STRINGSTRING
LOC102171353 LOC102171353 SCARF2 SCARF2 PGRMC1 PGRMC1 B4GALT6 B4GALT6 GDF11 GDF11 LOC102191748 LOC102191748 LOC100861170 LOC100861170 GJA1 GJA1 LOC108633554 LOC108633554 RB1 RB1 TDRD7 TDRD7 HOXA5 HOXA5 LGI4 LGI4 LOC102182848 LOC102182848 KDR KDR FZD5 FZD5 LOC108636012 LOC108636012 PTH1R PTH1R BHLHA15 BHLHA15 SCARF1 SCARF1 C3 C3 KLF2 KLF2 ELSPBP1 ELSPBP1 CABYR CABYR CATSPER3 CATSPER3 ENSCHIP00000006565 ENSCHIP00000006565 LOC108633916 LOC108633916 LOC102187271 LOC102187271 MTHFSD MTHFSD ENSCHIP00000007594 ENSCHIP00000007594 PLA2G10 PLA2G10 KCNE1 KCNE1 PLD6 PLD6 ENSCHIP00000008487 ENSCHIP00000008487 EDN1 EDN1 TGFB1 TGFB1 IQCF1 IQCF1 WASHC5 WASHC5 TDRD6 TDRD6 TDRD1 TDRD1 NR4A2 NR4A2 ASCL1 ASCL1 CATSPER4 CATSPER4 C1QL1 C1QL1 MYOC MYOC TFCP2L1 TFCP2L1 ADGRB3 ADGRB3 SLC26A8 SLC26A8 ROPN1 ROPN1 G6PD G6PD SPTBN4 SPTBN4 FEV FEV CDC25B CDC25B HIF1A HIF1A REN REN ENSCHIP00000015111 ENSCHIP00000015111 RUNX2 RUNX2 ENSCHIP00000015572 ENSCHIP00000015572 BCL2 BCL2 PRKACA PRKACA IHH IHH GHRHR GHRHR EPAS1 EPAS1 SOX8 SOX8 ACTL6A ACTL6A B4GALT5 B4GALT5 CATSPER2 CATSPER2 ACTL6B ACTL6B CNTN2 CNTN2 ANGPTL8 ANGPTL8 HES1 HES1 PCSK4 PCSK4 CFTR CFTR FOXO3 FOXO3 CCL19 CCL19 LOC108638072 LOC108638072 SRRM4 SRRM4 EDNRA EDNRA SOX10 SOX10 REC8 REC8 BFSP2 BFSP2 AXL AXL CBFB CBFB GPAT4 GPAT4 BTK BTK BRCA2 BRCA2 RET RET LOC100861169 LOC100861169 ENSCHIP00000024414 ENSCHIP00000024414 LOC102189503 LOC102189503 HES5 HES5 BAP1 BAP1 TRIP13 TRIP13 TDRD10 TDRD10 BSPH1 BSPH1 ABHD2 ABHD2 ZBTB7A ZBTB7A VSX1 VSX1 L3MBTL3 L3MBTL3 YTHDF2 YTHDF2 ERCC2 ERCC2 MECP2 MECP2 IL21 IL21 LOC102190909 LOC102190909 EPB42 EPB42 EPHA8 EPHA8 FEM1B FEM1B FOXA1 FOXA1 TAL1 TAL1 KCNIP2 KCNIP2 IQCF5 IQCF5 DLD DLD TMEM79 TMEM79 TUSC2 TUSC2 IL15 IL15 PLA2G3 PLA2G3 ROPN1L ROPN1L SLC26A6 SLC26A6 C1QA C1QA TDRD15 TDRD15 GATA3 GATA3 DMC1 DMC1 KCNMA1 KCNMA1 TDRKH TDRKH CCR6 CCR6 PLP1 PLP1 SOX18 SOX18 POU2F2 POU2F2 CTNNB1 CTNNB1 EPO EPO PDE3A PDE3A BFSP1 BFSP1 GLDN GLDN MAEA MAEA ENSCHIP00000031746 ENSCHIP00000031746 RND1 RND1 GBA GBA APP APP FBXO5 FBXO5 HOXB13 HOXB13 SPINK1 SPINK1 NRCAM NRCAM TDRD5 TDRD5 SCLT1 SCLT1 SLC26A3 SLC26A3 FARP2 FARP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102171353Histone H3; Belongs to the histone H3 family. (136 aa)
SCARF2Scavenger receptor class F member 2. (879 aa)
PGRMC1Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family. (194 aa)
B4GALT6Beta-1,4-galactosyltransferase 6. (387 aa)
GDF11Growth differentiation factor 11. (406 aa)
LOC102191748Histone domain-containing protein. (136 aa)
LOC100861170Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. (64 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
LOC108633554Histone domain-containing protein. (136 aa)
RB1RB transcriptional corepressor 1. (931 aa)
TDRD7Tudor domain containing 7. (1098 aa)
HOXA5Homeobox A5. (270 aa)
LGI4Leucine rich repeat LGI family member 4. (538 aa)
LOC102182848Histone H3; Belongs to the histone H3 family. (136 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1390 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
LOC108636012Histone H3; Belongs to the histone H3 family. (136 aa)
