STRINGSTRING
FLCN FLCN WDR1 WDR1 PRKCA PRKCA SNAI2 SNAI2 CTNND1 CTNND1 CLDN18 CLDN18 DLG2 DLG2 CDH11 CDH11 PTPRO PTPRO GJA5 GJA5 CLDN14 CLDN14 CLDN11 CLDN11 FLNA FLNA CDH9 CDH9 PKP3 PKP3 ILDR1 ILDR1 TGFB1 TGFB1 CLDN2 CLDN2 SRF SRF CDH24 CDH24 HDAC7 HDAC7 ENSCHIP00000009957 ENSCHIP00000009957 RHOB RHOB GNPAT GNPAT DCHS1 DCHS1 ENSCHIP00000010686 ENSCHIP00000010686 ACTB ACTB PLEKHA7 PLEKHA7 CTNND2 CTNND2 INAVA INAVA ENSCHIP00000011371 ENSCHIP00000011371 DSP DSP FSCN1 FSCN1 TRPV4 TRPV4 SMAD3 SMAD3 RHOA RHOA CDC42 CDC42 NF2 NF2 NPHS1 NPHS1 PRTN3 PRTN3 CDH12 CDH12 FRMPD2 FRMPD2 PKP2 PKP2 CLDN10 CLDN10 ENSCHIP00000013896 ENSCHIP00000013896 ARVCF ARVCF CDH6 CDH6 CDH5 CDH5 LSR LSR MARVELD2 MARVELD2 DSG2 DSG2 VCL VCL ENSCHIP00000000486 ENSCHIP00000000486 DLG5 DLG5 OCLN OCLN TGFB3 TGFB3 CLDN9 CLDN9 CLDN6 CLDN6 CLDN3 CLDN3 CLDN20 CLDN20 CLDN4 CLDN4 GJB2 GJB2 LOC102186369 LOC102186369 CTNNA1 CTNNA1 CAMSAP3 CAMSAP3 HIPK1 HIPK1 GJB6 GJB6 ADAM10 ADAM10 CLDN34 CLDN34 PARD6A PARD6A LOC102186657 LOC102186657 GJC1 GJC1 CLDN17 CLDN17 CD9 CD9 PKN2 PKN2 EXT1 EXT1 RAMP2 RAMP2 ENSCHIP00000005724 ENSCHIP00000005724 TJP2 TJP2 CDH19 CDH19 ENSCHIP00000006081 ENSCHIP00000006081 JAM3 JAM3 DLG1 DLG1 CDH7 CDH7 LIMS2 LIMS2 TJP1 TJP1 NUMB NUMB UGT8 UGT8 GRHL2 GRHL2 TJP3 TJP3 CLDN19 CLDN19 CDH1 CDH1 CDH8 CDH8 PKP4 PKP4 PAK2 PAK2 CD177 CD177 MPP7 MPP7 CDH2 CDH2 CDH22 CDH22 PECAM1 PECAM1 AJM1 AJM1 SMAD7 SMAD7 TBCD TBCD POF1B POF1B CLDN5 CLDN5 CCM2 CCM2 CLDN16 CLDN16 CDH18 CDH18 OCEL1 OCEL1 NR1H4 NR1H4 ARL2 ARL2 CLDN1 CLDN1 KIRREL1 KIRREL1 CNTNAP1 CNTNAP1 WNT11 WNT11 NUMBL NUMBL ZNF703 ZNF703 PKHD1 PKHD1 PLEC PLEC RAB13 RAB13 LIMS1 LIMS1 F2R F2R CXADR CXADR TGFB2 TGFB2 CSK CSK FBF1 FBF1 MTSS1 MTSS1 PKP1 PKP1 PATJ PATJ FERMT2 FERMT2 RHOC RHOC KIFC3 KIFC3 CDH10 CDH10 PARD6B PARD6B WHRN WHRN EPHA4 EPHA4 CLDN7 CLDN7 CTNNB1 CTNNB1 ECT2 ECT2 MARVELD3 MARVELD3 SVEP1 SVEP1 ENSCHIP00000031987 ENSCHIP00000031987 NECTIN1 NECTIN1 JUP JUP F2RL1 F2RL1 ESAM ESAM PRKCI PRKCI ACTG1 ACTG1 CSF1R CSF1R GRHL1 GRHL1 CDH20 CDH20 CLDN8 CLDN8 ENSCHIP00000033272 ENSCHIP00000033272
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FLCNUDENN FLCN/SMCR8-type domain-containing protein. (579 aa)
WDR1WD repeat domain 1. (606 aa)
PRKCAUncharacterized protein. (605 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
CTNND1Catenin delta 1. (939 aa)
CLDN18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa)
DLG2Discs large MAGUK scaffold protein 2. (901 aa)
CDH11Cadherin 11; Cadherins are calcium-dependent cell adhesion proteins. (796 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1216 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (359 aa)
CLDN14Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (233 aa)
CLDN11Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa)
FLNAFilamin A. (2647 aa)
CDH9Cadherin 9; Cadherins are calcium-dependent cell adhesion proteins. (789 aa)
PKP3Uncharacterized protein. (412 aa)
ILDR1Immunoglobulin like domain containing receptor 1. (548 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
CLDN2Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa)
SRFSerum response factor. (509 aa)
CDH24Cadherin 24; Cadherins are calcium-dependent cell adhesion proteins. (810 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1062 aa)
ENSCHIP00000009957Calponin-homology (CH) domain-containing protein. (123 aa)
RHOBRhoB. (196 aa)
