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| | TAL1 | TAL bHLH transcription factor 1, erythroid differentiation factor. (328 aa) |
| | ENSCHIP00000000372 | Uncharacterized protein. (176 aa) |
| | EREG | Epiregulin. (163 aa) |
| | SEMA4D | Semaphorin 4D; Belongs to the semaphorin family. (863 aa) |
| | IL5 | Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (129 aa) |
| | NRG1 | Neuregulin 1. (700 aa) |
| | ADRA2A | Adrenoceptor alpha 2A. (468 aa) |
| | TNFRSF18 | Uncharacterized protein. (243 aa) |
| | MLST8 | MTOR associated protein, LST8 homolog. (338 aa) |
| | EFNA1 | Ephrin A1; Belongs to the ephrin family. (205 aa) |
| | HPX | Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (459 aa) |
| | SRC | Tyrosine-protein kinase. (538 aa) |
| | AFAP1L2 | Actin filament associated protein 1 like 2. (841 aa) |
| | FGFR3 | Receptor protein-tyrosine kinase. (710 aa) |
| | CLEC6A | C-type lectin domain containing 6A. (206 aa) |
| | IL6ST | Interleukin 6 signal transducer. (918 aa) |
| | CSF2 | Granulocyte-macrophage colony stimulating factor. (144 aa) |
| | FBXW9 | F-box and WD repeat domain containing 9. (458 aa) |
| | LOC102173987 | Uncharacterized protein. (349 aa) |
| | BMP6 | Bone morphogenetic protein 6. (496 aa) |
| | CSF1R | Colony stimulating factor 1 receptor. (958 aa) |
| | STAP1 | Signal transducing adaptor family member 1. (300 aa) |
| | ALKAL1 | Uncharacterized protein. (93 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (736 aa) |
| | ERBB4 | Protein kinase domain-containing protein. (462 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) |
| | EPO | Erythropoietin. (208 aa) |
| | CASS4 | Cas scaffold protein family member 4. (811 aa) |
| | KITLG | Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family. (274 aa) |
| | EPHA4 | EPH receptor A4. (986 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa) |
| | LRP4 | LDL receptor related protein 4. (1901 aa) |
| | NOD2 | Uncharacterized protein. (982 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (155 aa) |
| | BTC | Betacellulin. (178 aa) |
| | THBS4 | Thrombospondin 4. (965 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (161 aa) |
| | FBXW7 | F-box and WD repeat domain containing 7. (705 aa) |
| | CD40 | CD40 molecule. (280 aa) |
| | LRRK1 | Leucine rich repeat kinase 1. (2039 aa) |
| | HCLS1 | Hematopoietic cell-specific Lyn substrate 1. (471 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (157 aa) |
| | LRP8 | LDL receptor related protein 8. (1011 aa) |
| | DGKQ | Diacylglycerol kinase theta. (785 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1707 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (238 aa) |
| | HBEGF | Heparin binding EGF like growth factor. (208 aa) |
| | PLPP3 | acidPPc domain-containing protein. (312 aa) |
| | ISL1 | ISL LIM homeobox 1. (349 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1067 aa) |
| | CSPG4 | Chondroitin sulfate proteoglycan 4. (2340 aa) |
| | LYN | Tyrosine-protein kinase. (512 aa) |
| | KIT | Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (974 aa) |
| | SRCIN1 | SRC kinase signaling inhibitor 1. (1246 aa) |
| | NCF1 | Neutrophil cytosolic factor 1. (392 aa) |
| | HES5 | Hes family bHLH transcription factor 5. (165 aa) |
| | NEURL1 | Neuralized E3 ubiquitin protein ligase 1. (574 aa) |
| | ABL1 | Tyrosine-protein kinase. (1151 aa) |
| | NOX4 | NADPH oxidase 4. (578 aa) |
| | CD44 | CD44 molecule (Indian blood group). (715 aa) |
| | NEDD9 | Neural precursor cell expressed, developmentally down-regulated 9. (826 aa) |
| | ADRA1A | Adrenoceptor alpha 1A. (466 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | IGF2 | Insulin-like growth factor II. (179 aa) |
| | EPGN | Epithelial mitogen. (136 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1208 aa) |
| | ENSCHIP00000022555 | ARL2_Bind_BART domain-containing protein. (152 aa) |
| | IL34 | Interleukin 34. (233 aa) |
| | ALKAL2 | ALK and LTK ligand 2. (151 aa) |
| | LOC106502311 | Uncharacterized protein. (148 aa) |
| | ENSCHIP00000021944 | ARL2_Bind_BART domain-containing protein. (139 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa) |
