STRINGSTRING
SEMA3B SEMA3B SEMA4A SEMA4A SEMA3G SEMA3G MSTN MSTN LOC102175492 LOC102175492 FSTL4 FSTL4 RYK RYK TBX5 TBX5 EPHA7 EPHA7 BBS2 BBS2 NTN1 NTN1 OSTN OSTN BMP4 BMP4 SEMA5B SEMA5B SEMA4B SEMA4B RAI1 RAI1 DUSP10 DUSP10 SEMA3E SEMA3E KIAA0319 KIAA0319 MT3 MT3 FXN FXN ULK1 ULK1 WNT3 WNT3 MAPK11 MAPK11 SEMA3D SEMA3D SEMA6A SEMA6A SEMA4G SEMA4G SEMA4C SEMA4C SEMA3C SEMA3C SEMA4F SEMA4F WWC2 WWC2 WNT3A WNT3A WNT5A WNT5A CDKN1B CDKN1B SEMA3A SEMA3A PTCH1 PTCH1 ADRB3 ADRB3 SEMA5A SEMA5A WWC1 WWC1 SAV1 SAV1 SEMA6D SEMA6D PI16 PI16 TP73 TP73 STK3 STK3 DIP2B DIP2B NOG NOG TNR TNR CDKL3 CDKL3 ADRB1 ADRB1 TLL2 TLL2 JARID2 JARID2 RTN4 RTN4 CDKN1A CDKN1A LOC108633189 LOC108633189 SLC6A4 SLC6A4 STK4 STK4 SEMA3F SEMA3F NKD1 NKD1 PLXNA3 PLXNA3 PLAC8 PLAC8 DRAXIN DRAXIN ENSCHIP00000001557 ENSCHIP00000001557 SEMA4D SEMA4D WWC3 WWC3 MYOZ1 MYOZ1 LGMN LGMN SPART SPART SEMA7A SEMA7A SEMA6B SEMA6B RTN4R RTN4R CDK5 CDK5 ENSCHIP00000032619 ENSCHIP00000032619 IFRD2 IFRD2 SOCS2 SOCS2 PTPRS PTPRS GDF15 GDF15 SEMA6C SEMA6C GSK3A GSK3A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (773 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (762 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (769 aa)
MSTNGrowth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family. (375 aa)
LOC102175492ANK_REP_REGION domain-containing protein. (1589 aa)
FSTL4Follistatin like 4. (843 aa)
RYKReceptor like tyrosine kinase. (609 aa)
TBX5T-box transcription factor 5. (594 aa)
EPHA7EPH receptor A7. (998 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (730 aa)
NTN1Netrin 1. (496 aa)
OSTNOsteocrin. (132 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
SEMA5BSemaphorin 5B. (1043 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (826 aa)
RAI1Retinoic acid induced 1. (1904 aa)
DUSP10Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (775 aa)
KIAA0319KIAA0319. (1066 aa)
MT3Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (68 aa)
FXNFrataxin. (217 aa)
ULK1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1055 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
MAPK11Mitogen-activated protein kinase. (417 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (775 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1046 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (844 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (833 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (765 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (764 aa)
WWC2WW and C2 domain containing 2. (1204 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (772 aa)
PTCH1Patched 1. (1453 aa)
ADRB3Beta-3 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta- 3 is involved in the regulation of lipolysis and thermogenesis. (430 aa)
SEMA5ASemaphorin 5A. (1073 aa)
WWC1WW and C2 domain containing 1. (1094 aa)
SAV1Salvador family WW domain containing protein 1. (384 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1073 aa)
PI16Peptidase inhibitor 16; Belongs to the CRISP family. (464 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (640 aa)
STK3Serine/threonine kinase 3. (495 aa)
DIP2BDisco interacting protein 2 homolog B. (1554 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
TNRTenascin R. (1358 aa)
CDKL3Cyclin dependent kinase like 3. (717 aa)
ADRB1Adrenoceptor beta 1. (467 aa)
TLL2Metalloendopeptidase. (1020 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (1258 aa)
RTN4Reticulon. (1194 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (161 aa)
LOC108633189Uncharacterized protein. (241 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
STK4Serine/threonine kinase 4. (487 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (764 aa)
NKD1NKD inhibitor of WNT signaling pathway 1. (471 aa)
PLXNA3Plexin A3. (1822 aa)
PLAC8Placenta associated 8. (116 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (346 aa)
ENSCHIP00000001557Ig-like domain-containing protein. (122 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (863 aa)
WWC3WWC family member 3. (1236 aa)
MYOZ1Myozenin 1. (302 aa)
LGMNLegumain. (433 aa)
SPARTSpartin. (668 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (664 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (920 aa)
RTN4RReticulon 4 receptor. (473 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
ENSCHIP00000032619ANK_REP_REGION domain-containing protein. (266 aa)
IFRD2Interferon related developmental regulator 2. (442 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1926 aa)
GDF15Growth differentiation factor 15. (308 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (964 aa)
GSK3AProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (483 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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