STRINGSTRING
MEOX2 MEOX2 ENSCHIP00000011995 ENSCHIP00000011995 MEF2C MEF2C MMRN2 MMRN2 FGF2 FGF2 ANGPT2 ANGPT2 ENSCHIP00000020611 ENSCHIP00000020611 ITGB1BP1 ITGB1BP1 NOTCH1 NOTCH1 PDCD10 PDCD10 HDAC5 HDAC5 STARD13 STARD13 LOC102176524 LOC102176524 TNF TNF TGFB1 TGFB1 TBXA2R TBXA2R ENSCHIP00000011371 ENSCHIP00000011371 CSNK2B CSNK2B SPRED1 SPRED1 ENSCHIP00000017024 ENSCHIP00000017024 LY6G5B LY6G5B THBS1 THBS1 ANGPT4 ANGPT4 DLL4 DLL4 VASH1 VASH1 ACVRL1 ACVRL1 JUP JUP GADD45A GADD45A CARD10 CARD10 ENSCHIP00000027417 ENSCHIP00000027417 MECP2 MECP2 APOE APOE RHOA RHOA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MEOX2Mesenchyme homeobox 2. (303 aa)
ENSCHIP00000011995Uncharacterized protein. (126 aa)
MEF2CMADS-box domain-containing protein. (441 aa)
MMRN2Multimerin 2. (937 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
ANGPT2Angiopoietin 2. (498 aa)
ENSCHIP00000020611Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (291 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (199 aa)
NOTCH1Notch receptor 1. (2508 aa)
PDCD10Uncharacterized protein. (212 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1142 aa)
STARD13StAR related lipid transfer domain containing 13. (1121 aa)
LOC102176524Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1242 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
TBXA2RThromboxane A2 receptor. (343 aa)
ENSCHIP00000011371Uncharacterized protein. (193 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (217 aa)
SPRED1Sprouty related EVH1 domain containing 1. (433 aa)
ENSCHIP00000017024PID domain-containing protein. (190 aa)
LY6G5BLymphocyte antigen 6 family member G5B. (196 aa)
THBS1Thrombospondin 1. (1218 aa)
ANGPT4Angiopoietin 4. (498 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (701 aa)
VASH1Vasohibin 1. (363 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
JUPJunction plakoglobin. (745 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (165 aa)
CARD10Caspase recruitment domain family member 10. (1027 aa)
ENSCHIP00000027417Uncharacterized protein. (185 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (481 aa)
APOEApolipoprotein E. (326 aa)
RHOARas-like protein family member A. (193 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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