STRINGSTRING
CYS1 CYS1 ATG4B ATG4B MPV17 MPV17 CELSR1 CELSR1 OTX1 OTX1 INSIG2 INSIG2 HES1 HES1 PHOX2B PHOX2B C1QB C1QB CHRNA9 CHRNA9 FZD6 FZD6 ENSCHIP00000017192 ENSCHIP00000017192 GBX2 GBX2 FGF8 FGF8 LOC102173415 LOC102173415 BLOC1S5 BLOC1S5 RPGRIP1L RPGRIP1L ZEB1 ZEB1 TTC8 TTC8 WNT3A WNT3A WNT5A WNT5A CDKN1B CDKN1B FAT4 FAT4 JAG2 JAG2 SLC4A7 SLC4A7 FOXI1 FOXI1 HPCA HPCA ANP32B ANP32B GLI3 GLI3 FGF20 FGF20 DVL1 DVL1 C1QTNF5 C1QTNF5 KCNQ4 KCNQ4 SOD1 SOD1 CECR2 CECR2 STOX1 STOX1 CYTL1 CYTL1 GRXCR2 GRXCR2 TSKU TSKU LIN7A LIN7A PDZD7 PDZD7 TCAP TCAP LRP10 LRP10 USH1C USH1C FGFR3 FGFR3 ADAM10 ADAM10 RIPOR2 RIPOR2 PLS1 PLS1 SOBP SOBP TIFAB TIFAB HOXA13 HOXA13 SPRY2 SPRY2 CXCL14 CXCL14 DLX5 DLX5 TTC39C TTC39C COL2A1 COL2A1 PLPPR4 PLPPR4 PRRX1 PRRX1 CLRN1 CLRN1 USH1G USH1G SLC9A3R1 SLC9A3R1 HMX3 HMX3 ATOH1 ATOH1 LHFPL5 LHFPL5 IFT20 IFT20 CHD7 CHD7 SIX4 SIX4 TBX3 TBX3 ATP8B1 ATP8B1 FGF10 FGF10 LRIG1 LRIG1 CTHRC1 CTHRC1 DUOX2 DUOX2 BMP2 BMP2 PJVK PJVK DCHS1 DCHS1 ENSCHIP00000010686 ENSCHIP00000010686 MAFB MAFB CDH23 CDH23 NEUROG1 NEUROG1 NEUROD1 NEUROD1 NOX3 NOX3 ENSCHIP00000012540 ENSCHIP00000012540 ATP6V1B1 ATP6V1B1 TBX2 TBX2 FZD3 FZD3 INSIG1 INSIG1 SLC44A4 SLC44A4 EPHB2 EPHB2 MAF MAF FOXG1 FOXG1 GRXCR1 GRXCR1 FREM2 FREM2 STRC STRC EYA1 EYA1 HES5 HES5 SOX9 SOX9 CLRN2 CLRN2 PROX1 PROX1 FRZB FRZB NOTCH1 NOTCH1 BMP4 BMP4 NTN1 NTN1 USH2A USH2A SHH SHH MKS1 MKS1 HESX1 HESX1 GABRA5 GABRA5 HPN HPN LRIG3 LRIG3 TRIP11 TRIP11 PAFAH1B1 PAFAH1B1 TPRN TPRN LHX3 LHX3 GABRB2 GABRB2 WHRN WHRN SIX1 SIX1 EPHA4 EPHA4 GATA3 GATA3 KCNMA1 KCNMA1 AHI1 AHI1 NAGLU NAGLU DVL2 DVL2 HMX2 HMX2 OCM2 OCM2 PTPRQ PTPRQ GSDME GSDME HEY2 HEY2 MAPKAPK2 MAPKAPK2 ROR1 ROR1 LRRC1 LRRC1 IFT88 IFT88 KCNQ1 KCNQ1 DLL1 DLL1 ALDH1A3 ALDH1A3 FGF9 FGF9 CCM2 CCM2 ENSCHIP00000021920 ENSCHIP00000021920 BCR BCR PAX8 PAX8 MCM2 MCM2 PTK7 PTK7 JAG1 JAG1 TMIE TMIE ATG5 ATG5 PCDH15 PCDH15 OTOP1 OTOP1 PTPN11 PTPN11 SCRIB SCRIB WNT1 WNT1 WDPCP WDPCP GRHL3 GRHL3 MCOLN3 MCOLN3 POU4F3 POU4F3 TSHR TSHR MYO6 MYO6 BMPER BMPER SEC24B SEC24B TFAP2A TFAP2A FGF2 FGF2 LGR5 LGR5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CYS1Cystin 1. (156 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (376 aa)
MPV17Mitochondrial inner membrane protein MPV17; Belongs to the peroxisomal membrane protein PXMP2/4 family. (170 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2710 aa)
OTX1Orthodenticle homeobox 1. (355 aa)
INSIG2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (245 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
PHOX2BPaired like homeobox 2B. (315 aa)
C1QBComplement C1q B chain. (247 aa)
CHRNA9Cholinergic receptor nicotinic alpha 9 subunit. (479 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (714 aa)
ENSCHIP00000017192Uncharacterized protein. (295 aa)
GBX2Gastrulation brain homeobox 2. (349 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
LOC102173415Uncharacterized protein. (242 aa)
BLOC1S5Biogenesis of lysosome-related organelles complex 1 subunit 5; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). (192 aa)
RPGRIP1LRPGRIP1 like. (1295 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1127 aa)
