STRINGSTRING
ITPKC ITPKC GBA GBA PPIP5K2 PPIP5K2 PTS PTS IP6K1 IP6K1 TMEM130 TMEM130 LOC108634131 LOC108634131 CYP27A1 CYP27A1 PCK2 PCK2 GOT1 GOT1 SPHK2 SPHK2 SPR SPR ENSCHIP00000028513 ENSCHIP00000028513 PCBD2 PCBD2 ACER2 ACER2 ISYNA1 ISYNA1 IMPA2 IMPA2 CYP27C1 CYP27C1 SPTLC2 SPTLC2 ENSCHIP00000024573 ENSCHIP00000024573 SPHK1 SPHK1 PCBD1 PCBD1 IP6K3 IP6K3 ENSCHIP00000021405 ENSCHIP00000021405 GCH1 GCH1 FGF2 FGF2 IPMK IPMK PLCG2 PLCG2 SPTLC1 SPTLC1 IP6K2 IP6K2 ITPKB ITPKB DHFR DHFR IMPA1 IMPA1 ASAH2 ASAH2 LOC102169668 LOC102169668 CYP2R1 CYP2R1 ENSCHIP00000012256 ENSCHIP00000012256 PGP PGP ACER3 ACER3 ITPKA ITPKA PTAFR PTAFR QDPR QDPR CYP27B1 CYP27B1 ASAH1 ASAH1 SPTSSB SPTSSB SPTSSA SPTSSA IPPK IPPK ACER1 ACER1 PPIP5K1 PPIP5K1 SPTLC3 SPTLC3 IP6K2-2 IP6K2-2 LOC102175036 LOC102175036 PCK1 PCK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITPKCKinase; Belongs to the inositol phosphokinase (IPK) family. (676 aa)
GBAGlucosylceramidase. (536 aa)
PPIP5K2Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1249 aa)
PTS6-pyruvoyl tetrahydrobiopterin synthase. (145 aa)
IP6K1Kinase; Belongs to the inositol phosphokinase (IPK) family. (424 aa)
TMEM130Transmembrane protein 130. (435 aa)
LOC108634131Uncharacterized protein. (125 aa)
CYP27A1Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (537 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
GOT1Aspartate aminotransferase. (413 aa)
SPHK2Sphingosine kinase 2. (653 aa)
SPRSepiapterin reductase. (267 aa)
ENSCHIP00000028513Uncharacterized protein. (129 aa)
PCBD2Pterin-4 alpha-carbinolamine dehydratase 2. (130 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
ISYNA1Inositol-3-phosphate synthase 1. (557 aa)
IMPA2Inositol-1-monophosphatase. (288 aa)
CYP27C1Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family. (372 aa)
SPTLC2Serine palmitoyltransferase long chain base subunit 2. (562 aa)
ENSCHIP00000024573Uncharacterized protein. (60 aa)
SPHK1Sphingosine kinase 1. (392 aa)
PCBD1Pterin-4 alpha-carbinolamine dehydratase 1. (104 aa)
IP6K3Kinase; Belongs to the inositol phosphokinase (IPK) family. (388 aa)
ENSCHIP00000021405DHFR domain-containing protein. (156 aa)
GCH1GTP cyclohydrolase 1. (248 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
IPMKKinase; Belongs to the inositol phosphokinase (IPK) family. (419 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa)
SPTLC1Serine palmitoyltransferase long chain base subunit 1. (480 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (448 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (942 aa)
DHFRDHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa)
IMPA1Inositol-1-monophosphatase. (277 aa)
ASAH2Neutral ceramidase. (770 aa)
LOC102169668DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (188 aa)
CYP2R1Cytochrome P450 family 2 subfamily R member 1; Belongs to the cytochrome P450 family. (501 aa)
ENSCHIP00000012256Uncharacterized protein. (94 aa)
PGPPhosphoglycolate phosphatase; Belongs to the HAD-like hydrolase superfamily. (323 aa)
ACER3Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (223 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (461 aa)
PTAFRPlatelet-activating factor receptor; Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system (By similarity). (352 aa)
QDPRQuinoid dihydropteridine reductase. (242 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
ASAH1N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (400 aa)
SPTSSBSerine palmitoyltransferase small subunit B. (76 aa)
SPTSSAUncharacterized protein. (106 aa)
IPPKInositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (491 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa)
PPIP5K1Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1477 aa)
SPTLC3Serine palmitoyltransferase long chain base subunit 3. (549 aa)
IP6K2-2Kinase; Belongs to the inositol phosphokinase (IPK) family. (163 aa)
LOC102175036Uncharacterized protein. (68 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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