(43 nodes) Regulation of chondrocyte differentiation network (Capra hircus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	CHADL	Chondroadherin like. (738 aa)
	SOX5	SRY-box transcription factor 5. (787 aa)
	GREM1	Gremlin. (184 aa)
	NKX3-2	NK3 homeobox 2. (330 aa)
	PKDCC	Protein kinase domain containing, cytoplasmic. (493 aa)
	FGF18	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	PTHLH	Parathyroid hormone-like protein. (177 aa)
	RARB	Retinoic acid receptor beta. (448 aa)
	CCN4	Cellular communication network factor 4. (368 aa)
	LNPK	Lunapark, ER junction formation factor. (429 aa)
	ZBTB16	Uncharacterized protein. (673 aa)
	ADAMTS7	ADAM metallopeptidase with thrombospondin type 1 motif 7. (1677 aa)
	GDF5	Growth differentiation factor 5. (499 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	SCIN	Scinderin. (715 aa)
	GLI3	GLI family zinc finger 3. (1614 aa)
	LOXL2	Lysyl oxidase like 2. (791 aa)
	RUNX2	RUNX family transcription factor 2. (585 aa)
	SHOX2	Short stature homeobox 2. (319 aa)
	ZNF219	Zinc finger protein 219. (734 aa)
	IHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
	RFLNA	Refilin A. (200 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
	SMAD7	Mothers against decapentaplegic homolog. (427 aa)
	GDF6	Growth differentiation factor 6. (463 aa)
	ADAMTS12	ADAM metallopeptidase with thrombospondin type 1 motif 12. (1605 aa)
	AXIN2	Axin 2. (844 aa)
	HOXA11	Homeobox A11. (317 aa)
	MUSTN1	Uncharacterized protein. (86 aa)
	EFEMP1	EGF containing fibulin extracellular matrix protein 1. (498 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	SOX9	SRY-box transcription factor 9. (525 aa)
	SOX6	SRY-box transcription factor 6. (858 aa)
	TGFBR1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
	MAF	MAF bZIP transcription factor; Belongs to the bZIP family. (404 aa)
	RARG	Retinoic acid receptor gamma. (458 aa)
	LTBP3	Latent transforming growth factor beta binding protein 3. (1294 aa)
	SNAI2	Snail family transcriptional repressor 2. (268 aa)
	GLG1	Golgi glycoprotein 1. (1234 aa)
	SIX2	SIX homeobox 2. (296 aa)
	CCN2	Cellular communication network factor 2. (349 aa)
	RFLNB	Refilin B. (216 aa)
	CTNNB1	Catenin beta 1. (781 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN2	BMP4	ENSCHIP00000022676	ENSCHIP00000023678	Axin 2.	Bone morphogenetic protein 4.	0.715
AXIN2	CCN4	ENSCHIP00000022676	ENSCHIP00000009471	Axin 2.	Cellular communication network factor 4.	0.499
AXIN2	CTNNB1	ENSCHIP00000022676	ENSCHIP00000031016	Axin 2.	Catenin beta 1.	0.998
AXIN2	GLI3	ENSCHIP00000022676	ENSCHIP00000014153	Axin 2.	GLI family zinc finger 3.	0.489
AXIN2	IHH	ENSCHIP00000022676	ENSCHIP00000016239	Axin 2.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.413
AXIN2	RUNX2	ENSCHIP00000022676	ENSCHIP00000015454	Axin 2.	RUNX family transcription factor 2.	0.701
AXIN2	SMAD7	ENSCHIP00000022676	ENSCHIP00000021001	Axin 2.	Mothers against decapentaplegic homolog.	0.486
AXIN2	SOX9	ENSCHIP00000022676	ENSCHIP00000024523	Axin 2.	SRY-box transcription factor 9.	0.731
BMP4	AXIN2	ENSCHIP00000023678	ENSCHIP00000022676	Bone morphogenetic protein 4.	Axin 2.	0.715
BMP4	CCN2	ENSCHIP00000023678	ENSCHIP00000030116	Bone morphogenetic protein 4.	Cellular communication network factor 2.	0.707
BMP4	CTNNB1	ENSCHIP00000023678	ENSCHIP00000031016	Bone morphogenetic protein 4.	Catenin beta 1.	0.800
BMP4	FGF18	ENSCHIP00000023678	ENSCHIP00000008198	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.700
BMP4	GDF5	ENSCHIP00000023678	ENSCHIP00000009728	Bone morphogenetic protein 4.	Growth differentiation factor 5.	0.530
BMP4	GDF6	ENSCHIP00000023678	ENSCHIP00000021163	Bone morphogenetic protein 4.	Growth differentiation factor 6.	0.472
BMP4	GLI3	ENSCHIP00000023678	ENSCHIP00000014153	Bone morphogenetic protein 4.	GLI family zinc finger 3.	0.499
BMP4	GREM1	ENSCHIP00000023678	ENSCHIP00000006985	Bone morphogenetic protein 4.	Gremlin.	0.946
BMP4	IHH	ENSCHIP00000023678	ENSCHIP00000016239	Bone morphogenetic protein 4.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.790
BMP4	RUNX2	ENSCHIP00000023678	ENSCHIP00000015454	Bone morphogenetic protein 4.	RUNX family transcription factor 2.	0.900
BMP4	SHOX2	ENSCHIP00000023678	ENSCHIP00000015506	Bone morphogenetic protein 4.	Short stature homeobox 2.	0.525
BMP4	SMAD3	ENSCHIP00000023678	ENSCHIP00000011729	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.808