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| | SERPINF1 | Serpin family F member 1; Belongs to the serpin family. (416 aa) |
| | EPN2 | Epsin 2. (597 aa) |
| | AQP1 | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa) |
| | SULF1 | Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (868 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1843 aa) |
| | ENG | Endoglin. (649 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | TNMD | Tenomodulin. (318 aa) |
| | NODAL | Nodal growth differentiation factor. (346 aa) |
| | EMILIN2 | Elastin microfibril interfacer 2. (1076 aa) |
| | CCBE1 | Collagen and calcium binding EGF domains 1. (407 aa) |
| | JMJD8 | Jumonji domain containing 8. (344 aa) |
| | CHI3L1 | Chitinase-3-like protein 1; Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling [...] (391 aa) |
| | OR10J5 | Olfactory receptor family 10 subfamily J member 5. (309 aa) |
| | EFNA1 | Ephrin A1; Belongs to the ephrin family. (205 aa) |
| | HOXA5 | Homeobox A5. (270 aa) |
| | GPR4 | G protein-coupled receptor 4; Belongs to the G-protein coupled receptor 1 family. (362 aa) |
| | ECSCR | Uncharacterized protein. (253 aa) |
| | ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif 1. (971 aa) |
| | FKBPL | FKBP prolyl isomerase like. (345 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1390 aa) |
| | DAB2IP | DAB2 interacting protein. (1198 aa) |
| | E2F2 | E2F transcription factor 2. (437 aa) |
| | HSPB6 | Heat shock protein family B (small) member 6; Belongs to the small heat shock protein (HSP20) family. (164 aa) |
| | C3AR1 | Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family. (476 aa) |
| | CX3CR1 | C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (358 aa) |
| | PROK1 | Prokineticin 1. (105 aa) |
| | PDCD6 | Uncharacterized protein. (185 aa) |
| | IL17F | Uncharacterized protein. (178 aa) |
| | SPRY2 | Sprouty RTK signaling antagonist 2. (315 aa) |
| | C3 | Complement C3. (1663 aa) |
| | GTF2I | General transcription factor IIi. (999 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) |
| | KLF2 | Kruppel like factor 2. (361 aa) |
| | CREB3L1 | cAMP responsive element binding protein 3 like 1. (581 aa) |
| | PLXND1 | Plexin D1. (1926 aa) |
| | PML | Promyelocytic leukemia. (868 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (214 aa) |
| | RAMP2 | Receptor activity modifying protein 2. (177 aa) |
| | PDE3B | Phosphodiesterase. (1115 aa) |
| | CHRNA7 | Uncharacterized protein. (559 aa) |
| | PGK1 | Phosphoglycerate kinase. (424 aa) |
| | STAT1 | Signal transducer and activator of transcription. (834 aa) |
| | AGO2 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (860 aa) |
| | GREM1 | Gremlin. (184 aa) |
| | RAPGEF3 | Rap guanine nucleotide exchange factor 3. (924 aa) |
| | CCL24 | C-C motif chemokine ligand 24. (116 aa) |
| | NF1 | Neurofibromin 1. (2848 aa) |
| | ECM1 | Extracellular matrix protein 1. (524 aa) |
| | ITGB1 | Integrin beta; Belongs to the integrin beta chain family. (801 aa) |
| | SIRT1 | Deacetylase sirtuin-type domain-containing protein. (732 aa) |
| | C5 | Complement C5. (1675 aa) |
| | CELA1 | Chymotrypsin like elastase 1; Belongs to the peptidase S1 family. (266 aa) |
| | SPRED1 | Sprouty related EVH1 domain containing 1. (433 aa) |
| | IL1A | Interleukin-1 alpha; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity). (254 aa) |
| | SMAD1 | Mothers against decapentaplegic homolog. (465 aa) |
| | PTGIS | Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (503 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | TGFBR2 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (550 aa) |
| | ANXA3 | Annexin. (323 aa) |
| | ISM1 | Isthmin 1. (464 aa) |
| | EMP2 | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa) |
| | ENSCHIP00000008714 | Uncharacterized protein. (170 aa) |
| | CNMD | Chondromodulin. (335 aa) |
| | VASH2 | Vasohibin 2. (355 aa) |
| | AGO1 | Uncharacterized protein; Belongs to the argonaute family. (916 aa) |
| | S100A1 | Protein S100; Belongs to the S-100 family. (94 aa) |
| | EPN1 | Epsin 1. (576 aa) |
| | BTG1 | B-cell translocation protein 1. (171 aa) |