TTC8Tetratricopeptide repeat domain 8. (511 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
FAT4FAT atypical cadherin 4. (4982 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1069 aa)
SLC4A7Anion exchange protein. (1219 aa)
FOXI1Forkhead box I1. (379 aa)
HPCAHippocalcin. (193 aa)
ANP32BLRRcap domain-containing protein. (226 aa)
GLI3GLI family zinc finger 3. (1614 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
DVL1Dishevelled segment polarity protein 1. (682 aa)
C1QTNF5C1q and TNF related 5. (243 aa)
KCNQ4Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (695 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
CECR2CECR2 histone acetyl-lysine reader. (1449 aa)
STOX1Storkhead box 1. (981 aa)
CYTL1Cytokine like 1. (136 aa)
GRXCR2Glutaredoxin and cysteine rich domain containing 2. (246 aa)
TSKUTsukushi, small leucine rich proteoglycan. (359 aa)
LIN7AProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (233 aa)
PDZD7PDZ domain containing 7. (1008 aa)
TCAPUncharacterized protein. (167 aa)
LRP10LDL receptor related protein 10. (724 aa)
USH1CUSH1 protein network component harmonin. (877 aa)
FGFR3Receptor protein-tyrosine kinase. (710 aa)
ADAM10ADAM metallopeptidase domain 10. (750 aa)
RIPOR2Uncharacterized protein. (1052 aa)
PLS1Plastin 1. (630 aa)
SOBPSine oculis binding protein homolog. (873 aa)
TIFABTIFA inhibitor. (197 aa)
HOXA13Homeobox A13. (388 aa)
SPRY2Sprouty RTK signaling antagonist 2. (315 aa)
CXCL14C-X-C motif chemokine ligand 14. (99 aa)
DLX5Distal-less homeobox 5. (289 aa)
TTC39CTetratricopeptide repeat domain 39C. (578 aa)
COL2A1Collagen type II alpha 1 chain. (1259 aa)
PLPPR4Phospholipid phosphatase related 4. (751 aa)
PRRX1Paired related homeobox 1. (245 aa)
CLRN1Clarin 1. (232 aa)
USH1GUSH1 protein network component sans. (462 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (386 aa)
HMX3H6 family homeobox 3. (360 aa)
ATOH1Atonal bHLH transcription factor 1. (352 aa)
LHFPL5LHFPL tetraspan subfamily member 5. (236 aa)
IFT20Intraflagellar transport 20. (156 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2993 aa)
SIX4SIX homeobox 4. (784 aa)
TBX3T-box transcription factor 3. (749 aa)
ATP8B1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1251 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (1089 aa)
CTHRC1Collagen triple helix repeat containing 1. (243 aa)
DUOX2Dual oxidase 2. (1529 aa)
BMP2TGF_BETA_2 domain-containing protein. (381 aa)
PJVKPejvakin. (352 aa)
DCHS1Dachsous cadherin-related 1. (3258 aa)
ENSCHIP00000010686CCM2_C domain-containing protein. (440 aa)
MAFBMAF bZIP transcription factor B. (329 aa)
CDH23Cadherin related 23. (3343 aa)
NEUROG1Neurogenin 1. (246 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
NOX3NADPH oxidase 3. (579 aa)
ENSCHIP00000012540Uncharacterized protein. (404 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
TBX2T-box transcription factor 2. (771 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (278 aa)
SLC44A4Solute carrier family 44 member 4; Belongs to the CTL (choline transporter-like) family. (700 aa)
EPHB2EPH receptor B2. (1016 aa)