GNPATDihydroxyacetone phosphate acyltransferase. (680 aa)
DCHS1Dachsous cadherin-related 1. (3258 aa)
ENSCHIP00000010686CCM2_C domain-containing protein. (440 aa)
ACTBUncharacterized protein. (375 aa)
PLEKHA7Pleckstrin homology domain containing A7. (1333 aa)
CTNND2Catenin delta 2. (1164 aa)
INAVAInnate immunity activator. (644 aa)
ENSCHIP00000011371Uncharacterized protein. (193 aa)
DSPDesmoplakin. (2892 aa)
FSCN1Fascin. (493 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
RHOARas-like protein family member A. (193 aa)
CDC42Uncharacterized protein. (191 aa)
NF2FERM domain-containing protein. (612 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1233 aa)
PRTN3Proteinase 3; Belongs to the peptidase S1 family. (256 aa)
CDH12Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
FRMPD2FERM and PDZ domain containing 2. (1379 aa)
PKP2Plakophilin 2. (851 aa)
CLDN10Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (231 aa)
ENSCHIP00000013896Uncharacterized protein. (179 aa)
ARVCFARVCF delta catenin family member. (955 aa)
CDH6Cadherin 6; Cadherins are calcium-dependent cell adhesion proteins. (790 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (783 aa)
LSRLipolysis stimulated lipoprotein receptor. (621 aa)
MARVELD2MARVEL domain containing 2. (551 aa)
DSG2Desmoglein 2. (1119 aa)
VCLVinculin. (1134 aa)
ENSCHIP00000000486Uncharacterized protein. (144 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1946 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (522 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (452 aa)
CLDN9Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
CLDN6Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa)
CLDN20Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa)
CLDN4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
GJB2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (226 aa)
LOC102186369Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
CTNNA1Catenin alpha 1. (1018 aa)
CAMSAP3Calmodulin regulated spectrin associated protein family member 3. (1246 aa)
HIPK1Homeodomain interacting protein kinase 1. (1210 aa)
GJB6Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (261 aa)
ADAM10ADAM metallopeptidase domain 10. (750 aa)
CLDN34Uncharacterized protein. (259 aa)
PARD6APar-6 family cell polarity regulator alpha. (344 aa)
LOC102186657Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
GJC1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (396 aa)
CLDN17Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa)
CD9Tetraspanin. (226 aa)
PKN2Protein kinase N2. (981 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (446 aa)
RAMP2Receptor activity modifying protein 2. (177 aa)
ENSCHIP00000005724Uncharacterized protein. (62 aa)
TJP2Uncharacterized protein; Belongs to the MAGUK family. (1151 aa)
CDH19Cadherin 19; Cadherins are calcium-dependent cell adhesion proteins. (770 aa)
ENSCHIP00000006081Uncharacterized protein. (72 aa)
JAM3Junctional adhesion molecule 3. (329 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (927 aa)
CDH7Cadherin 7; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (341 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1766 aa)
NUMBNUMB endocytic adaptor protein. (650 aa)
UGT8UDP glycosyltransferase 8; Belongs to the UDP-glycosyltransferase family. (541 aa)
