STRINGSTRING
ENSCHIP00000024633 ENSCHIP00000024633 IL13 IL13 SYT10 SYT10 SDC1 SDC1 SCAMP5 SCAMP5 CD177 CD177 STXBP1 STXBP1 FGA FGA CFTR CFTR CACNA1H CACNA1H RAB2B RAB2B HYAL3 HYAL3 CACNA1A CACNA1A CADPS-2 CADPS-2 VAMP8 VAMP8 ADORA2B ADORA2B RAB27B RAB27B FGR FGR CADPS CADPS FGB FGB SNF8 SNF8 FGG FGG RAB3D RAB3D ITGAM ITGAM SNX4 SNX4 TSG101 TSG101 CACNB4 CACNB4 SYT2 SYT2 SLC4A8 SLC4A8 CDK5R2 CDK5R2 SNCA SNCA SYK SYK VPS4A VPS4A STX1A STX1A CHMP2A CHMP2A ATP13A2 ATP13A2 STXBP5 STXBP5 RAB27A RAB27A CNR1 CNR1 RAB3A RAB3A AP1G1 AP1G1 VSNL1 VSNL1 CACNA1B CACNA1B STAM STAM VPS4B VPS4B SPHK2 SPHK2 PLA2G3 PLA2G3 ENSCHIP00000030308 ENSCHIP00000030308 HGS HGS RAB15 RAB15 ENSCHIP00000030683 ENSCHIP00000030683 RAB5A RAB5A CDK5 CDK5 F2RL1 F2RL1 KIAA0100 KIAA0100 NLGN1 NLGN1 VAMP7 VAMP7 LAMP1 LAMP1 SYTL4 SYTL4 RAB7A RAB7A RAB9A RAB9A CACNB2 CACNB2 SYT1 SYT1 UNC13D UNC13D EXPH5 EXPH5 CADPS2 CADPS2 CACNA1I CACNA1I ZP3 ZP3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSCHIP00000024633UEV domain-containing protein. (323 aa)
IL13Interleukin 13. (131 aa)
SYT10Synaptotagmin 10. (523 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (312 aa)
SCAMP5Secretory carrier-associated membrane protein. (235 aa)
CD177CD177 molecule. (441 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (594 aa)
FGAFibrinogen alpha chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it [...] (618 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1524 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (1453 aa)
RAB2BUncharacterized protein. (216 aa)
HYAL3Hyaluronidase. (419 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2487 aa)
CADPS-2Uncharacterized protein. (153 aa)
VAMP8Vesicle associated membrane protein 8. (101 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (332 aa)
RAB27BRAB27B, member RAS oncogene family. (218 aa)
FGRTyrosine-protein kinase. (527 aa)
CADPSUncharacterized protein. (771 aa)
FGBFibrinogen beta chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it i [...] (494 aa)
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (262 aa)
FGGFibrinogen gamma chain. (442 aa)
RAB3DRAB3D, member RAS oncogene family. (219 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1152 aa)
SNX4Sorting nexin 4. (450 aa)
TSG101Uncharacterized protein. (391 aa)
CACNB4SH3 domain-containing protein. (505 aa)
SYT2Synaptotagmin 2. (417 aa)
SLC4A8Anion exchange protein. (1082 aa)
CDK5R2Cyclin-dependent kinase 5 activator. (373 aa)
SNCAAlpha-synuclein; Belongs to the synuclein family. (140 aa)
SYKSpleen associated tyrosine kinase. (636 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (442 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (288 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
ATP13A2ATPase cation transporting 13A2. (1035 aa)
STXBP5Syntaxin binding protein 5. (1152 aa)
RAB27ARAB27A, member RAS oncogene family. (221 aa)
CNR1Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (472 aa)
RAB3ARAB3A, member RAS oncogene family. (228 aa)
AP1G1AP-1 complex subunit gamma. (822 aa)
VSNL1Visinin like 1. (191 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2358 aa)
STAMSignal transducing adaptor molecule. (534 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (444 aa)
SPHK2Sphingosine kinase 2. (653 aa)
PLA2G3Phospholipase A2 group III. (509 aa)
ENSCHIP00000030308Uncharacterized protein. (155 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
RAB15RAB15, member RAS oncogene family. (212 aa)
ENSCHIP00000030683Uncharacterized protein. (66 aa)
RAB5AUncharacterized protein. (215 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
KIAA0100KIAA0100. (2241 aa)
NLGN1Neuroligin 1. (509 aa)
VAMP7Vesicle associated membrane protein 7; Belongs to the synaptobrevin family. (220 aa)
LAMP1Lysosomal associated membrane protein 1. (409 aa)
SYTL4Synaptotagmin like 4. (670 aa)
RAB7AUncharacterized protein. (207 aa)
RAB9ARAB9A, member RAS oncogene family. (203 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (613 aa)
SYT1Synaptotagmin 1. (441 aa)
UNC13DUnc-13 homolog D. (1086 aa)
EXPH5Exophilin 5. (2023 aa)
CADPS2Calcium dependent secretion activator 2. (1262 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2185 aa)
ZP3ZP domain-containing protein. (432 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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