MAFMAF bZIP transcription factor; Belongs to the bZIP family. (404 aa)
FOXG1Forkhead box G1. (538 aa)
GRXCR1Glutaredoxin and cysteine rich domain containing 1. (290 aa)
FREM2FRAS1 related extracellular matrix 2. (3251 aa)
STRCStereocilin. (1752 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (618 aa)
HES5Hes family bHLH transcription factor 5. (165 aa)
SOX9SRY-box transcription factor 9. (525 aa)
CLRN2Clarin 2. (232 aa)
PROX1Prospero homeobox 1. (734 aa)
FRZBFrizzled related protein. (325 aa)
NOTCH1Notch receptor 1. (2508 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
NTN1Netrin 1. (496 aa)
USH2AUncharacterized protein. (1518 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
MKS1MKS transition zone complex subunit 1. (645 aa)
HESX1HESX homeobox 1. (185 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
HPNHepsin; Belongs to the peptidase S1 family. (417 aa)
LRIG3Leucine rich repeats and immunoglobulin like domains 3. (1120 aa)
TRIP11Thyroid hormone receptor interactor 11. (1975 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
TPRNTaperin. (706 aa)
LHX3LIM homeobox 3. (403 aa)
GABRB2Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
WHRNWhirlin. (918 aa)
SIX1SIX homeobox 1. (284 aa)
EPHA4EPH receptor A4. (986 aa)
GATA3GATA binding protein 3. (467 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1131 aa)
AHI1Abelson helper integration site 1. (1194 aa)
NAGLUN-acetyl-alpha-glucosaminidase. (741 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
HMX2H6 family homeobox 2. (274 aa)
OCM2Uncharacterized protein; Belongs to the parvalbumin family. (132 aa)
PTPRQProtein tyrosine phosphatase receptor type Q. (2343 aa)
GSDMEGasdermin E. (495 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (410 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (932 aa)
LRRC1Leucine rich repeat containing 1. (517 aa)
IFT88Intraflagellar transport 88. (825 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (670 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
CCM2PID domain-containing protein. (476 aa)
ENSCHIP00000021920Uncharacterized protein. (107 aa)
BCRBCR activator of RhoGEF and GTPase. (1130 aa)
PAX8Paired box 8. (457 aa)
MCM2DNA helicase; Belongs to the MCM family. (1061 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
TMIETransmembrane inner ear. (256 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
PCDH15Protocadherin related 15. (1951 aa)
OTOP1Otopetrin 1. (613 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
SCRIBScribble planar cell polarity protein. (1582 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
WDPCPWD repeat containing planar cell polarity effector. (676 aa)
GRHL3Grainyhead like transcription factor 3. (600 aa)
MCOLN3Mucolipin 3. (553 aa)
POU4F3POU domain protein. (338 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (817 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1289 aa)
BMPERBMP binding endothelial regulator. (685 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1261 aa)
TFAP2ATranscription factor AP-2 alpha. (485 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
Server load: low (34%) [HD]