16 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RARB	Retinoic acid receptor beta. (448 aa)
	CRKL	CRK like proto-oncogene, adaptor protein. (302 aa)
	PML	Promyelocytic leukemia. (868 aa)
	SNW1	SNW domain containing 1. (536 aa)
	RXRB	Retinoid X receptor beta. (533 aa)
	ACTN4	Actinin alpha 4. (933 aa)
	NR1D2	Nuclear receptor subfamily 1 group D member 2. (578 aa)
	RARA	Retinoic acid receptor alpha. (462 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
	CYP26B1	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
	ESRRG	Estrogen related receptor gamma. (442 aa)
	RARG	Retinoic acid receptor gamma. (458 aa)
	RXRA	NR LBD domain-containing protein. (106 aa)
	PTF1A	Pancreas associated transcription factor 1a. (325 aa)
	ALDH1A2	Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa)
	RXRG	Retinoid X receptor gamma. (539 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDH1A2	CYP26B1	ENSCHIP00000031730	ENSCHIP00000017046	Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family.	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family.	0.965
CYP26B1	ALDH1A2	ENSCHIP00000017046	ENSCHIP00000031730	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family.	Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family.	0.965
CYP26B1	RARB	ENSCHIP00000017046	ENSCHIP00000008820	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family.	Retinoic acid receptor beta.	0.538
CYP26B1	RARG	ENSCHIP00000017046	ENSCHIP00000027743	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family.	Retinoic acid receptor gamma.	0.546
NR1D2	PPARG	ENSCHIP00000011705	ENSCHIP00000015163	Nuclear receptor subfamily 1 group D member 2.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.603
NR1D2	RARA	ENSCHIP00000011705	ENSCHIP00000013234	Nuclear receptor subfamily 1 group D member 2.	Retinoic acid receptor alpha.	0.546
NR1D2	RARB	ENSCHIP00000011705	ENSCHIP00000008820	Nuclear receptor subfamily 1 group D member 2.	Retinoic acid receptor beta.	0.546
NR1D2	RARG	ENSCHIP00000011705	ENSCHIP00000027743	Nuclear receptor subfamily 1 group D member 2.	Retinoic acid receptor gamma.	0.546
NR1D2	RXRA	ENSCHIP00000011705	ENSCHIP00000028697	Nuclear receptor subfamily 1 group D member 2.	NR LBD domain-containing protein.	0.447
NR1D2	RXRB	ENSCHIP00000011705	ENSCHIP00000006437	Nuclear receptor subfamily 1 group D member 2.	Retinoid X receptor beta.	0.436
NR1D2	RXRG	ENSCHIP00000011705	ENSCHIP00000032925	Nuclear receptor subfamily 1 group D member 2.	Retinoid X receptor gamma.	0.436
PML	RARA	ENSCHIP00000004847	ENSCHIP00000013234	Promyelocytic leukemia.	Retinoic acid receptor alpha.	0.964
PML	RARB	ENSCHIP00000004847	ENSCHIP00000008820	Promyelocytic leukemia.	Retinoic acid receptor beta.	0.418
PML	RARG	ENSCHIP00000004847	ENSCHIP00000027743	Promyelocytic leukemia.	Retinoic acid receptor gamma.	0.418
PPARG	NR1D2	ENSCHIP00000015163	ENSCHIP00000011705	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Nuclear receptor subfamily 1 group D member 2.	0.603
PPARG	RXRA	ENSCHIP00000015163	ENSCHIP00000028697	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	NR LBD domain-containing protein.	0.999
PPARG	RXRB	ENSCHIP00000015163	ENSCHIP00000006437	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Retinoid X receptor beta.	0.980
PPARG	RXRG	ENSCHIP00000015163	ENSCHIP00000032925	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Retinoid X receptor gamma.	0.986
RARA	NR1D2	ENSCHIP00000013234	ENSCHIP00000011705	Retinoic acid receptor alpha.	Nuclear receptor subfamily 1 group D member 2.	0.546
RARA	PML	ENSCHIP00000013234	ENSCHIP00000004847	Retinoic acid receptor alpha.	Promyelocytic leukemia.	0.964