforming growth factor alpha. (215 aa)
CSMD2CUB and Sushi multiple domains 2. (3313 aa)
NME1Nucleoside diphosphate kinase. (157 aa)
PHB2Prohibitin. (289 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa)
NRG3Uncharacterized protein. (382 aa)
ENSCHIP00000000397Uncharacterized protein. (328 aa)
AGAP2ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1191 aa)
IRS2Insulin receptor substrate 2. (1465 aa)
BSXBrain specific homeobox. (232 aa)
HOXA9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (279 aa)
HOXA5Homeobox A5. (270 aa)
SRCTyrosine-protein kinase. (538 aa)
ENSCHIP00000003193BHLH domain-containing protein. (122 aa)
FOXB1Forkhead box B1. (325 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
PMLPromyelocytic leukemia. (868 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
ELF3E74 like ETS transcription factor 3. (372 aa)
PRP6Prolactin-related protein-6. (239 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (550 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
TBX3T-box transcription factor 3. (749 aa)
SOSTDC1Sclerostin domain containing 1. (206 aa)
LOC102170569Uncharacterized protein. (211 aa)
ATP2C2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (946 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (498 aa)
ENSCHIP00000016419Uncharacterized protein. (230 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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