PTH1RParathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (589 aa)
BHLHA15Basic helix-loop-helix family member a15. (186 aa)
SCARF1Scavenger receptor class F member 1. (830 aa)
C3Complement C3. (1663 aa)
KLF2Kruppel like factor 2. (361 aa)
ELSPBP1Epididymal sperm binding protein 1. (225 aa)
CABYRRIIa domain-containing protein. (382 aa)
CATSPER3Cation channel sperm associated 3. (400 aa)
ENSCHIP00000006565Uncharacterized protein. (52 aa)
LOC108633916Histone H3; Belongs to the histone H3 family. (136 aa)
LOC102187271Rhodanese domain-containing protein. (506 aa)
MTHFSDMethenyltetrahydrofolate synthetase domain containing. (380 aa)
ENSCHIP00000007594Ubiquitin carboxyl-terminal hydrolase. (721 aa)
PLA2G10Phospholipase A(2). (158 aa)
KCNE1Uncharacterized protein. (129 aa)
PLD6Phospholipase D family member 6. (220 aa)
ENSCHIP00000008487Uncharacterized protein. (123 aa)
EDN1Endothelin 1. (202 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
IQCF1IQ motif containing F1. (203 aa)
WASHC5WASH complex subunit 5. (1159 aa)
TDRD6Tudor domain containing 6. (2099 aa)
TDRD1Tudor domain containing 1. (1185 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (609 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (219 aa)
CATSPER4Cation channel sperm associated 4. (446 aa)
C1QL1Complement C1q like 1. (258 aa)
MYOCMyocilin. (490 aa)
TFCP2L1Transcription factor CP2 like 1. (489 aa)
ADGRB3Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family. (1282 aa)
SLC26A8Testis anion transporter 1. (912 aa)
ROPN1Uncharacterized protein. (212 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (515 aa)
SPTBN4Spectrin beta chain; Belongs to the spectrin family. (2564 aa)
FEVFEV transcription factor, ETS family member. (237 aa)
CDC25BRhodanese domain-containing protein. (564 aa)
HIF1AUncharacterized protein. (823 aa)
RENRenin; Belongs to the peptidase A1 family. (403 aa)
ENSCHIP00000015111Uncharacterized protein. (97 aa)
RUNX2RUNX family transcription factor 2. (585 aa)
ENSCHIP00000015572Fibronectin type-II domain-containing protein. (154 aa)
BCL2BH4_2 domain-containing protein. (229 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (360 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (498 aa)
EPAS1Endothelial PAS domain protein 1. (898 aa)
SOX8SRY-box transcription factor 8. (534 aa)
ACTL6AActin like 6A; Belongs to the actin family. (458 aa)
B4GALT5Beta-1,4-galactosyltransferase 5. (388 aa)
CATSPER2Cation channel sperm associated 2. (556 aa)
ACTL6BActin like 6B; Belongs to the actin family. (431 aa)
CNTN2Contactin 2. (1046 aa)
ANGPTL8Angiopoietin like 8. (199 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (804 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1524 aa)
FOXO3Forkhead box O3. (672 aa)
CCL19C-C motif chemokine. (102 aa)
LOC108638072Uncharacterized protein. (152 aa)
SRRM4Serine/arginine repetitive matrix 4. (557 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
SOX10SRY-box transcription factor 10. (469 aa)
REC8REC8 meiotic recombination protein. (564 aa)
BFSP2Beaded filament structural protein 2; Belongs to the intermediate filament family. (422 aa)
