34 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102177756	HTH_48 domain-containing protein. (337 aa)
	LOC106502849	Uncharacterized protein. (242 aa)
	BLM	BLM RecQ like helicase. (1429 aa)
	ATRX	ATRX chromatin remodeler. (2105 aa)
	GEN1	GEN1 Holliday junction 5' flap endonuclease. (931 aa)
	RTEL1	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1212 aa)
	RFWD3	Ring finger and WD repeat domain 3. (791 aa)
	WRN	WRN RecQ like helicase. (1405 aa)
	TRAIP	TRAF interacting protein. (471 aa)
	FANCM	FA complementation group M. (2043 aa)
	THOC1	THO complex 1. (657 aa)
	NUCKS1	Uncharacterized protein. (248 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	TONSL	Tonsoku like, DNA repair protein. (1371 aa)
	EME1	Essential meiotic structure-specific endonuclease 1. (580 aa)
	PRIMPOL	Primase and DNA directed polymerase. (554 aa)
	FBH1	F-box DNA helicase 1. (1048 aa)
	CENPS	Centromere protein S. (131 aa)
	BOD1L1	Uncharacterized protein. (2004 aa)
	DNA2	DNA replication helicase/nuclease 2. (1062 aa)
	MMS22L	MMS22 like, DNA repair protein. (1244 aa)
	KHDC3L	MOEP19 domain-containing protein. (325 aa)
	BRCA2	BRCA2 DNA repair associated. (3405 aa)
	MRE11	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (724 aa)
	ENSCHIP00000026753	Uncharacterized protein. (107 aa)
	MUS81	MUS81 structure-specific endonuclease subunit. (552 aa)
	OOEP	Oocyte expressed protein. (140 aa)
	SAMHD1	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (606 aa)
	ETAA1	ETAA1 activator of ATR kinase. (903 aa)
	RAD51	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
	ENSCHIP00000031547	HTH_48 domain-containing protein. (342 aa)
	ZRANB3	Zinc finger RANBP2-type containing 3. (1070 aa)
	SMARCAL1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (930 aa)
	CDK9	Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATRX	BRCA2	ENSCHIP00000011584	ENSCHIP00000024039	ATRX chromatin remodeler.	BRCA2 DNA repair associated.	0.579
ATRX	FANCM	ENSCHIP00000011584	ENSCHIP00000013958	ATRX chromatin remodeler.	FA complementation group M.	0.662
ATRX	MRE11	ENSCHIP00000011584	ENSCHIP00000024516	ATRX chromatin remodeler.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.513
ATRX	MUS81	ENSCHIP00000011584	ENSCHIP00000028466	ATRX chromatin remodeler.	MUS81 structure-specific endonuclease subunit.	0.540
ATRX	PCNA	ENSCHIP00000011584	ENSCHIP00000015091	ATRX chromatin remodeler.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.480
ATRX	RAD51	ENSCHIP00000011584	ENSCHIP00000033023	ATRX chromatin remodeler.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.857
ATRX	RTEL1	ENSCHIP00000011584	ENSCHIP00000012311	ATRX chromatin remodeler.	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	0.433
ATRX	WRN	ENSCHIP00000011584	ENSCHIP00000013642	ATRX chromatin remodeler.	WRN RecQ like helicase.	0.749
BLM	BRCA2	ENSCHIP00000006552	ENSCHIP00000024039	BLM RecQ like helicase.	BRCA2 DNA repair associated.	0.830
BLM	CENPS	ENSCHIP00000006552	ENSCHIP00000016220	BLM RecQ like helicase.	Centromere protein S.	0.619
BLM	DNA2	ENSCHIP00000006552	ENSCHIP00000020258	BLM RecQ like helicase.	DNA replication helicase/nuclease 2.	0.934
BLM	EME1	ENSCHIP00000006552	ENSCHIP00000015587	BLM RecQ like helicase.	Essential meiotic structure-specific endonuclease 1.	0.692
BLM	FANCM	ENSCHIP00000006552	ENSCHIP00000013958	BLM RecQ like helicase.	FA complementation group M.	0.999
BLM	FBH1	ENSCHIP00000006552	ENSCHIP00000015825	BLM RecQ like helicase.	F-box DNA helicase 1.	0.809
BLM	GEN1	ENSCHIP00000006552	ENSCHIP00000011906	BLM RecQ like helicase.	GEN1 Holliday junction 5' flap endonuclease.	0.723
BLM	MRE11	ENSCHIP00000006552	ENSCHIP00000024516	BLM RecQ like helicase.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.924
BLM	MUS81	ENSCHIP00000006552	ENSCHIP00000028466	BLM RecQ like helicase.	MUS81 structure-specific endonuclease subunit.	0.943
BLM	PCNA	ENSCHIP00000006552	ENSCHIP00000015091	BLM RecQ like helicase.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.760
BLM	RAD51	ENSCHIP00000006552	ENSCHIP00000033023	BLM RecQ like helicase.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.967
BLM	RTEL1	ENSCHIP00000006552	ENSCHIP00000012311	BLM RecQ like helicase.	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	0.797