STRINGSTRING
BMP7 BMP7 FAM20A FAM20A SP7 SP7 ENSCHIP00000033272 ENSCHIP00000033272 AQP1 AQP1 PPARA PPARA MMP20 MMP20 NECTIN1 NECTIN1 AMBN AMBN INHBA INHBA LAMB1 LAMB1 CTNNB1 CTNNB1 LEF1 LEF1 KLK4 KLK4 FAM20C FAM20C DLX2 DLX2 LRP4 LRP4 EDAR EDAR ID3 ID3 TP63 TP63 SHH SHH WNT6 WNT6 SMO SMO WNT10A WNT10A TCIRG1 TCIRG1 SSUH2 SSUH2 SNX10 SNX10 COL1A1 COL1A1 AQP3 AQP3 BMP4 BMP4 LHX8 LHX8 HDAC1 HDAC1 AXIN2 AXIN2 BCL2L11 BCL2L11 OSR1 OSR1 SMPD3 SMPD3 BCL11B BCL11B OSR2 OSR2 NGFR NGFR ANKH ANKH CFTR CFTR ENAM ENAM KLK5 KLK5 TSPEAR TSPEAR NKX2-3 NKX2-3 STIM1 STIM1 ENSCHIP00000017739 ENSCHIP00000017739 PAX9 PAX9 FGF8 FGF8 FST FST DSPP DSPP AMTN AMTN RUNX2 RUNX2 TRAF6 TRAF6 JAG2 JAG2 ODAM ODAM GLI3 GLI3 SLC24A4 SLC24A4 TNFSF11 TNFSF11 RELT RELT DLX1 DLX1 ANKRD11 ANKRD11 NF2 NF2 MSX1 MSX1 ITGB6 ITGB6 RHOA RHOA CNNM4 CNNM4 CCDC154 CCDC154 ENSCHIP00000011371 ENSCHIP00000011371 BMP2 BMP2 FGF10 FGF10 HAND2 HAND2 SOSTDC1 SOSTDC1 TGFB1 TGFB1 LAMA5 LAMA5 LOC106501902 LOC106501902 EDA EDA DLX3 DLX3 WDR72 WDR72 PITX2 PITX2 FGF4 FGF4 BCOR BCOR AQP5 AQP5 LOC108634548 LOC108634548 SRC SRC ROGDI ROGDI PDGFRA PDGFRA HAND1 HAND1 BMPR1A BMPR1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMP7Bone morphogenetic protein 7. (431 aa)
FAM20AFAM20A golgi associated secretory pathway pseudokinase. (535 aa)
SP7Sp7 transcription factor. (431 aa)
ENSCHIP00000033272FERM domain-containing protein. (580 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
PPARAPeroxisome proliferator activated receptor alpha. (470 aa)
MMP20Matrix metallopeptidase 20. (483 aa)
NECTIN1Nectin cell adhesion molecule 1. (515 aa)
AMBNAmeloblastin. (414 aa)
INHBAInhibin beta A subunit. (425 aa)
LAMB1Laminin subunit beta 1. (1842 aa)
CTNNB1Catenin beta 1. (781 aa)
LEF1HMG box domain-containing protein. (430 aa)
KLK4Kallikrein related peptidase 4; Belongs to the peptidase S1 family. (255 aa)
FAM20CFAM20C golgi associated secretory pathway kinase. (614 aa)
DLX2Distal-less homeobox 2. (328 aa)
LRP4LDL receptor related protein 4. (1901 aa)
EDAREctodysplasin A receptor. (441 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (151 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (681 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (780 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (416 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (829 aa)
SSUH2Ssu-2 homolog. (328 aa)
SNX10Sorting nexin 10. (200 aa)
COL1A1Collagen type I alpha 1 chain. (1463 aa)
AQP3Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family. (295 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
LHX8LIM homeobox 8. (377 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (464 aa)
AXIN2Axin 2. (844 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (195 aa)
OSR1Odd-skipped related transcription factor 1. (267 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (656 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (905 aa)
OSR2Odd-skipped related transciption factor 2. (276 aa)
NGFRNerve growth factor receptor. (427 aa)
ANKHANKH inorganic pyrophosphate transport regulator. (492 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1524 aa)
ENAMEnamelin. (1156 aa)
KLK5Kallikrein related peptidase 5; Belongs to the peptidase S1 family. (293 aa)
TSPEARThrombospondin type laminin G domain and EAR repeats. (670 aa)
NKX2-3NK2 homeobox 3. (367 aa)
STIM1Stromal interaction molecule 1. (714 aa)
ENSCHIP00000017739Uncharacterized protein. (202 aa)
PAX9Paired box 9. (342 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
FSTUncharacterized protein. (344 aa)
DSPPDentin sialophosphoprotein. (1171 aa)
AMTNAmelotin. (211 aa)
RUNX2RUNX family transcription factor 2. (585 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (573 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1069 aa)
ODAMOdontogenic, ameloblast associated. (274 aa)
GLI3GLI family zinc finger 3. (1614 aa)
SLC24A4Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (603 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (316 aa)
RELTRELT TNF receptor. (425 aa)
DLX1Distal-less homeobox 1. (255 aa)
ANKRD11ANK_REP_REGION domain-containing protein. (2590 aa)
NF2FERM domain-containing protein. (612 aa)
MSX1Msh homeobox 1. (303 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (844 aa)
RHOARas-like protein family member A. (193 aa)
CNNM4Cyclin and CBS domain divalent metal cation transport mediator 4. (775 aa)
CCDC154Coiled-coil domain containing 154. (672 aa)
ENSCHIP00000011371Uncharacterized protein. (193 aa)
BMP2TGF_BETA_2 domain-containing protein. (381 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
SOSTDC1Sclerostin domain containing 1. (206 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
LAMA5Laminin subunit alpha 5. (2263 aa)
LOC106501902ANK_REP_REGION domain-containing protein. (2545 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (257 aa)
DLX3Distal-less homeobox 3. (287 aa)
WDR72WD repeat domain 72. (1100 aa)
PITX2Homeobox protein. (325 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
BCORBCL6 corepressor. (1738 aa)
AQP5Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (265 aa)
LOC108634548Uncharacterized protein. (190 aa)
SRCTyrosine-protein kinase. (538 aa)
ROGDIRogdi atypical leucine zipper. (287 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1108 aa)
HAND1Heart and neural crest derivatives expressed 1. (219 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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