STRINGSTRING
TFAP2B TFAP2B NF1 NF1 HAND2 HAND2 ENSCHIP00000010266 ENSCHIP00000010266 ASCL1 ASCL1 SOX4 SOX4 NRP2 NRP2 PHOX2B PHOX2B PHOX2A PHOX2A EDNRA EDNRA SEMA3F SEMA3F GDNF GDNF NTRK1 NTRK1 FZD3 FZD3 TP63 TP63 GATA3 GATA3 CTNNB1 CTNNB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TFAP2BTranscription factor AP-2 beta. (476 aa)
NF1Neurofibromin 1. (2848 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
ENSCHIP00000010266Plexin_cytopl domain-containing protein. (255 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (219 aa)
SOX4SRY-box transcription factor 4. (504 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (926 aa)
PHOX2BPaired like homeobox 2B. (315 aa)
PHOX2APaired like homeobox 2A. (284 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (764 aa)
GDNFGlial cell derived neurotrophic factor. (211 aa)
NTRK1Tyrosine-protein kinase receptor. (821 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (681 aa)
GATA3GATA binding protein 3. (467 aa)
CTNNB1Catenin beta 1. (781 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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