Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADAM17 | APP | ENSCHIP00000011530 | ENSCHIP00000032622 | ADAM metallopeptidase domain 17. | Amyloid beta precursor protein. | 0.644 |
| ADAM17 | IFNG | ENSCHIP00000011530 | ENSCHIP00000016152 | ADAM metallopeptidase domain 17. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. | 0.434 |
| ADAM17 | IL1B | ENSCHIP00000011530 | ENSCHIP00000029274 | ADAM metallopeptidase domain 17. | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | 0.460 |
| ADAM17 | IL6R | ENSCHIP00000011530 | ENSCHIP00000009581 | ADAM metallopeptidase domain 17. | Interleukin 6 receptor. | 0.546 |
| ADAM17 | TNF | ENSCHIP00000011530 | ENSCHIP00000004561 | ADAM metallopeptidase domain 17. | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | 0.911 |
| ADIPOQ | IFNG | ENSCHIP00000032803 | ENSCHIP00000016152 | C1q domain-containing protein. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. | 0.501 |
| ADIPOQ | IL1B | ENSCHIP00000032803 | ENSCHIP00000029274 | C1q domain-containing protein. | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | 0.742 |
| ADIPOQ | LPL | ENSCHIP00000032803 | ENSCHIP00000031249 | C1q domain-containing protein. | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. | 0.762 |
| ADIPOQ | TLR4 | ENSCHIP00000032803 | ENSCHIP00000019512 | C1q domain-containing protein. | TIR domain-containing protein; Belongs to the Toll-like receptor family. | 0.530 |
| ADIPOQ | TNF | ENSCHIP00000032803 | ENSCHIP00000004561 | C1q domain-containing protein. | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | 0.762 |
| AGER | APP | ENSCHIP00000011860 | ENSCHIP00000032622 | Advanced glycosylation end-product specific receptor. | Amyloid beta precursor protein. | 0.674 |
| AGER | IL1B | ENSCHIP00000011860 | ENSCHIP00000029274 | Advanced glycosylation end-product specific receptor. | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | 0.443 |
| AGER | SYK | ENSCHIP00000011860 | ENSCHIP00000009361 | Advanced glycosylation end-product specific receptor. | Spleen associated tyrosine kinase. | 0.465 |
| AGER | TLR4 | ENSCHIP00000011860 | ENSCHIP00000019512 | Advanced glycosylation end-product specific receptor. | TIR domain-containing protein; Belongs to the Toll-like receptor family. | 0.502 |
| AIF1 | CSF1R | ENSCHIP00000028430 | ENSCHIP00000033005 | Allograft inflammatory factor 1. | Colony stimulating factor 1 receptor. | 0.498 |
| AIF1 | IL1B | ENSCHIP00000028430 | ENSCHIP00000029274 | Allograft inflammatory factor 1. | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | 0.583 |
| AIF1 | PYCARD | ENSCHIP00000028430 | ENSCHIP00000027015 | Allograft inflammatory factor 1. | PYD and CARD domain containing. | 0.552 |
| AIF1 | TLR4 | ENSCHIP00000028430 | ENSCHIP00000019512 | Allograft inflammatory factor 1. | TIR domain-containing protein; Belongs to the Toll-like receptor family. | 0.407 |
| AIF1 | TNF | ENSCHIP00000028430 | ENSCHIP00000004561 | Allograft inflammatory factor 1. | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | 0.496 |
| AIRE | IL17F | ENSCHIP00000017845 | ENSCHIP00000004124 | Autoimmune regulator. | Uncharacterized protein. | 0.453 |
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