42 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ZRANB3	Zinc finger RANBP2-type containing 3. (1070 aa)
	NDFIP1	Nedd4 family interacting protein 1. (221 aa)
	TERF2	Telomeric repeat binding factor 2. (543 aa)
	PARPBP	PARP1 binding protein. (580 aa)
	MSH2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (946 aa)
	H1-2	Histone cluster 1 H1 family member c. (227 aa)
	RADX	RPA1 related single stranded DNA binding protein, X-linked. (764 aa)
	RMI2	Uncharacterized protein. (161 aa)
	KLHL15	Kelch like family member 15. (604 aa)
	FANCB	Uncharacterized protein. (447 aa)
	PARP3	Poly [ADP-ribose] polymerase. (525 aa)
	FBH1	F-box DNA helicase 1. (1048 aa)
	MAGEF1	MAGE family member F1. (299 aa)
	CGAS	Cyclic GMP-AMP synthase. (511 aa)
	RIF1	Replication timing regulatory factor 1. (2486 aa)
	TERF2IP	Uncharacterized protein. (400 aa)
	SHLD2	Shieldin complex subunit 2. (918 aa)
	SMCHD1	Structural maintenance of chromosomes flexible hinge domain containing 1. (1987 aa)
	FOXP3	Forkhead box P3. (463 aa)
	SHLD1	Shieldin complex subunit 1. (206 aa)
	H1-5	Histone cluster 1 H1 family member b. (226 aa)
	H1-4	Histone cluster 1 H1 family member e. (219 aa)
	RECQL5	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (991 aa)
	ENSCHIP00000006184	Uncharacterized protein. (96 aa)
	TP53BP1	Tumor protein p53 binding protein 1. (1966 aa)
	H1-6	Histone cluster 1 H1 family member t. (210 aa)
	H1-3	Histone cluster 1 H1 family member d. (221 aa)
	THOC1	THO complex 1. (657 aa)
	BLM	BLM RecQ like helicase. (1429 aa)
	MAD2L2	Mitotic arrest deficient 2 like 2. (195 aa)
	LOC102181348	H15 domain-containing protein. (210 aa)
	LOC102188481	Uncharacterized protein. (379 aa)
	UBQLN4	Ubiquilin 4. (601 aa)
	H1-8	H1 histone family member O oocyte specific. (333 aa)
	H1-1	Histone cluster 1 H1 family member a. (218 aa)
	POLQ	DNA polymerase theta. (2587 aa)
	RTEL1	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1212 aa)
	MSH6	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1361 aa)
	HELB	DNA helicase B. (1077 aa)
	MSH3	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1119 aa)
	BCL6	BCL6 transcription repressor. (706 aa)
	ENSCHIP00000031621	Uncharacterized protein. (159 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL6	FOXP3	ENSCHIP00000032540	ENSCHIP00000012575	BCL6 transcription repressor.	Forkhead box P3.	0.913
BLM	ENSCHIP00000031621	ENSCHIP00000006552	ENSCHIP00000031621	BLM RecQ like helicase.	Uncharacterized protein.	0.983
BLM	FBH1	ENSCHIP00000006552	ENSCHIP00000015825	BLM RecQ like helicase.	F-box DNA helicase 1.	0.809
BLM	HELB	ENSCHIP00000006552	ENSCHIP00000033771	BLM RecQ like helicase.	DNA helicase B.	0.503
BLM	MSH2	ENSCHIP00000006552	ENSCHIP00000025009	BLM RecQ like helicase.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.711
BLM	MSH3	ENSCHIP00000006552	ENSCHIP00000032746	BLM RecQ like helicase.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.539
BLM	MSH6	ENSCHIP00000006552	ENSCHIP00000012330	BLM RecQ like helicase.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.898
BLM	POLQ	ENSCHIP00000006552	ENSCHIP00000011845	BLM RecQ like helicase.	DNA polymerase theta.	0.739
BLM	RIF1	ENSCHIP00000006552	ENSCHIP00000022306	BLM RecQ like helicase.	Replication timing regulatory factor 1.	0.551
BLM	RMI2	ENSCHIP00000006552	ENSCHIP00000024473	BLM RecQ like helicase.	Uncharacterized protein.	0.983
BLM	RTEL1	ENSCHIP00000006552	ENSCHIP00000012311	BLM RecQ like helicase.	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	0.797
BLM	SHLD2	ENSCHIP00000006552	ENSCHIP00000000332	BLM RecQ like helicase.	Shieldin complex subunit 2.	0.527
BLM	TERF2	ENSCHIP00000006552	ENSCHIP00000029421	BLM RecQ like helicase.	Telomeric repeat binding factor 2.	0.564
BLM	TP53BP1	ENSCHIP00000006552	ENSCHIP00000006382	BLM RecQ like helicase.	Tumor protein p53 binding protein 1.	0.839
ENSCHIP00000031621	BLM	ENSCHIP00000031621	ENSCHIP00000006552	Uncharacterized protein.	BLM RecQ like helicase.	0.983
ENSCHIP00000031621	POLQ	ENSCHIP00000031621	ENSCHIP00000011845	Uncharacterized protein.	DNA polymerase theta.	0.478
ENSCHIP00000031621	RECQL5	ENSCHIP00000031621	ENSCHIP00000005703	Uncharacterized protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.662
ENSCHIP00000031621	RMI2	ENSCHIP00000031621	ENSCHIP00000024473	Uncharacterized protein.	Uncharacterized protein.	0.900
ENSCHIP00000031621	RTEL1	ENSCHIP00000031621	ENSCHIP00000012311	Uncharacterized protein.	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	0.514
FANCB	POLQ	ENSCHIP00000014817	ENSCHIP00000011845	Uncharacterized protein.	DNA polymerase theta.	0.487