(31 nodes) Late endosome to vacuole transport network (Capra hircus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	VTA1	Uncharacterized protein. (307 aa)
	ENSCHIP00000027249	Protein kinase domain-containing protein. (292 aa)
	CHMP7	Uncharacterized protein. (450 aa)
	LOC102188868	Uncharacterized protein. (222 aa)
	ENSCHIP00000030213	Vta1 domain-containing protein. (261 aa)
	CHMP1A	Charged multivesicular body protein 1A. (247 aa)
	TMEM50A	Transmembrane protein 50A. (157 aa)
	PIK3R4	Phosphoinositide-3-kinase regulatory subunit 4. (1310 aa)
	ENSCHIP00000032547	APG6 domain-containing protein. (249 aa)
	CHMP5	Charged multivesicular body protein 5. (219 aa)
	ENSCHIP00000000483	Uncharacterized protein. (304 aa)
	CHMP6	Charged multivesicular body protein 6. (213 aa)
	STAM	Signal transducing adaptor molecule. (534 aa)
	CHMP4C	Charged multivesicular body protein 4C. (236 aa)
	VPS36	Vacuolar protein sorting 36 homolog. (457 aa)
	PTPN23	Protein tyrosine phosphatase non-receptor type 23. (1617 aa)
	LEPROT	Leptin receptor overlapping transcript. (128 aa)
	CHMP2A	Charged multivesicular body protein 2A. (222 aa)
	ENSCHIP00000009861	Protein kinase domain-containing protein. (292 aa)
	TMEM50B	Transmembrane protein 50B. (158 aa)
	CHMP2B	Charged multivesicular body protein 2B. (226 aa)
	SNF8	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (262 aa)
	CHMP4B	Charged multivesicular body protein 4B. (224 aa)
	VPS25	Vacuolar protein sorting 25 homolog. (176 aa)
	LOC108635484	Protein kinase domain-containing protein. (677 aa)
	ENSCHIP00000020708	Protein kinase domain-containing protein. (969 aa)
	VPS28	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (221 aa)
	CHMP4A	Charged multivesicular body protein 4A. (222 aa)
	LEPROTL1	Leptin receptor overlapping transcript like 1. (134 aa)
	BECN1	Uncharacterized protein. (448 aa)
	LOC108635483	Uncharacterized protein. (156 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BECN1	ENSCHIP00000000483	ENSCHIP00000024304	ENSCHIP00000000483	Uncharacterized protein.	Uncharacterized protein.	0.793
BECN1	ENSCHIP00000009861	ENSCHIP00000024304	ENSCHIP00000009861	Uncharacterized protein.	Protein kinase domain-containing protein.	0.793
BECN1	ENSCHIP00000020708	ENSCHIP00000024304	ENSCHIP00000020708	Uncharacterized protein.	Protein kinase domain-containing protein.	0.793
BECN1	ENSCHIP00000027249	ENSCHIP00000024304	ENSCHIP00000027249	Uncharacterized protein.	Protein kinase domain-containing protein.	0.793
BECN1	LOC108635484	ENSCHIP00000024304	ENSCHIP00000019903	Uncharacterized protein.	Protein kinase domain-containing protein.	0.793
BECN1	PIK3R4	ENSCHIP00000024304	ENSCHIP00000031695	Uncharacterized protein.	Phosphoinositide-3-kinase regulatory subunit 4.	0.999
CHMP1A	CHMP2A	ENSCHIP00000030912	ENSCHIP00000007638	Charged multivesicular body protein 1A.	Charged multivesicular body protein 2A.	0.997
CHMP1A	CHMP2B	ENSCHIP00000030912	ENSCHIP00000012117	Charged multivesicular body protein 1A.	Charged multivesicular body protein 2B.	0.987
CHMP1A	CHMP4A	ENSCHIP00000030912	ENSCHIP00000022984	Charged multivesicular body protein 1A.	Charged multivesicular body protein 4A.	0.543
CHMP1A	CHMP4B	ENSCHIP00000030912	ENSCHIP00000014193	Charged multivesicular body protein 1A.	Charged multivesicular body protein 4B.	0.910
CHMP1A	CHMP4C	ENSCHIP00000030912	ENSCHIP00000002627	Charged multivesicular body protein 1A.	Charged multivesicular body protein 4C.	0.952
CHMP1A	CHMP5	ENSCHIP00000030912	ENSCHIP00000032770	Charged multivesicular body protein 1A.	Charged multivesicular body protein 5.	0.969
CHMP1A	CHMP6	ENSCHIP00000030912	ENSCHIP00000001486	Charged multivesicular body protein 1A.	Charged multivesicular body protein 6.	0.907
CHMP1A	CHMP7	ENSCHIP00000030912	ENSCHIP00000029662	Charged multivesicular body protein 1A.	Uncharacterized protein.	0.726
CHMP1A	ENSCHIP00000030213	ENSCHIP00000030912	ENSCHIP00000030213	Charged multivesicular body protein 1A.	Vta1 domain-containing protein.	0.879
CHMP1A	LOC102188868	ENSCHIP00000030912	ENSCHIP00000029770	Charged multivesicular body protein 1A.	Uncharacterized protein.	0.971
CHMP1A	LOC108635483	ENSCHIP00000030912	ENSCHIP00000024855	Charged multivesicular body protein 1A.	Uncharacterized protein.	0.567
CHMP1A	SNF8	ENSCHIP00000030912	ENSCHIP00000013350	Charged multivesicular body protein 1A.	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	0.839
CHMP1A	STAM	ENSCHIP00000030912	ENSCHIP00000002156	Charged multivesicular body protein 1A.	Signal transducing adaptor molecule.	0.500
CHMP1A	VPS25	ENSCHIP00000030912	ENSCHIP00000014718	Charged multivesicular body protein 1A.	Vacuolar protein sorting 25 homolog.	0.795