20 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108635823	AIG1-type G domain-containing protein. (297 aa)
	LOC102183503	AIG1-type G domain-containing protein. (309 aa)
	GIMAP5	AIG1-type G domain-containing protein. (298 aa)
	SOCS1	Suppressor of cytokine signaling 1. (219 aa)
	VSIR	V-set immunoregulatory receptor. (312 aa)
	IL2RG	Fibronectin type-III domain-containing protein. (378 aa)
	ENSCHIP00000003765	AIG1-type G domain-containing protein. (277 aa)
	SOX12	Transcription factor SOX. (314 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	IL4I1	Interleukin 4 induced 1. (582 aa)
	FOXP3	Forkhead box P3. (463 aa)
	KAT5	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
	IFNG	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (166 aa)
	AMBRA1	Autophagy and beclin 1 regulator 1. (1300 aa)
	FOXO3	Forkhead box O3. (672 aa)
	DUSP10	Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
	ENSCHIP00000022485	AIG1-type G domain-containing protein. (295 aa)
	LOC102183203	Amine oxidase. (517 aa)
	LOC102178618	AIG1-type G domain-containing protein. (214 aa)
	BCL6	BCL6 transcription repressor. (706 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL6	FOXP3	ENSCHIP00000032540	ENSCHIP00000012575	BCL6 transcription repressor.	Forkhead box P3.	0.913
BCL6	IFNG	ENSCHIP00000032540	ENSCHIP00000016152	BCL6 transcription repressor.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family.	0.741
BCL6	SOCS1	ENSCHIP00000032540	ENSCHIP00000001164	BCL6 transcription repressor.	Suppressor of cytokine signaling 1.	0.400
FOXP3	BCL6	ENSCHIP00000012575	ENSCHIP00000032540	Forkhead box P3.	BCL6 transcription repressor.	0.913
FOXP3	IFNG	ENSCHIP00000012575	ENSCHIP00000016152	Forkhead box P3.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family.	0.978
FOXP3	IL2RG	ENSCHIP00000012575	ENSCHIP00000002808	Forkhead box P3.	Fibronectin type-III domain-containing protein.	0.433
FOXP3	KAT5	ENSCHIP00000012575	ENSCHIP00000014439	Forkhead box P3.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.513
FOXP3	SOCS1	ENSCHIP00000012575	ENSCHIP00000001164	Forkhead box P3.	Suppressor of cytokine signaling 1.	0.521
FOXP3	TGFB1	ENSCHIP00000012575	ENSCHIP00000008885	Forkhead box P3.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.696
IFNG	BCL6	ENSCHIP00000016152	ENSCHIP00000032540	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family.	BCL6 transcription repressor.	0.741
IFNG	FOXP3	ENSCHIP00000016152	ENSCHIP00000012575	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family.	Forkhead box P3.	0.978
IFNG	IL2RG	ENSCHIP00000016152	ENSCHIP00000002808	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family.	Fibronectin type-III domain-containing protein.	0.827
IFNG	SOCS1	ENSCHIP00000016152	ENSCHIP00000001164	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family.	Suppressor of cytokine signaling 1.	0.922
IFNG	TGFB1	ENSCHIP00000016152	ENSCHIP00000008885	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.786
IL2RG	FOXP3	ENSCHIP00000002808	ENSCHIP00000012575	Fibronectin type-III domain-containing protein.	Forkhead box P3.	0.433
IL2RG	IFNG	ENSCHIP00000002808	ENSCHIP00000016152	Fibronectin type-III domain-containing protein.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family.	0.827
IL4I1	LOC102183203	ENSCHIP00000012465	ENSCHIP00000023188	Interleukin 4 induced 1.	Amine oxidase.	0.905
KAT5	FOXP3	ENSCHIP00000014439	ENSCHIP00000012575	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Forkhead box P3.	0.513
LOC102183203	IL4I1	ENSCHIP00000023188	ENSCHIP00000012465	Amine oxidase.	Interleukin 4 induced 1.	0.905
SOCS1	BCL6	ENSCHIP00000001164	ENSCHIP00000032540	Suppressor of cytokine signaling 1.	BCL6 transcription repressor.	0.400