| | OSM | Oncostatin M. (239 aa) |
| | HAX1 | HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (279 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (135 aa) |
| | PECAM1 | Platelet and endothelial cell adhesion molecule 1. (739 aa) |
| | IGF1 | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (188 aa) |
| | ARHGEF2 | Rho/Rac guanine nucleotide exchange factor 2. (986 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (537 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (524 aa) |
| | PTPN1 | Tyrosine-protein phosphatase non-receptor type. (424 aa) |
| | BANK1 | B cell scaffold protein with ankyrin repeats 1. (771 aa) |
| | ENPP2 | Ectonucleotide pyrophosphatase/phosphodiesterase 2. (884 aa) |
| | ANGPT4 | Angiopoietin 4. (498 aa) |
| | GHRL | Appetite-regulating hormone; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation (By similarity). (133 aa) |
| | TGFA | Transforming growth factor alpha. (215 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (280 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (786 aa) |
| | LOC102190507 | Uncharacterized protein. (139 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa) |
| | CLCF1 | Cardiotrophin like cytokine factor 1. (220 aa) |
| | IL11 | Interleukin 11. (191 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (331 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa) |
| | HTR2A | 5-hydroxytryptamine receptor 2A. (470 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (166 aa) |
| | RELN | Reelin. (3469 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa) |
| | PARP9 | Poly(ADP-ribose) polymerase family member 9. (855 aa) |
| | AREG | Amphiregulin. (264 aa) |
| | ANGPT1 | Angiopoietin 1. (488 aa) |
| | GRM5 | Glutamate metabotropic receptor 5. (936 aa) |
| | GAS6 | Growth arrest specific 6. (671 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | ABI1 | Abl interactor 1. (508 aa) |
| | CSF3 | Colony stimulating factor 3. (226 aa) |
| | CTF1 | Cardiotrophin 1. (202 aa) |
| | ITGA5 | Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1100 aa) |
| | VTN | SMB domain-containing protein. (475 aa) |
| | CRLF1 | Cytokine receptor like factor 1. (447 aa) |
| | PRNP | Major prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...] (256 aa) |
| | LIF | LIF interleukin 6 family cytokine. (202 aa) |
| | UNC119 | Unc-119 lipid binding chaperone. (248 aa) |
| | CD74 | CD74 molecule. (261 aa) |
| | ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1344 aa) |
| | ADAM17 | ADAM metallopeptidase domain 17. (829 aa) |
| | IL31RA | Interleukin 31 receptor A. (714 aa) |
| | EFNA5 | Ephrin A5; Belongs to the ephrin family. (205 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (449 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa) |
| | LOC102185312 | Uncharacterized protein. (2397 aa) |
| | IL6R | Interleukin 6 receptor. (441 aa) |
| | NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (266 aa) |
| | ARL2BP | ARL2_Bind_BART domain-containing protein. (146 aa) |
| | SYK | Spleen associated tyrosine kinase. (636 aa) |
| | SH2D1B | SH2 domain containing 1B. (133 aa) |
| | ENSCHIP00000008932 | Uncharacterized protein. (166 aa) |
| | TNFSF18 | TNF superfamily member 18. (194 aa) |
| | IL23A | Interleukin 23 subunit alpha. (190 aa) |
| | AGT | Angiotensinogen; Belongs to the serpin family. (476 aa) |
| | CNTF | Ciliary neurotrophic factor. (199 aa) |
| | GREM1 | Gremlin. (184 aa) |
| | ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1481 aa) |
| | CD81 | Tetraspanin. (236 aa) |
| | HGF | Hepatocyte growth factor; Belongs to the peptidase S1 family. (814 aa) |
| | CD80 | CD80 molecule. (302 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (214 aa) |
| | PIBF1 | Progesterone immunomodulatory binding factor 1. (757 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | GATA1 | GATA binding protein 1. (413 aa) |
| | ALK | Tyrosine-protein kinase receptor. (1309 aa) |
| | NRP1 | Neuropilin; Belongs to the neuropilin family. (923 aa) |
| | TREM2 | Triggering receptor expressed on myeloid cells 2. (230 aa) |
