STRINGSTRING
BMP7 BMP7 CCN1 CCN1 FBXO5 FBXO5 PPP3CA PPP3CA BMP6 BMP6 CEBPB CEBPB CTNNB1 CTNNB1 GDPD2 GDPD2 SOX11 SOX11 CLIC1 CLIC1 TENT5A TENT5A CTNNBIP1 CTNNBIP1 FERMT2 FERMT2 TP63 TP63 SCUBE3 SCUBE3 SFRP2 SFRP2 DDR2 DDR2 ZHX3 ZHX3 BMP4 BMP4 JAG1 JAG1 BMPR2 BMPR2 LRP5 LRP5 NPNT NPNT IGF1 IGF1 FGF2 FGF2 BMPR1B BMPR1B PRKD1 PRKD1 SCUBE2 SCUBE2 ILK ILK WWTR1 WWTR1 YAP1 YAP1 WDR63 WDR63 LTF LTF MEF2C MEF2C RUNX2 RUNX2 GLI3 GLI3 ATRAID ATRAID SMAD5 SMAD5 ENSCHIP00000012753 ENSCHIP00000012753 SUCO SUCO ACVR2A ACVR2A FBN2 FBN2 BMP2 BMP2 CTHRC1 CTHRC1 TMEM119 TMEM119 LRP3 LRP3 CCN4 CCN4 PDLIM7 PDLIM7 FFAR4 FFAR4 SMAD1 SMAD1 WNT10B WNT10B IL6ST IL6ST BMPR1A BMPR1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMP7Bone morphogenetic protein 7. (431 aa)
CCN1Cellular communication network factor 1. (382 aa)
FBXO5F-box protein 5. (448 aa)
PPP3CASerine/threonine-protein phosphatase. (527 aa)
BMP6Bone morphogenetic protein 6. (496 aa)
CEBPBCCAAT/enhancer-binding protein. (307 aa)
CTNNB1Catenin beta 1. (781 aa)
GDPD2Glycerophosphodiester phosphodiesterase domain containing 2. (513 aa)
SOX11Transcription factor SOX. (444 aa)
CLIC1Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (241 aa)
TENT5ATerminal nucleotidyltransferase 5A. (412 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
FERMT2Fermitin family member 2. (680 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (681 aa)
SCUBE3Signal peptide, CUB domain and EGF like domain containing 3. (936 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (889 aa)
ZHX3Zinc fingers and homeoboxes 3. (943 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1615 aa)
NPNTNephronectin. (606 aa)
IGF1Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (188 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (558 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (920 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (1022 aa)
ILKIntegrin linked kinase. (452 aa)
WWTR1WW domain containing transcription regulator 1. (419 aa)
YAP1Yes associated protein 1. (503 aa)
WDR63WD repeat domain 63. (892 aa)
LTFLactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. Shows a preferential cleavage at -Arg-Ser-Arg-Arg-|- and -Arg-Arg-Ser-Arg-|-, and of Z-Phe-Arg-|-aminomethylcoumarin sites. (754 aa)
MEF2CMADS-box domain-containing protein. (441 aa)
RUNX2RUNX family transcription factor 2. (585 aa)
GLI3GLI family zinc finger 3. (1614 aa)
ATRAIDAll-trans retinoic acid induced differentiation factor. (229 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
ENSCHIP00000012753Uncharacterized protein. (184 aa)
SUCOSUN domain containing ossification factor. (1254 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
FBN2Fibrillin 2. (2900 aa)
BMP2TGF_BETA_2 domain-containing protein. (381 aa)
CTHRC1Collagen triple helix repeat containing 1. (243 aa)
TMEM119Transmembrane protein 119. (284 aa)
LRP3LDL receptor related protein 3. (782 aa)
CCN4Cellular communication network factor 4. (368 aa)
PDLIM7PDZ and LIM domain 7. (508 aa)
FFAR4Free fatty acid receptor 4. (378 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
IL6STInterleukin 6 signal transducer. (918 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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