| | TBC1D31 | TBC1 domain family member 31. (1062 aa) |
| | PPP1R16B | Protein phosphatase 1 regulatory subunit 16B. (568 aa) |
| | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (539 aa) |
| | HK2 | Hexokinase 2. (917 aa) |
| | AGGF1 | Uncharacterized protein. (714 aa) |
| | JAK1 | Tyrosine-protein kinase. (1159 aa) |
| | SP1 | Uncharacterized protein. (786 aa) |
| | TSPAN12 | Tetraspanin. (305 aa) |
| | CCL11 | C-C motif chemokine. (97 aa) |
| | FOXO4 | Forkhead box O4. (535 aa) |
| | ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1384 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1193 aa) |
| | ENSCHIP00000011073 | Uncharacterized protein. (200 aa) |
| | PDCL3 | Phosducin like 3. (241 aa) |
| | TIE1 | Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1139 aa) |
| | JCAD | Junctional cadherin 5 associated. (1301 aa) |
| | ENSCHIP00000011638 | DUF1785 domain-containing protein. (242 aa) |
| | MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (780 aa) |
| | TEK | TEK receptor tyrosine kinase. (1125 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (308 aa) |
| | FUT2 | L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (339 aa) |
| | NAXE | NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (288 aa) |
| | SASH1 | SAM and SH3 domain containing 1. (1236 aa) |
| | ITGA5 | Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1100 aa) |
| | ADGRB3 | Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family. (1282 aa) |
| | CXCR3 | C-X-C chemokine receptor type 3; Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Binds to CCL21. Probably promotes cell chemotaxis response (By similarity). (367 aa) |
| | VASH1 | Vasohibin 1. (363 aa) |
| | PTPRM | Protein tyrosine phosphatase receptor type M. (1495 aa) |
| | PAK4 | Non-specific serine/threonine protein kinase. (584 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (557 aa) |
| | CXCL10 | C-X-C motif chemokine. (102 aa) |
| | CDH5 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (783 aa) |
| | EPHA2 | EPH receptor A2. (975 aa) |
| | CHGA | Chromogranin A. (534 aa) |
| | RNH1 | Ribonuclease/angiogenin inhibitor 1. (456 aa) |
| | HIF1A | Uncharacterized protein. (823 aa) |
| | EMC10 | ER membrane protein complex subunit 10. (262 aa) |
| | ETS1 | Uncharacterized protein. (485 aa) |
| | TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (918 aa) |
| | EGLN1 | Uncharacterized protein. (422 aa) |
| | HSPB1 | Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (201 aa) |
| | PKM | Pyruvate kinase; Belongs to the pyruvate kinase family. (531 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa) |
| | C5AR1 | Complement C5a receptor 1; Belongs to the G-protein coupled receptor 1 family. (352 aa) |
| | TNN | Tenascin N. (1384 aa) |
| | THBS2 | Thrombospondin 2. (1181 aa) |
| | HMOX1 | Heme oxygenase 1. (288 aa) |
| | MYDGF | Myeloid derived growth factor. (174 aa) |
| | LOC102170474 | Uncharacterized protein. (238 aa) |
| | RHOJ | Ras homolog family member J. (236 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | ADGRA2 | Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1335 aa) |
| | LRG1 | Leucine rich alpha-2-glycoprotein 1. (353 aa) |
| | ZNF304 | Zinc finger protein 304. (662 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (920 aa) |
| | THBS1 | Thrombospondin 1. (1218 aa) |
| | DCN | Decorin; May affect the rate of fibrils formation. (360 aa) |
| | SEMA6A | Semaphorin 6A; Belongs to the semaphorin family. (1046 aa) |
| | GDF2 | Growth differentiation factor 2. (430 aa) |
| | ANGPT4 | Angiopoietin 4. (498 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa) |
| | ANGPTL3 | Fibrinogen C-terminal domain-containing protein. (459 aa) |
| | ENPP2 | Ectonucleotide pyrophosphatase/phosphodiesterase 2. (884 aa) |
| | BMPER | BMP binding endothelial regulator. (685 aa) |
| | GATA6 | GATA binding protein 6. (592 aa) |
| | ADGRB1 | Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1560 aa) |
| | ANGPT2 | Angiopoietin 2. (498 aa) |
| | ENSCHIP00000020611 | Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (291 aa) |
| | ITGB8 | Integrin beta; Belongs to the integrin beta chain family. (772 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1337 aa) |
