Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABL1 | ATM | ENSCHIP00000024651 | ENSCHIP00000016363 | Tyrosine-protein kinase. | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | 0.919 |
| ABL1 | BRCA1 | ENSCHIP00000024651 | ENSCHIP00000033014 | Tyrosine-protein kinase. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.620 |
| ABL1 | BRCA2 | ENSCHIP00000024651 | ENSCHIP00000024039 | Tyrosine-protein kinase. | BRCA2 DNA repair associated. | 0.423 |
| ABL1 | CCND1 | ENSCHIP00000024651 | ENSCHIP00000006815 | Tyrosine-protein kinase. | Cyclin D1; Belongs to the cyclin family. | 0.464 |
| ABL1 | CDKN1A | ENSCHIP00000024651 | ENSCHIP00000002564 | Tyrosine-protein kinase. | Cyclin dependent kinase inhibitor 1A. | 0.511 |
| ABL1 | GRB2 | ENSCHIP00000024651 | ENSCHIP00000015407 | Tyrosine-protein kinase. | Growth factor receptor bound protein 2. | 0.964 |
| ABL1 | MRE11 | ENSCHIP00000024651 | ENSCHIP00000024516 | Tyrosine-protein kinase. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.458 |
| ABL1 | NBN | ENSCHIP00000024651 | ENSCHIP00000007769 | Tyrosine-protein kinase. | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. | 0.523 |
| ABL1 | PTPN11 | ENSCHIP00000024651 | ENSCHIP00000020822 | Tyrosine-protein kinase. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.414 |
| ABL1 | TP53 | ENSCHIP00000024651 | ENSCHIP00000030141 | Tyrosine-protein kinase. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.635 |
| ABRAXAS1 | ATM | ENSCHIP00000016332 | ENSCHIP00000016363 | Abraxas 1, BRCA1 A complex subunit. | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | 0.657 |
| ABRAXAS1 | BABAM1 | ENSCHIP00000016332 | ENSCHIP00000030063 | Abraxas 1, BRCA1 A complex subunit. | BRISC and BRCA1 A complex member 1. | 0.999 |
| ABRAXAS1 | BABAM2 | ENSCHIP00000016332 | ENSCHIP00000001607 | Abraxas 1, BRCA1 A complex subunit. | BRISC and BRCA1 A complex member 2. | 0.999 |
| ABRAXAS1 | BRCA1 | ENSCHIP00000016332 | ENSCHIP00000033014 | Abraxas 1, BRCA1 A complex subunit. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.994 |
| ABRAXAS1 | BRCA2 | ENSCHIP00000016332 | ENSCHIP00000024039 | Abraxas 1, BRCA1 A complex subunit. | BRCA2 DNA repair associated. | 0.552 |
| ABRAXAS1 | BRCC3 | ENSCHIP00000016332 | ENSCHIP00000019173 | Abraxas 1, BRCA1 A complex subunit. | MPN domain-containing protein. | 0.992 |
| ABRAXAS1 | CHEK2 | ENSCHIP00000016332 | ENSCHIP00000027824 | Abraxas 1, BRCA1 A complex subunit. | Checkpoint kinase 2. | 0.763 |
| ABRAXAS1 | ENSCHIP00000001380 | ENSCHIP00000016332 | ENSCHIP00000001380 | Abraxas 1, BRCA1 A complex subunit. | Reverse transcriptase domain-containing protein. | 0.941 |
| ABRAXAS1 | ENSCHIP00000003493 | ENSCHIP00000016332 | ENSCHIP00000003493 | Abraxas 1, BRCA1 A complex subunit. | MPN domain-containing protein. | 0.964 |
| ABRAXAS1 | ENSCHIP00000020042 | ENSCHIP00000016332 | ENSCHIP00000020042 | Abraxas 1, BRCA1 A complex subunit. | MPN domain-containing protein. | 0.964 |
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