STRINGSTRING
CFL1 CFL1 TENM4 TENM4 RAB14 RAB14 CRB2 CRB2 NFE2L2 NFE2L2 CTNNB1 CTNNB1 TFPT TFPT RUVBL2 RUVBL2 PAFAH1B1 PAFAH1B1 KAT14 KAT14 HESX1 HESX1 NOCT NOCT WDR5 WDR5 SFRP2 SFRP2 NLRP5 NLRP5 LHX1 LHX1 NOTCH1 NOTCH1 KAT2A KAT2A KHDC3L KHDC3L JAG1 JAG1 SOX17 SOX17 NFRKB NFRKB DLL1 DLL1 MBIP MBIP PHLDB1 PHLDB1 OSR1 OSR1 TADA2A TADA2A LAMA4 LAMA4 RUVBL1 RUVBL1 MCRS1 MCRS1 WNT1 WNT1 ENSCHIP00000018563 ENSCHIP00000018563 HES1 HES1 ENSCHIP00000018299 ENSCHIP00000018299 ENSCHIP00000017929 ENSCHIP00000017929 INO80E INO80E DHX36 DHX36 HNF4A HNF4A B4GALT5 B4GALT5 ACTL6A ACTL6A PHLDB2 PHLDB2 ZZZ3 ZZZ3 WNT3A WNT3A DAG1 DAG1 RACK1 RACK1 TGIF2 TGIF2 ACTR8 ACTR8 SGF29 SGF29 RBM19 RBM19 INSR INSR SEPTIN7 SEPTIN7 LAMA3 LAMA3 YEATS2 YEATS2 YY1 YY1 TRIP12 TRIP12 POGLUT1 POGLUT1 TADA3 TADA3 OTX2 OTX2 NIPBL NIPBL PHLDA2 PHLDA2 LAMA2 LAMA2 WNT2 WNT2 INO80D INO80D EHMT1 EHMT1 INO80 INO80 RACGAP1 RACGAP1 BAG6 BAG6 WNT2B WNT2B NR2C2 NR2C2 ENSCHIP00000003109 ENSCHIP00000003109 UCHL5 UCHL5 PHLDB3 PHLDB3 NODAL NODAL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (165 aa)
TENM4Teneurin transmembrane protein 4. (2855 aa)
RAB14Uncharacterized protein. (215 aa)
CRB2Crumbs cell polarity complex component 2. (1275 aa)
NFE2L2Nuclear factor erythroid 2-related factor 2. (616 aa)
CTNNB1Catenin beta 1. (781 aa)
TFPTTCF3 fusion partner. (254 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (471 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
KAT14Lysine acetyltransferase 14. (774 aa)
HESX1HESX homeobox 1. (185 aa)
NOCTNocturnin. (530 aa)
WDR5WD repeat domain 5. (334 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
NLRP5Uncharacterized protein. (1046 aa)
LHX1LIM homeobox 1. (406 aa)
NOTCH1Notch receptor 1. (2508 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
KHDC3LMOEP19 domain-containing protein. (325 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
SOX17SRY-box transcription factor 17. (410 aa)
NFRKBNuclear factor related to kappaB binding protein. (1298 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa)
MBIPMAP3K12 binding inhibitory protein 1. (344 aa)
PHLDB1Pleckstrin homology like domain family B member 1. (1369 aa)
OSR1Odd-skipped related transcription factor 1. (267 aa)
TADA2ATranscriptional adapter. (443 aa)
LAMA4Laminin subunit alpha 4. (1824 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
MCRS1Microspherule protein 1. (462 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
ENSCHIP00000018563SANT domain-containing protein. (124 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
ENSCHIP00000018299Homeobox domain-containing protein. (249 aa)
ENSCHIP00000017929Uncharacterized protein. (84 aa)
INO80EINO80 complex subunit E. (241 aa)
DHX36DEAH-box helicase 36. (1010 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (486 aa)
B4GALT5Beta-1,4-galactosyltransferase 5. (388 aa)
ACTL6AActin like 6A; Belongs to the actin family. (458 aa)
PHLDB2Pleckstrin homology like domain family B member 2. (1253 aa)
ZZZ3Uncharacterized protein. (910 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
DAG1Dystroglycan 1. (895 aa)
RACK1Receptor for activated C kinase 1. (317 aa)
TGIF2TGFB induced factor homeobox 2. (237 aa)
ACTR8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa)
SGF29SAGA complex associated factor 29. (293 aa)
RBM19RNA binding motif protein 19. (986 aa)
INSRTyrosine-protein kinase receptor. (1365 aa)
SEPTIN7Septin 7; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (436 aa)
LAMA3Laminin subunit alpha 3. (3339 aa)
YEATS2YEATS domain containing 2. (1412 aa)
YY1YY1 transcription factor. (415 aa)
TRIP12Thyroid hormone receptor interactor 12. (2067 aa)
POGLUT1Protein O-glucosyltransferase 1. (392 aa)
TADA3Transcriptional adaptor 3. (432 aa)
OTX2Homeobox domain-containing protein. (289 aa)
NIPBLNipped-B protein. (2804 aa)
PHLDA2Pleckstrin homology like domain family A member 2. (128 aa)
LAMA2Laminin subunit alpha 2. (3116 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
INO80DINO80 complex subunit D. (1026 aa)
EHMT1Euchromatic histone lysine methyltransferase 1. (1293 aa)
INO80INO80 complex ATPase subunit. (1566 aa)
RACGAP1Rac GTPase activating protein 1. (632 aa)
BAG6BCL2 associated athanogene 6. (1164 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (394 aa)
NR2C2Nuclear receptor subfamily 2 group C member 2. (629 aa)
ENSCHIP00000003109WD_REPEATS_REGION domain-containing protein. (59 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (325 aa)
PHLDB3Pleckstrin homology like domain family B member 3. (641 aa)
NODALNodal growth differentiation factor. (346 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.