AXLAXL receptor tyrosine kinase. (887 aa)
CBFBCore-binding factor subunit beta. (187 aa)
GPAT4Glycerol-3-phosphate acyltransferase 4. (456 aa)
BTKTyrosine-protein kinase. (658 aa)
BRCA2BRCA2 DNA repair associated. (3405 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1118 aa)
LOC100861169Uncharacterized protein. (73 aa)
ENSCHIP00000024414Uncharacterized protein. (57 aa)
LOC102189503Histone H3; Belongs to the histone H3 family. (136 aa)
HES5Hes family bHLH transcription factor 5. (165 aa)
BAP1Ubiquitin carboxyl-terminal hydrolase. (729 aa)
TRIP13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (432 aa)
TDRD10Tudor domain containing 10. (382 aa)
BSPH1Binder of sperm protein homolog 1. (111 aa)
ABHD2Abhydrolase domain containing 2. (425 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (602 aa)
VSX1Visual system homeobox 1. (365 aa)
L3MBTL3L3MBTL histone methyl-lysine binding protein 3. (840 aa)
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (582 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (481 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (157 aa)
LOC102190909Histone H3.3. (136 aa)
EPB42Erythrocyte membrane protein band 4.2. (687 aa)
EPHA8EPH receptor A8. (1005 aa)
FEM1BFem-1 homolog B. (627 aa)
FOXA1Forkhead box A1. (468 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (328 aa)
KCNIP2Potassium voltage-gated channel interacting protein 2. (270 aa)
IQCF5IQ motif containing F5. (182 aa)
DLDDihydrolipoyl dehydrogenase. (509 aa)
TMEM79Transmembrane protein 79. (395 aa)
TUSC2Uncharacterized protein. (110 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (161 aa)
PLA2G3Phospholipase A2 group III. (509 aa)
ROPN1LRhophilin associated tail protein 1 like. (228 aa)
SLC26A6Solute carrier family 26 member 6. (760 aa)
C1QAComplement C1q A chain. (313 aa)
TDRD15Tudor domain containing 15. (2085 aa)
GATA3GATA binding protein 3. (467 aa)
DMC1Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (340 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1131 aa)
TDRKHTudor and KH domain containing. (575 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (375 aa)
PLP1Proteolipid protein 1. (277 aa)
SOX18SRY-box transcription factor 18. (393 aa)
POU2F2POU domain protein. (479 aa)
CTNNB1Catenin beta 1. (781 aa)
EPOErythropoietin. (208 aa)
PDE3APhosphodiesterase. (834 aa)
BFSP1Beaded filament structural protein 1; Belongs to the intermediate filament family. (737 aa)
GLDNGliomedin. (551 aa)
MAEAMacrophage erythroblast attacher. (434 aa)
ENSCHIP00000031746Uncharacterized protein. (198 aa)
RND1Rho family GTPase 1. (232 aa)
GBAGlucosylceramidase. (536 aa)
APPAmyloid beta precursor protein. (770 aa)
FBXO5F-box protein 5. (448 aa)
HOXB13Homeobox B13. (285 aa)
SPINK1Serine peptidase inhibitor, Kazal type 1. (79 aa)
NRCAMNeuronal cell adhesion molecule. (1304 aa)
TDRD5Tudor domain containing 5. (1034 aa)
SCLT1Sodium channel and clathrin linker 1. (576 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (760 aa)
FARP2FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1042 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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