35 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DCLRE1A	DNA cross-link repair 1A. (1051 aa)
	DCLRE1B	DNA cross-link repair 1B. (542 aa)
	ERCC4	ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
	FANCC	Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. (568 aa)
	FANCG	FA complementation group G. (616 aa)
	FAAP24	FA core complex associated protein 24. (215 aa)
	FAN1	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1022 aa)
	FAAP20	Uncharacterized protein. (192 aa)
	RAD51D	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily. (338 aa)
	FANCL	RING-type domain-containing protein. (379 aa)
	FAAP100	FA core complex associated protein 100. (879 aa)
	MCM9	Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1137 aa)
	VCP	Valosin containing protein; Belongs to the AAA ATPase family. (816 aa)
	SLX4	SLX4 structure-specific endonuclease subunit. (1752 aa)
	CENPS	Centromere protein S. (131 aa)
	NUCKS1	Uncharacterized protein. (248 aa)
	FANCB	Uncharacterized protein. (447 aa)
	DCLRE1C	DNA cross-link repair 1C. (710 aa)
	FANCM	FA complementation group M. (2043 aa)
	MCM8	MCM domain-containing protein; Belongs to the MCM family. (832 aa)
	RFWD3	Ring finger and WD repeat domain 3. (791 aa)
	RAD51AP1	RAD51 associated protein 1. (326 aa)
	XPA	XPA, DNA damage recognition and repair factor. (273 aa)
	NEIL3	Nei like DNA glycosylase 3. (606 aa)
	ENSCHIP00000003676	RECA_2 domain-containing protein. (278 aa)
	EXO5	Exonuclease 5. (370 aa)
	FANCF	FA complementation group F. (359 aa)
	LOC106502849	Uncharacterized protein. (242 aa)
	ENSCHIP00000002303	Uncharacterized protein. (84 aa)
	RAD51	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
	FANCA	FA complementation group A. (1416 aa)
	FANCD2	FA complementation group D2. (1423 aa)
	ERCC1	ERCC excision repair 1, endonuclease non-catalytic subunit. (294 aa)
	ENSCHIP00000029183	Uncharacterized protein. (373 aa)
	FANCE	FA complementation group E. (444 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CENPS	DCLRE1B	ENSCHIP00000016220	ENSCHIP00000028064	Centromere protein S.	DNA cross-link repair 1B.	0.533
CENPS	ENSCHIP00000002303	ENSCHIP00000016220	ENSCHIP00000002303	Centromere protein S.	Uncharacterized protein.	0.665
CENPS	ENSCHIP00000029183	ENSCHIP00000016220	ENSCHIP00000029183	Centromere protein S.	Uncharacterized protein.	0.823
CENPS	ERCC1	ENSCHIP00000016220	ENSCHIP00000031141	Centromere protein S.	ERCC excision repair 1, endonuclease non-catalytic subunit.	0.509
CENPS	ERCC4	ENSCHIP00000016220	ENSCHIP00000026065	Centromere protein S.	ERCC excision repair 4, endonuclease catalytic subunit.	0.624
CENPS	FAAP100	ENSCHIP00000016220	ENSCHIP00000020356	Centromere protein S.	FA core complex associated protein 100.	0.917
CENPS	FAAP20	ENSCHIP00000016220	ENSCHIP00000023150	Centromere protein S.	Uncharacterized protein.	0.554
CENPS	FAAP24	ENSCHIP00000016220	ENSCHIP00000023626	Centromere protein S.	FA core complex associated protein 24.	0.936
CENPS	FANCA	ENSCHIP00000016220	ENSCHIP00000001913	Centromere protein S.	FA complementation group A.	0.929
CENPS	FANCB	ENSCHIP00000016220	ENSCHIP00000014817	Centromere protein S.	Uncharacterized protein.	0.864
CENPS	FANCC	ENSCHIP00000016220	ENSCHIP00000024710	Centromere protein S.	Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.	0.878
CENPS	FANCD2	ENSCHIP00000016220	ENSCHIP00000032582	Centromere protein S.	FA complementation group D2.	0.613
CENPS	FANCE	ENSCHIP00000016220	ENSCHIP00000028621	Centromere protein S.	FA complementation group E.	0.777
CENPS	FANCF	ENSCHIP00000016220	ENSCHIP00000003311	Centromere protein S.	FA complementation group F.	0.899
CENPS	FANCG	ENSCHIP00000016220	ENSCHIP00000024561	Centromere protein S.	FA complementation group G.	0.883
CENPS	FANCL	ENSCHIP00000016220	ENSCHIP00000020403	Centromere protein S.	RING-type domain-containing protein.	0.823
CENPS	FANCM	ENSCHIP00000016220	ENSCHIP00000013958	Centromere protein S.	FA complementation group M.	0.994
DCLRE1A	DCLRE1B	ENSCHIP00000016205	ENSCHIP00000028064	DNA cross-link repair 1A.	DNA cross-link repair 1B.	0.444
DCLRE1A	ENSCHIP00000029183	ENSCHIP00000016205	ENSCHIP00000029183	DNA cross-link repair 1A.	Uncharacterized protein.	0.507
DCLRE1A	ERCC1	ENSCHIP00000016205	ENSCHIP00000031141	DNA cross-link repair 1A.	ERCC excision repair 1, endonuclease non-catalytic subunit.	0.659