STRINGSTRING
ARHGEF16 ARHGEF16 PITPNM1 PITPNM1 SOCS5 SOCS5 TRAT1 TRAT1 TOB1 TOB1 CPNE3 CPNE3 PIK3R2 PIK3R2 CRKL CRKL ENSCHIP00000003109 ENSCHIP00000003109 HYAL2 HYAL2 GFRAL GFRAL CBL CBL PITPNM2 PITPNM2 RNF41 RNF41 CRK CRK NCK2 NCK2 SHC3 SHC3 FRS2 FRS2 FNTA FNTA MAP3K7 MAP3K7 ELMO2 ELMO2 NCK1 NCK1 SHC1 SHC1 FLT3LG FLT3LG PTPN2 PTPN2 SHC4 SHC4 PTPN14 PTPN14 MYOC MYOC ZPR1 ZPR1 FRS3 FRS3 PITPNM3 PITPNM3 MST1 MST1 SH2B2 SH2B2 RACK1 RACK1 GAS6 GAS6 ANGPT1 ANGPT1 PCNA PCNA GRB2 GRB2 GAB2 GAB2 ANGPT4 ANGPT4 PTPN1 PTPN1 PSPN PSPN SH2B3 SH2B3 ANGPT2 ANGPT2 PTPN11 PTPN11 ARTN ARTN DOCK4 DOCK4 ALKAL2 ALKAL2 SHC2 SHC2 ENSCHIP00000023661 ENSCHIP00000023661 PIK3R1 PIK3R1 DOK2 DOK2 LOC108634739 LOC108634739 CADM4 CADM4 GDNF GDNF SH2B1 SH2B1 CBLB CBLB LRP4 LRP4 PLCG1 PLCG1 TRADD TRADD CBLC CBLC ENSCHIP00000030107 ENSCHIP00000030107 TP53 TP53 DAZAP2 DAZAP2 GRB14 GRB14 STAP1 STAP1 ALKAL1 ALKAL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARHGEF16Rho guanine nucleotide exchange factor 16. (711 aa)
PITPNM1Phosphatidylinositol transfer protein membrane associated 1. (1246 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
TRAT1T cell receptor associated transmembrane adaptor 1. (198 aa)
TOB1Transducer of ERBB2, 1. (342 aa)
CPNE3Copine 3. (533 aa)
PIK3R2Uncharacterized protein. (724 aa)
CRKLCRK like proto-oncogene, adaptor protein. (302 aa)
ENSCHIP00000003109WD_REPEATS_REGION domain-containing protein. (59 aa)
HYAL2Hyaluronidase. (476 aa)
GFRALGDNF family receptor alpha like. (381 aa)
CBLCbl proto-oncogene. (932 aa)
PITPNM2Phosphatidylinositol transfer protein membrane associated 2. (1318 aa)
RNF41Ring finger protein 41. (317 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
NCK2Cytoplasmic protein. (376 aa)
SHC3SHC adaptor protein 3. (592 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
FNTAUncharacterized protein. (378 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
ELMO2Engulfment and cell motility 2. (725 aa)
NCK1Cytoplasmic protein. (377 aa)
SHC1SHC adaptor protein 1. (583 aa)
FLT3LGFms related tyrosine kinase 3 ligand. (290 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (417 aa)
SHC4SHC adaptor protein 4. (630 aa)
PTPN14Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1189 aa)
MYOCMyocilin. (490 aa)
ZPR1ZPR1 zinc finger. (459 aa)
FRS3Fibroblast growth factor receptor substrate 3. (495 aa)
PITPNM3PITPNM family member 3. (974 aa)
MST1Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (722 aa)
SH2B2SH2B adaptor protein 2. (624 aa)
RACK1Receptor for activated C kinase 1. (317 aa)
GAS6Growth arrest specific 6. (671 aa)
ANGPT1Angiopoietin 1. (488 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
GAB2GRB2 associated binding protein 2. (680 aa)
ANGPT4Angiopoietin 4. (498 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (424 aa)
PSPNPersephin. (126 aa)
SH2B3SH2B adaptor protein 3. (550 aa)
ANGPT2Angiopoietin 2. (498 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
ARTNArtemin. (221 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (1971 aa)
ALKAL2ALK and LTK ligand 2. (151 aa)
SHC2Uncharacterized protein. (565 aa)
ENSCHIP00000023661Uncharacterized protein. (344 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
DOK2Docking protein 2. (413 aa)
LOC108634739TGF_BETA_2 domain-containing protein. (197 aa)
CADM4Cell adhesion molecule 4. (388 aa)
GDNFGlial cell derived neurotrophic factor. (211 aa)
SH2B1SH2B adaptor protein 1. (775 aa)
CBLBCbl proto-oncogene B. (983 aa)
LRP4LDL receptor related protein 4. (1901 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1296 aa)
TRADDTNFRSF1A associated via death domain. (312 aa)
CBLCCbl proto-oncogene C. (489 aa)
ENSCHIP00000030107Uncharacterized protein. (363 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa)
DAZAP2DAZ associated protein 2. (168 aa)
GRB14Growth factor receptor bound protein 14. (540 aa)
STAP1Signal transducing adaptor family member 1. (300 aa)
ALKAL1Uncharacterized protein. (93 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.