(16 nodes) Regulation of muscle organ development network (Capra hircus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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co-expression

protein homology

Your Input:
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	FGF3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (232 aa)
	GJA1	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
	TIFAB	TIFA inhibitor. (197 aa)
	SFMBT1	Scm like with four mbt domains 1. (865 aa)
	NEUROG1	Neurogenin 1. (246 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	ERBB3	Erb-b2 receptor tyrosine kinase 3. (1344 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
	MRTFB	Myocardin related transcription factor B. (1113 aa)
	SIRT2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (390 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	SOX15	SRY-box transcription factor 15. (233 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
	LEF1	HMG box domain-containing protein. (430 aa)
	CREB1	cAMP responsive element binding protein 1. (341 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	FGF3	ENSCHIP00000023678	ENSCHIP00000001019	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.634
BMP4	FGF8	ENSCHIP00000023678	ENSCHIP00000016903	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.763
BMP4	GJA1	ENSCHIP00000023678	ENSCHIP00000001879	Bone morphogenetic protein 4.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.525
BMP4	LEF1	ENSCHIP00000023678	ENSCHIP00000030629	Bone morphogenetic protein 4.	HMG box domain-containing protein.	0.714
BMP4	SHH	ENSCHIP00000023678	ENSCHIP00000027767	Bone morphogenetic protein 4.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.909
BMP4	SMAD3	ENSCHIP00000023678	ENSCHIP00000011729	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.808
BMP4	TGFB1	ENSCHIP00000023678	ENSCHIP00000008885	Bone morphogenetic protein 4.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.495
CREB1	LEF1	ENSCHIP00000033719	ENSCHIP00000030629	cAMP responsive element binding protein 1.	HMG box domain-containing protein.	0.440
CREB1	SMAD3	ENSCHIP00000033719	ENSCHIP00000011729	cAMP responsive element binding protein 1.	Mothers against decapentaplegic homolog.	0.478
CREB1	TGFB1	ENSCHIP00000033719	ENSCHIP00000008885	cAMP responsive element binding protein 1.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.453
ERBB3	FGF3	ENSCHIP00000012135	ENSCHIP00000001019	Erb-b2 receptor tyrosine kinase 3.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.684
ERBB3	FGF8	ENSCHIP00000012135	ENSCHIP00000016903	Erb-b2 receptor tyrosine kinase 3.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.687
FGF3	BMP4	ENSCHIP00000001019	ENSCHIP00000023678	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 4.	0.634
FGF3	ERBB3	ENSCHIP00000001019	ENSCHIP00000012135	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Erb-b2 receptor tyrosine kinase 3.	0.684
FGF3	FGF8	ENSCHIP00000001019	ENSCHIP00000016903	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.754
FGF3	NEUROG1	ENSCHIP00000001019	ENSCHIP00000011136	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Neurogenin 1.	0.442
FGF3	SHH	ENSCHIP00000001019	ENSCHIP00000027767	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.662
FGF3	TGFB1	ENSCHIP00000001019	ENSCHIP00000008885	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.515
FGF8	BMP4	ENSCHIP00000016903	ENSCHIP00000023678	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 4.	0.763
FGF8	ERBB3	ENSCHIP00000016903	ENSCHIP00000012135	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Erb-b2 receptor tyrosine kinase 3.	0.687