GRHL2Grainyhead like transcription factor 2. (622 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (913 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (903 aa)
CDH8Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins. (799 aa)
PKP4Plakophilin 4. (1193 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
CD177CD177 molecule. (441 aa)
MPP7Membrane palmitoylated protein 7; Belongs to the MAGUK family. (576 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
CDH22Cadherin 22; Cadherins are calcium-dependent cell adhesion proteins. (873 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (739 aa)
AJM1Apical junction component 1 homolog. (975 aa)
SMAD7Mothers against decapentaplegic homolog. (427 aa)
TBCDTubulin folding cofactor D. (1200 aa)
POF1BPOF1B actin binding protein. (612 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
CCM2PID domain-containing protein. (476 aa)
CLDN16Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (254 aa)
CDH18Cadherin 18; Cadherins are calcium-dependent cell adhesion proteins. (790 aa)
OCEL1Occludin_ELL domain-containing protein. (171 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (486 aa)
ARL2ARL2-SNX15 readthrough (NMD candidate); Belongs to the small GTPase superfamily. Arf family. (184 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
KIRREL1Kirre like nephrin family adhesion molecule 1. (792 aa)
CNTNAP1Contactin associated protein 1. (1396 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
NUMBLNUMB like endocytic adaptor protein. (594 aa)
ZNF703Zinc finger protein 703. (588 aa)
PKHD1PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4040 aa)
PLECPlectin. (4150 aa)
RAB13Uncharacterized protein. (203 aa)
LIMS1LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (336 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
CXADRUncharacterized protein. (416 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
CSKTyrosine-protein kinase. (450 aa)
FBF1Fas binding factor 1. (1033 aa)
MTSS1MTSS I-BAR domain containing 1. (737 aa)
PKP1Plakophilin 1. (742 aa)
PATJPATJ crumbs cell polarity complex component. (1905 aa)
FERMT2Fermitin family member 2. (680 aa)
RHOCRas homolog family member C. (193 aa)
KIFC3Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (945 aa)
CDH10Cadherin 10; Cadherins are calcium-dependent cell adhesion proteins. (788 aa)
PARD6BPar-6 family cell polarity regulator beta. (373 aa)
WHRNWhirlin. (918 aa)
EPHA4EPH receptor A4. (986 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
CTNNB1Catenin beta 1. (781 aa)
ECT2Epithelial cell transforming 2. (913 aa)
MARVELD3MARVEL domain containing 3. (383 aa)
SVEP1Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1. (3559 aa)
ENSCHIP00000031987Non-specific serine/threonine protein kinase. (199 aa)
NECTIN1Nectin cell adhesion molecule 1. (515 aa)
JUPJunction plakoglobin. (745 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
ESAMEndothelial cell adhesion molecule. (396 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (636 aa)
ACTG1Actin gamma 1. (376 aa)
CSF1RColony stimulating factor 1 receptor. (958 aa)
GRHL1CP2 domain-containing protein. (617 aa)
CDH20Cadherin 20; Cadherins are calcium-dependent cell adhesion proteins. (801 aa)
CLDN8Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa)
ENSCHIP00000033272FERM domain-containing protein. (580 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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