STRINGSTRING
CDC45 CDC45 PCNA PCNA RTF2 RTF2 POLA1 POLA1 ATAD5 ATAD5 MCM6 MCM6 MCM4 MCM4 DNA2 DNA2 GMNN GMNN MCM2 MCM2 MCM3 MCM3 DONSON DONSON GINS3 GINS3 BRCA2 BRCA2 RTEL1 RTEL1 ZNF830 ZNF830 CDT1 CDT1 UPF1 UPF1 GINS1 GINS1 RAD51 RAD51 LIG1 LIG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDC45Cell division cycle 45. (524 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
RTF2Replication termination factor 2. (341 aa)
POLA1DNA polymerase. (1468 aa)
ATAD5ATPase family AAA domain containing 5. (1894 aa)
MCM6DNA helicase; Belongs to the MCM family. (821 aa)
MCM4DNA helicase; Belongs to the MCM family. (851 aa)
DNA2DNA replication helicase/nuclease 2. (1062 aa)
GMNNGeminin DNA replication inhibitor. (186 aa)
MCM2DNA helicase; Belongs to the MCM family. (1061 aa)
MCM3DNA helicase; Belongs to the MCM family. (808 aa)
DONSONDownstream neighbor of SON. (561 aa)
GINS3GINS complex subunit 3. (216 aa)
BRCA2BRCA2 DNA repair associated. (3405 aa)
RTEL1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1212 aa)
ZNF830Zinc finger protein 830. (361 aa)
CDT1Chromatin licensing and DNA replication factor 1. (637 aa)
UPF1UPF1 RNA helicase and ATPase. (1126 aa)
GINS1GINS complex subunit 1. (196 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
LIG1DNA ligase. (915 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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