| | SARS1 | Seryl-tRNA synthetase. (514 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (192 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | FUT1 | L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (348 aa) |
| | SEMA3E | Semaphorin 3E; Belongs to the semaphorin family. (775 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | CLDN5 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) |
| | EMILIN1 | Elastin microfibril interfacer 1. (1017 aa) |
| | MTDH | Metadherin. (583 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | NR2E1 | Nuclear receptor subfamily 2 group E member 1. (385 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa) |
| | SERPINE1 | Serpin family E member 1; Belongs to the serpin family. (402 aa) |
| | FOXJ2 | Forkhead box J2. (561 aa) |
| | SPARC | Osteonectin. (303 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1228 aa) |
| | PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa) |
| | EPHA1 | EPH receptor A1. (968 aa) |
| | SPHK1 | Sphingosine kinase 1. (392 aa) |
| | ABL1 | Tyrosine-protein kinase. (1151 aa) |
| | LOC102176524 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1242 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (599 aa) |
| | PGF | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. (140 aa) |
| | RECK | Reversion inducing cysteine rich protein with kazal motifs. (971 aa) |
| | SYNJ2BP | Synaptojanin 2 binding protein. (145 aa) |
| | ISL1 | ISL LIM homeobox 1. (349 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | FASLG | FasL; Belongs to the tumor necrosis factor family. (277 aa) |
| | SEMA4A | Semaphorin 4A; Belongs to the semaphorin family. (762 aa) |
| | SFRP2 | Secreted frizzled related protein 2. (294 aa) |
| | ALOX5 | Arachidonate 5-lipoxygenase. (674 aa) |
| | MECP2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (481 aa) |
| | ENSCHIP00000027082 | Uncharacterized protein. (731 aa) |
| | EFNA3 | Ephrin RBD domain-containing protein; Belongs to the ephrin family. (232 aa) |
| | HYAL1 | Hyaluronidase. (450 aa) |
| | XBP1 | BZIP domain-containing protein. (261 aa) |
| | APLNR | Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa) |
| | VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa) |
| | WARS1 | Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (482 aa) |
| | KRIT1 | Uncharacterized protein. (736 aa) |
| | AAMP | Angio associated migratory cell protein. (435 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa) |
| | LOC102175359 | PDZ domain-containing protein. (136 aa) |
| | CD40 | CD40 molecule. (280 aa) |
| | PRKCA | Uncharacterized protein. (605 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |
| | APOH | Apolipoprotein H. (355 aa) |
| | APELA | Uncharacterized protein. (54 aa) |
| | ENSCHIP00000029391 | Uncharacterized protein. (179 aa) |
| | THBS4 | Thrombospondin 4. (965 aa) |
| | GAB1 | GRB2 associated binding protein 1. (751 aa) |
| | ACVRL1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) |
| | VEGFB | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (197 aa) |
| | SMOC2 | SPARC related modular calcium binding 2. (445 aa) |
| | HTATIP2 | HIV-1 Tat interactive protein 2. (242 aa) |
| | PIK3R6 | Phosphoinositide-3-kinase regulatory subunit 6. (762 aa) |
| | ADGRB2 | Adhesion G protein-coupled receptor B2; Belongs to the G-protein coupled receptor 2 family. (1560 aa) |
| | RRAS | RAS related. (218 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | HGS | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa) |
| | MINAR1 | Membrane integral NOTCH2 associated receptor 1. (917 aa) |
| | GLUL | Glutamine synthetase. (373 aa) |
| | HRG | Histidine rich glycoprotein. (531 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | SIRT6 | Sirtuin 6. (335 aa) |
| | PLK2 | Serine/threonine-protein kinase PLK. (685 aa) |
| | CTSH | Cathepsin H; Belongs to the peptidase C1 family. (335 aa) |
| | ENSCHIP00000031987 | Non-specific serine/threonine protein kinase. (199 aa) |
| | COL4A2 | Collagen type IV alpha 2 chain. (1607 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | JUP | Junction plakoglobin. (745 aa) |
