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ADK ADK PDXK PDXK BHMT BHMT LOC102176691 LOC102176691 UCK1 UCK1 FCSK FCSK PNP PNP AMPD2 AMPD2 AMPD3 AMPD3 NAPRT NAPRT UPP1 UPP1 MTAP MTAP MROH6 MROH6 UCKL1 UCKL1 PGM2 PGM2 HPRT1 HPRT1 AMPD1 AMPD1 ADSL ADSL ADI1 ADI1 UPP2 UPP2 APRT APRT PRTFDC1 PRTFDC1 MRI1 MRI1 ENSCHIP00000022067 ENSCHIP00000022067 ENSCHIP00000026638 ENSCHIP00000026638 ENOPH1 ENOPH1 UCK2 UCK2 DGUOK DGUOK DCK DCK APIP APIP BHMT2 BHMT2 ADA ADA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ADKAdenosine kinase. (362 aa)
PDXKPyridoxal kinase. (321 aa)
BHMTBetaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism. (407 aa)
LOC102176691Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa)
UCK1Uridine-cytidine kinase; Belongs to the uridine kinase family. (277 aa)
FCSKFucose kinase. (1070 aa)
PNPPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa)
AMPD2AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (817 aa)
AMPD3AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (786 aa)
NAPRTNicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (527 aa)
UPP1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (312 aa)
MTAPS-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (283 aa)
MROH6Maestro heat like repeat family member 6. (693 aa)
UCKL1Uridine-cytidine kinase; Belongs to the uridine kinase family. (552 aa)
PGM2Phosphoglucomutase 2. (629 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
AMPD1AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (731 aa)
ADSLAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (490 aa)
ADI11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (179 aa)
UPP2Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (330 aa)
APRTAdenine phosphoribosyltransferase. (180 aa)
PRTFDC1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (225 aa)
MRI1Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (363 aa)
ENSCHIP00000022067Lyase_1 domain-containing protein. (447 aa)
ENSCHIP00000026638Uncharacterized protein. (190 aa)
ENOPH1Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (261 aa)
UCK2Uridine-cytidine kinase; Belongs to the uridine kinase family. (261 aa)
DGUOKDeoxyguanosine kinase. (277 aa)
DCKDeoxycytidine kinase. (260 aa)
APIPMethylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (242 aa)
BHMT2Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism. (377 aa)
ADAAdenosine deaminase. (400 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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