STRINGSTRING
FEZF2 FEZF2 ZNF521 ZNF521 NKX6-2 NKX6-2 POU4F1 POU4F1 HOXC10 HOXC10 ENSCHIP00000003193 ENSCHIP00000003193 OLIG2 OLIG2 POU3F2 POU3F2 EPOP EPOP TLX3 TLX3 PRRX1 PRRX1 OLIG3 OLIG3 ATOH1 ATOH1 HOXD10 HOXD10 TBR1 TBR1 DMRT3 DMRT3 ASCL1 ASCL1 EHMT2 EHMT2 CDC42 CDC42 MNX1 MNX1 DLX1 DLX1 DMRTA2 DMRTA2 GLI3 GLI3 FEV FEV DLL4 DLL4 ISL2 ISL2 JAG2 JAG2 MYT1L MYT1L IHH IHH GSX2 GSX2 ID2 ID2 WNT1 WNT1 SMAD4 SMAD4 BCL11B BCL11B OLIG1 OLIG1 GBX1 GBX1 DLL1 DLL1 BMP4 BMP4 NOTCH1 NOTCH1 PROX1 PROX1 SOX9 SOX9 SUFU SUFU EYA1 EYA1 DLX6 DLX6 TGFBR1 TGFBR1 ISL1 ISL1 FOXG1 FOXG1 DBX1 DBX1 PAX6 PAX6 FOXA1 FOXA1 SHH SHH LBX1 LBX1 NKX2-1 NKX2-1 PTF1A PTF1A FOXN4 FOXN4 LHX3 LHX3 DLX2 DLX2 SIX1 SIX1 NKX2-2 NKX2-2 CTNNB1 CTNNB1 GSX1 GSX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FEZF2FEZ family zinc finger 2. (459 aa)
ZNF521Zinc finger protein 521. (1311 aa)
NKX6-2NK6 homeobox 2. (286 aa)
POU4F1POU domain protein. (421 aa)
HOXC10Homeobox C10. (342 aa)
ENSCHIP00000003193BHLH domain-containing protein. (122 aa)
OLIG2Oligodendrocyte transcription factor 2. (329 aa)
POU3F2POU domain protein. (438 aa)
EPOPElongin BC and polycomb repressive complex 2 associated protein. (379 aa)
TLX3T cell leukemia homeobox 3. (291 aa)
PRRX1Paired related homeobox 1. (245 aa)
OLIG3Oligodendrocyte transcription factor 3. (272 aa)
ATOH1Atonal bHLH transcription factor 1. (352 aa)
HOXD10Homeobox D10. (340 aa)
TBR1T-box brain transcription factor 1. (682 aa)
DMRT3Doublesex and mab-3 related transcription factor 3. (472 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (219 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1268 aa)
CDC42Uncharacterized protein. (191 aa)
MNX1Motor neuron and pancreas homeobox 1. (411 aa)
DLX1Distal-less homeobox 1. (255 aa)
DMRTA2DMRT like family A2. (535 aa)
GLI3GLI family zinc finger 3. (1614 aa)
FEVFEV transcription factor, ETS family member. (237 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (701 aa)
ISL2ISL LIM homeobox 2. (359 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1069 aa)
MYT1LMyelin transcription factor 1 like. (1177 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
GSX2GS homeobox 2. (305 aa)
ID2BHLH domain-containing protein. (134 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
SMAD4Mothers against decapentaplegic homolog. (513 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (905 aa)
OLIG1Oligodendrocyte transcription factor 1. (259 aa)
GBX1Gastrulation brain homeobox 1. (413 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
NOTCH1Notch receptor 1. (2508 aa)
PROX1Prospero homeobox 1. (734 aa)
SOX9SRY-box transcription factor 9. (525 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (485 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (618 aa)
DLX6Distal-less homeobox 6. (230 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
ISL1ISL LIM homeobox 1. (349 aa)
FOXG1Forkhead box G1. (538 aa)
DBX1Developing brain homeobox 1. (345 aa)
PAX6Paired box 6. (486 aa)
FOXA1Forkhead box A1. (468 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
LBX1Ladybird homeobox 1. (281 aa)
NKX2-1NK2 homeobox 1. (370 aa)
PTF1APancreas associated transcription factor 1a. (325 aa)
FOXN4Forkhead box N4. (518 aa)
LHX3LIM homeobox 3. (403 aa)
DLX2Distal-less homeobox 2. (328 aa)
SIX1SIX homeobox 1. (284 aa)
NKX2-2NK2 homeobox 2. (273 aa)
CTNNB1Catenin beta 1. (781 aa)
GSX1GS homeobox 1. (266 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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