STRINGSTRING
BBS4 BBS4 SIRT1 SIRT1 CCND1 CCND1 EBI3 EBI3 UGCG UGCG PID1 PID1 INHBB INHBB MKKS MKKS LEPR LEPR BBS2 BBS2 STAT3 STAT3 LEP LEP MT3 MT3 LRP2 LRP2 NR1D1 NR1D1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BBS4Bardet-Biedl syndrome 4. (519 aa)
SIRT1Deacetylase sirtuin-type domain-containing protein. (732 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
EBI3Epstein-Barr virus induced 3. (232 aa)
UGCGUDP-glucose ceramide glucosyltransferase. (394 aa)
PID1Phosphotyrosine interaction domain containing 1. (217 aa)
INHBBInhibin subunit beta B. (408 aa)
MKKSMcKusick-Kaufman syndrome. (573 aa)
LEPRLeptin receptor. (1166 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (730 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (192 aa)
MT3Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (68 aa)
LRP2LDL receptor related protein 2. (4649 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (616 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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