STRINGSTRING
SHOX2 SHOX2 TCF21 TCF21 GLI3 GLI3 HLX HLX FGF10 FGF10 NIPBL NIPBL SIX2 SIX2 ENSCHIP00000005279 ENSCHIP00000005279 ENSCHIP00000003193 ENSCHIP00000003193 PDGFRA PDGFRA ID2 ID2 FOXF1 FOXF1 SHH SHH RBPMS2 RBPMS2 IHH IHH HNF1B HNF1B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SHOX2Short stature homeobox 2. (319 aa)
TCF21Transcription factor 21. (179 aa)
GLI3GLI family zinc finger 3. (1614 aa)
HLXH2.0 like homeobox. (488 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
NIPBLNipped-B protein. (2804 aa)
SIX2SIX homeobox 2. (296 aa)
ENSCHIP00000005279RRM domain-containing protein. (80 aa)
ENSCHIP00000003193BHLH domain-containing protein. (122 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1108 aa)
ID2BHLH domain-containing protein. (134 aa)
FOXF1Forkhead box F1. (391 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
RBPMS2RNA binding protein, mRNA processing factor 2. (197 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
HNF1BHNF1 homeobox B. (558 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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