STRINGSTRING
SLC39A3 SLC39A3 OSR2 OSR2 HOXD4 HOXD4 ZEB1 ZEB1 WNT5A WNT5A SHOX2 SHOX2 RUNX2 RUNX2 HOXC9 HOXC9 HOXA6 HOXA6 CHST11 CHST11 HOXB8 HOXB8 GLI3 GLI3 MEGF8 MEGF8 MYF5 MYF5 SULF2 SULF2 IHH IHH TBX15 TBX15 DLX1 DLX1 HOXA3 HOXA3 HOXB3 HOXB3 SMAD3 SMAD3 WDR19 WDR19 TAPT1 TAPT1 MMP16 MMP16 HOXC6 HOXC6 HAND2 HAND2 SIX4 SIX4 IRX5 IRX5 SLC39A1 SLC39A1 HOXD10 HOXD10 HOXD3 HOXD3 TGFBR2 TGFBR2 NIPBL NIPBL TBXT TBXT NKX3-2 NKX3-2 MMP14 MMP14 SIX2 SIX2 ALX4 ALX4 PRRX1 PRRX1 DLG1 DLG1 BMP7 BMP7 ENSCHIP00000005724 ENSCHIP00000005724 COL2A1 COL2A1 NOG NOG EXT1 EXT1 HOXB6 HOXB6 HOXA5 HOXA5 PDGFRA PDGFRA PCSK5 PCSK5 HOXA9 HOXA9 SLC2A10 SLC2A10 NODAL NODAL ENSCHIP00000000097 ENSCHIP00000000097 HOXA4 HOXA4 EDNRA EDNRA DMRT2 DMRT2 OSR1 OSR1 SMAD2 SMAD2 MDFI MDFI LOC108634984 LOC108634984 HOXA11 HOXA11 FGF9 FGF9 BMP4 BMP4 COL1A1 COL1A1 FUZ FUZ WNT11 WNT11 HOXA7 HOXA7 EYA1 EYA1 LHX1 LHX1 GSC GSC SATB2 SATB2 TGFBR1 TGFBR1 KIAA1217 KIAA1217 HOXB9 HOXB9 DSCAML1 DSCAML1 HOXB5 HOXB5 HOXD9 HOXD9 HYAL1 HYAL1 SHH SHH MKS1 MKS1 EIF4A3 EIF4A3 SP3 SP3 HOXA2 HOXA2 FLVCR1 FLVCR1 DLG2 DLG2 DLX2 DLX2 SIX1 SIX1 HOXC11 HOXC11 HOXB4 HOXB4 ALX1 ALX1 UCMA UCMA CTNNB1 CTNNB1 HOXB2 HOXB2 HOXC4 HOXC4 ALX3 ALX3 MTHFD1L MTHFD1L TULP3 TULP3 SULF1 SULF1 MED12 MED12 RDH10 RDH10 WNT9B WNT9B BMI1 BMI1 FGF8 FGF8 IFT140 IFT140 NDST1 NDST1 HOXD1 HOXD1 HOXB7 HOXB7 GRHL2 GRHL2 HOXB1 HOXB1 FGFR2 FGFR2 PAX5 PAX5 WDR60 WDR60 TFAP2A TFAP2A SETD2 SETD2 PCGF2 PCGF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC39A3Uncharacterized protein. (283 aa)
OSR2Odd-skipped related transciption factor 2. (276 aa)
HOXD4Homeobox D4. (258 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1127 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
SHOX2Short stature homeobox 2. (319 aa)
RUNX2RUNX family transcription factor 2. (585 aa)
HOXC9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (260 aa)
HOXA6Homeobox A6. (233 aa)
CHST11Carbohydrate sulfotransferase. (362 aa)
HOXB8Homeobox B8. (243 aa)
GLI3GLI family zinc finger 3. (1614 aa)
MEGF8Multiple EGF like domains 8. (2836 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (260 aa)
SULF2Sulfatase 2. (864 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
TBX15T-box transcription factor 15. (602 aa)
DLX1Distal-less homeobox 1. (255 aa)
HOXA3Homeobox A3. (437 aa)
HOXB3Homeobox B3. (426 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
WDR19WD repeat domain 19. (1335 aa)
TAPT1Transmembrane anterior posterior transformation 1. (564 aa)
MMP16Matrix metallopeptidase 16. (607 aa)
HOXC6Homeobox C6. (235 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
SIX4SIX homeobox 4. (784 aa)
IRX5Iroquois homeobox 5. (483 aa)
SLC39A1Uncharacterized protein. (324 aa)
HOXD10Homeobox D10. (340 aa)
HOXD3Homeobox D3. (433 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (550 aa)
NIPBLNipped-B protein. (2804 aa)
TBXTT-box transcription factor T. (435 aa)
NKX3-2NK3 homeobox 2. (330 aa)
MMP14ZnMc domain-containing protein. (584 aa)
SIX2SIX homeobox 2. (296 aa)
ALX4ALX homeobox 4. (397 aa)
PRRX1Paired related homeobox 1. (245 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (927 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
ENSCHIP00000005724Uncharacterized protein. (62 aa)
