STRINGSTRING
PIK3R4 PIK3R4 PTK2B PTK2B WDR81 WDR81 SOCS2 SOCS2 SOCS1 SOCS1 ENSCHIP00000000483 ENSCHIP00000000483 RB1 RB1 SOCS5 SOCS5 PDGFRA PDGFRA PIK3R2 PIK3R2 DAB2IP DAB2IP FGFR3 FGFR3 SOCS4 SOCS4 PIK3IP1 PIK3IP1 CD81 CD81 RBL1 RBL1 PIP4K2C PIP4K2C ENSCHIP00000007355 ENSCHIP00000007355 SLA2 SLA2 SOCS3 SOCS3 TGFB1 TGFB1 SOCS7 SOCS7 ENSCHIP00000009861 ENSCHIP00000009861 CDC42 CDC42 TEK TEK WDR91 WDR91 ENSCHIP00000012512 ENSCHIP00000012512 P3R3URF P3R3URF CISH CISH FGR FGR ATG14 ATG14 PIK3R3 PIK3R3 VAV3 VAV3 EEF1A2 EEF1A2 AMBRA1 AMBRA1 RUBCN RUBCN PPP2R5A PPP2R5A LOC108637522 LOC108637522 DGKZ DGKZ FGF2 FGF2 CCL19 CCL19 LOC108635484 LOC108635484 ENSCHIP00000020708 ENSCHIP00000020708 FLT1 FLT1 PIK3R1 PIK3R1 PIK3R5 PIK3R5 VAV2 VAV2 LYN LYN PIP4K2A PIP4K2A PIP4K2B PIP4K2B ENSCHIP00000027249 ENSCHIP00000027249 EPHA8 EPHA8 CD19 CD19 F2 F2 NOD2 NOD2 SOCS6 SOCS6 PDGFRB PDGFRB PIK3R6 PIK3R6 RBL2 RBL2 PDGFB PDGFB CCL21 CCL21
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1310 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
WDR81WD repeat domain 81. (1932 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
SOCS1Suppressor of cytokine signaling 1. (219 aa)
ENSCHIP00000000483Uncharacterized protein. (304 aa)
RB1RB transcriptional corepressor 1. (931 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1108 aa)
PIK3R2Uncharacterized protein. (724 aa)
DAB2IPDAB2 interacting protein. (1198 aa)
FGFR3Receptor protein-tyrosine kinase. (710 aa)
SOCS4Suppressor of cytokine signaling 4. (440 aa)
PIK3IP1Phosphoinositide-3-kinase interacting protein 1. (261 aa)
CD81Tetraspanin. (236 aa)
RBL1RB transcriptional corepressor like 1. (1068 aa)
PIP4K2CPhosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (421 aa)
ENSCHIP00000007355Uncharacterized protein. (288 aa)
SLA2Src like adaptor 2. (276 aa)
SOCS3Suppressor of cytokine signaling 3. (229 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SOCS7Suppressor of cytokine signaling 7. (575 aa)
ENSCHIP00000009861Protein kinase domain-containing protein. (292 aa)
CDC42Uncharacterized protein. (191 aa)
TEKTEK receptor tyrosine kinase. (1125 aa)
WDR91WD repeat domain 91. (740 aa)
ENSCHIP00000012512Uncharacterized protein. (435 aa)
P3R3URFPIK3R3 upstream reading frame. (95 aa)
CISHCytokine inducible SH2 containing protein. (254 aa)
FGRTyrosine-protein kinase. (527 aa)
ATG14Autophagy related 14. (492 aa)
PIK3R3Uncharacterized protein. (461 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
EEF1A2Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (463 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1300 aa)
RUBCNRubicon autophagy regulator. (986 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (492 aa)
LOC108637522Uncharacterized protein. (288 aa)
DGKZDiacylglycerol kinase. (1122 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
CCL19C-C motif chemokine. (102 aa)
LOC108635484Protein kinase domain-containing protein. (677 aa)
ENSCHIP00000020708Protein kinase domain-containing protein. (969 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1337 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (898 aa)
VAV2Vav guanine nucleotide exchange factor 2. (872 aa)
LYNTyrosine-protein kinase. (512 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (404 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa)
ENSCHIP00000027249Protein kinase domain-containing protein. (292 aa)
EPHA8EPH receptor A8. (1005 aa)
CD19CD19 molecule. (561 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
NOD2Uncharacterized protein. (982 aa)
SOCS6Uncharacterized protein. (510 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (762 aa)
RBL2RB transcriptional corepressor like 2. (1140 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
CCL21C-C motif chemokine ligand 21. (131 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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