Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADAM8 | MMP8 | ENSCHIP00000020655 | ENSCHIP00000033380 | ADAM metallopeptidase domain 8. | Matrix metallopeptidase 8. | 0.429 |
| APP | C3 | ENSCHIP00000032622 | ENSCHIP00000004329 | Amyloid beta precursor protein. | Complement C3. | 0.520 |
| APP | IFNG | ENSCHIP00000032622 | ENSCHIP00000016152 | Amyloid beta precursor protein. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. | 0.442 |
| APP | IL1B | ENSCHIP00000032622 | ENSCHIP00000029274 | Amyloid beta precursor protein. | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | 0.635 |
| APP | PARK7 | ENSCHIP00000032622 | ENSCHIP00000025227 | Amyloid beta precursor protein. | Parkinsonism associated deglycase. | 0.451 |
| APP | SNCA | ENSCHIP00000032622 | ENSCHIP00000009503 | Amyloid beta precursor protein. | Alpha-synuclein; Belongs to the synuclein family. | 0.908 |
| APP | TLR4 | ENSCHIP00000032622 | ENSCHIP00000019512 | Amyloid beta precursor protein. | TIR domain-containing protein; Belongs to the Toll-like receptor family. | 0.557 |
| APP | TNF | ENSCHIP00000032622 | ENSCHIP00000004561 | Amyloid beta precursor protein. | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | 0.606 |
| APP | TNFRSF1A | ENSCHIP00000032622 | ENSCHIP00000010109 | Amyloid beta precursor protein. | TNF receptor superfamily member 1A. | 0.474 |
| APP | TREM2 | ENSCHIP00000032622 | ENSCHIP00000003876 | Amyloid beta precursor protein. | Triggering receptor expressed on myeloid cells 2. | 0.736 |
| C3 | APP | ENSCHIP00000004329 | ENSCHIP00000032622 | Complement C3. | Amyloid beta precursor protein. | 0.520 |
| C3 | CD81 | ENSCHIP00000004329 | ENSCHIP00000005620 | Complement C3. | Tetraspanin. | 0.467 |
| C3 | IFNG | ENSCHIP00000004329 | ENSCHIP00000016152 | Complement C3. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. | 0.468 |
| C3 | IL1B | ENSCHIP00000004329 | ENSCHIP00000029274 | Complement C3. | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | 0.588 |
| C3 | TLR9 | ENSCHIP00000004329 | ENSCHIP00000029061 | Complement C3. | TIR domain-containing protein. | 0.425 |
| C3 | TNF | ENSCHIP00000004329 | ENSCHIP00000004561 | Complement C3. | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | 0.469 |
| CASP1 | ENSCHIP00000027556 | ENSCHIP00000011226 | ENSCHIP00000027556 | Uncharacterized protein; Belongs to the peptidase C14A family. | Uncharacterized protein; Belongs to the peptidase C14A family. | 0.472 |
| CASP1 | IFNG | ENSCHIP00000011226 | ENSCHIP00000016152 | Uncharacterized protein; Belongs to the peptidase C14A family. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. | 0.772 |
| CASP1 | IL18 | ENSCHIP00000011226 | ENSCHIP00000023420 | Uncharacterized protein; Belongs to the peptidase C14A family. | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. | 0.974 |
| CASP1 | IL1B | ENSCHIP00000011226 | ENSCHIP00000029274 | Uncharacterized protein; Belongs to the peptidase C14A family. | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | 0.990 |
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