12 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	LOC102172393	5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (201 aa)
	MTHFR	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (655 aa)
	DHFR	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa)
	SHMT1	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
	MTHFD2L	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. (347 aa)
	MTHFD1L	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (975 aa)
	LOC102169668	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (188 aa)
	SHMT2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (502 aa)
	MTHFD1	Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (935 aa)
	FTCD	Formimidoyltransferase cyclodeaminase. (540 aa)
	MTHFD2	Uncharacterized protein. (352 aa)
	ENSCHIP00000021405	DHFR domain-containing protein. (156 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DHFR	FTCD	ENSCHIP00000015609	ENSCHIP00000006703	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Formimidoyltransferase cyclodeaminase.	0.926
DHFR	MTHFD1	ENSCHIP00000015609	ENSCHIP00000001307	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1.	0.971
DHFR	MTHFD1L	ENSCHIP00000015609	ENSCHIP00000032334	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.	0.956
DHFR	MTHFD2	ENSCHIP00000015609	ENSCHIP00000024076	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Uncharacterized protein.	0.753
DHFR	MTHFR	ENSCHIP00000015609	ENSCHIP00000031461	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.758
DHFR	SHMT1	ENSCHIP00000015609	ENSCHIP00000011211	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.987
DHFR	SHMT2	ENSCHIP00000015609	ENSCHIP00000001693	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.985
ENSCHIP00000021405	MTHFD1	ENSCHIP00000021405	ENSCHIP00000001307	DHFR domain-containing protein.	Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1.	0.420
ENSCHIP00000021405	MTHFD1L	ENSCHIP00000021405	ENSCHIP00000032334	DHFR domain-containing protein.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.	0.420
ENSCHIP00000021405	SHMT1	ENSCHIP00000021405	ENSCHIP00000011211	DHFR domain-containing protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.614
ENSCHIP00000021405	SHMT2	ENSCHIP00000021405	ENSCHIP00000001693	DHFR domain-containing protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.614
FTCD	DHFR	ENSCHIP00000006703	ENSCHIP00000015609	Formimidoyltransferase cyclodeaminase.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.926
FTCD	LOC102172393	ENSCHIP00000006703	ENSCHIP00000015675	Formimidoyltransferase cyclodeaminase.	5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.	0.977
FTCD	MTHFD1	ENSCHIP00000006703	ENSCHIP00000001307	Formimidoyltransferase cyclodeaminase.	Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1.	0.971
FTCD	MTHFD1L	ENSCHIP00000006703	ENSCHIP00000032334	Formimidoyltransferase cyclodeaminase.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.	0.971
FTCD	MTHFD2	ENSCHIP00000006703	ENSCHIP00000024076	Formimidoyltransferase cyclodeaminase.	Uncharacterized protein.	0.971
FTCD	MTHFD2L	ENSCHIP00000006703	ENSCHIP00000009047	Formimidoyltransferase cyclodeaminase.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like.	0.971
FTCD	MTHFR	ENSCHIP00000006703	ENSCHIP00000031461	Formimidoyltransferase cyclodeaminase.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.610
FTCD	SHMT1	ENSCHIP00000006703	ENSCHIP00000011211	Formimidoyltransferase cyclodeaminase.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.938
FTCD	SHMT2	ENSCHIP00000006703	ENSCHIP00000001693	Formimidoyltransferase cyclodeaminase.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.930