(49 nodes) Establishment or maintenance of epithelial cell apical/basal polarity network (Capra hircus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	SH3BP1	Uncharacterized protein. (601 aa)
	ERBIN	Erbb2 interacting protein. (1418 aa)
	TCF15	Transcription factor 15. (197 aa)
	PRKCI	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (636 aa)
	CRB2	Crumbs cell polarity complex component 2. (1275 aa)
	NT5DC3	5'-nucleotidase domain containing 3. (545 aa)
	SYNE4	KASH domain-containing protein. (284 aa)
	CDX2	Caudal type homeobox 2. (306 aa)
	CDC42	Uncharacterized protein. (191 aa)
	RHOA	Ras-like protein family member A. (193 aa)
	ENSCHIP00000011371	Uncharacterized protein. (193 aa)
	MSN	Moesin. (666 aa)
	LIN7C	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (201 aa)
	MYO9A	Myosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2630 aa)
	IFT20	Intraflagellar transport 20. (156 aa)
	SLC9A3R1	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (386 aa)
	DLG1	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (927 aa)
	ENSCHIP00000005724	Uncharacterized protein. (62 aa)
	LOC102176514	Uncharacterized protein. (182 aa)
	WDR1	WD repeat domain 1. (606 aa)
	DLG2	Discs large MAGUK scaffold protein 2. (901 aa)
	LHX2	Uncharacterized protein. (422 aa)
	LOC102175359	PDZ domain-containing protein. (136 aa)
	NT5DC2	5'-nucleotidase domain containing 2. (558 aa)
	MPP5	Membrane palmitoylated protein 5; Belongs to the MAGUK family. (675 aa)
	CRB1	Crumbs cell polarity complex component 1. (1409 aa)
	SYNJ2BP	Synaptojanin 2 binding protein. (145 aa)
	ENSCHIP00000024754	L27_1 domain-containing protein. (61 aa)
	WNT11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	LRRC1	Leucine rich repeat containing 1. (517 aa)
	PDZD11	PDZ domain-containing protein. (140 aa)
	ILK	Integrin linked kinase. (452 aa)
	FAT1	FAT atypical cadherin 1. (4643 aa)
	PTK7	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
	MARK2	Non-specific serine/threonine protein kinase. (787 aa)
	OPHN1	Oligophrenin 1. (436 aa)
	SCRIB	Scribble planar cell polarity protein. (1582 aa)
	PARD3	Par-3 family cell polarity regulator. (1351 aa)
	FOXF1	Forkhead box F1. (391 aa)
	LIN7B	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (207 aa)
	DLG3	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (836 aa)
	TTC8	Tetratricopeptide repeat domain 8. (511 aa)
	DLG5	Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1946 aa)
	ENSCHIP00000001541	PDZ domain-containing protein. (111 aa)
	LIN7A	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (233 aa)
	CAMSAP3	Calmodulin regulated spectrin associated protein family member 3. (1246 aa)
	PARD3B	Par-3 family cell polarity regulator beta. (1037 aa)
	PARD6A	Par-6 family cell polarity regulator alpha. (344 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	DLG5	ENSCHIP00000012064	ENSCHIP00000000553	Uncharacterized protein.	Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family.	0.460
CDC42	ENSCHIP00000011371	ENSCHIP00000012064	ENSCHIP00000011371	Uncharacterized protein.	Uncharacterized protein.	0.437
CDC42	ILK	ENSCHIP00000012064	ENSCHIP00000017722	Uncharacterized protein.	Integrin linked kinase.	0.758
CDC42	MPP5	ENSCHIP00000012064	ENSCHIP00000027790	Uncharacterized protein.	Membrane palmitoylated protein 5; Belongs to the MAGUK family.	0.435
CDC42	MSN	ENSCHIP00000012064	ENSCHIP00000010531	Uncharacterized protein.	Moesin.	0.780
CDC42	MYO9A	ENSCHIP00000012064	ENSCHIP00000008521	Uncharacterized protein.	Myosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.757
CDC42	OPHN1	ENSCHIP00000012064	ENSCHIP00000021448	Uncharacterized protein.	Oligophrenin 1.	0.682
CDC42	PARD3	ENSCHIP00000012064	ENSCHIP00000020604	Uncharacterized protein.	Par-3 family cell polarity regulator.	0.965
CDC42	PARD6A	ENSCHIP00000012064	ENSCHIP00000003736	Uncharacterized protein.	Par-6 family cell polarity regulator alpha.	0.990
CDC42	PRKCI	ENSCHIP00000012064	ENSCHIP00000032709	Uncharacterized protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.962
CDC42	RHOA	ENSCHIP00000012064	ENSCHIP00000011951	Uncharacterized protein.	Ras-like protein family member A.	0.963
CDC42	SCRIB	ENSCHIP00000012064	ENSCHIP00000020687	Uncharacterized protein.	Scribble planar cell polarity protein.	0.610
CDC42	SLC9A3R1	ENSCHIP00000012064	ENSCHIP00000007323	Uncharacterized protein.	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.	0.410
CRB1	CRB2	ENSCHIP00000027469	ENSCHIP00000032297	Crumbs cell polarity complex component 1.	Crumbs cell polarity complex component 2.	0.924
CRB1	LIN7C	ENSCHIP00000027469	ENSCHIP00000009784	Crumbs cell polarity complex component 1.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.621
CRB1	MPP5	ENSCHIP00000027469	ENSCHIP00000027790	Crumbs cell polarity complex component 1.	Membrane palmitoylated protein 5; Belongs to the MAGUK family.	0.895
CRB1	SCRIB	ENSCHIP00000027469	ENSCHIP00000020687	Crumbs cell polarity complex component 1.	Scribble planar cell polarity protein.	0.598
CRB2	CRB1	ENSCHIP00000032297	ENSCHIP00000027469	Crumbs cell polarity complex component 2.	Crumbs cell polarity complex component 1.	0.924
CRB2	LIN7C	ENSCHIP00000032297	ENSCHIP00000009784	Crumbs cell polarity complex component 2.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.402
CRB2	MPP5	ENSCHIP00000032297	ENSCHIP00000027790	Crumbs cell polarity complex component 2.	Membrane palmitoylated protein 5; Belongs to the MAGUK family.	0.520