COL2A1Collagen type II alpha 1 chain. (1259 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (446 aa)
HOXB6Homeobox B6. (224 aa)
HOXA5Homeobox A5. (270 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1108 aa)
PCSK5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1884 aa)
HOXA9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (279 aa)
SLC2A10Solute carrier family 2 member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (536 aa)
NODALNodal growth differentiation factor. (346 aa)
ENSCHIP00000000097Med12-PQL domain-containing protein. (315 aa)
HOXA4Homeobox A4. (298 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
DMRT2Doublesex and mab-3 related transcription factor 2. (558 aa)
OSR1Odd-skipped related transcription factor 1. (267 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
MDFIMyoD family inhibitor. (247 aa)
LOC108634984Uncharacterized protein. (140 aa)
HOXA11Homeobox A11. (317 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
COL1A1Collagen type I alpha 1 chain. (1463 aa)
FUZFuzzy planar cell polarity protein. (419 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
HOXA7Homeobox A7. (239 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (618 aa)
LHX1LIM homeobox 1. (406 aa)
GSCGoosecoid homeobox. (257 aa)
SATB2DNA-binding protein SATB. (733 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
KIAA1217KIAA1217. (1971 aa)
HOXB9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (250 aa)
DSCAML1DS cell adhesion molecule like 1. (1811 aa)
HOXB5Homeobox B5. (269 aa)
HOXD9Homeobox D9. (351 aa)
HYAL1Hyaluronidase. (450 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
MKS1MKS transition zone complex subunit 1. (645 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (411 aa)
SP3Sp3 transcription factor. (778 aa)
HOXA2Homeobox A2. (372 aa)
FLVCR1Feline leukemia virus subgroup C cellular receptor 1. (556 aa)
DLG2Discs large MAGUK scaffold protein 2. (901 aa)
DLX2Distal-less homeobox 2. (328 aa)
SIX1SIX homeobox 1. (284 aa)
HOXC11Homeobox C11. (304 aa)
HOXB4Homeobox B4. (251 aa)
ALX1ALX homeobox 1. (326 aa)
UCMAUpper zone of growth plate and cartilage matrix associated. (132 aa)
CTNNB1Catenin beta 1. (781 aa)
HOXB2Homeobox B2. (354 aa)
HOXC4Homeobox C4. (264 aa)
ALX3ALX homeobox 3. (343 aa)
MTHFD1LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (975 aa)
TULP3Tubby-like protein; Belongs to the TUB family. (488 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (868 aa)
MED12Med12 domain-containing protein. (2040 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
BMI1RING-type domain-containing protein. (437 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
IFT140Intraflagellar transport 140. (1457 aa)
NDST1N-deacetylase and N-sulfotransferase 1. (882 aa)
HOXD1Homeobox D1. (322 aa)
HOXB7Homeobox B7. (217 aa)
GRHL2Grainyhead like transcription factor 2. (622 aa)
HOXB1Homeobox B1. (302 aa)
FGFR2Fibroblast growth factor receptor. (841 aa)
PAX5Paired box 5. (392 aa)
WDR60Uncharacterized protein. (1068 aa)
TFAP2ATranscription factor AP-2 alpha. (485 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2556 aa)
PCGF2Polycomb group ring finger 2. (344 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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