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| | NKAP | NFKB activating protein. (370 aa) |
| | ZMIZ1 | Zinc finger MIZ-type containing 1. (1072 aa) |
| | LOC102183503 | AIG1-type G domain-containing protein. (309 aa) |
| | GIMAP5 | AIG1-type G domain-containing protein. (298 aa) |
| | ENSCHIP00000000943 | Uncharacterized protein. (356 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (219 aa) |
| | SOCS5 | Suppressor of cytokine signaling 5. (536 aa) |
| | TNFSF13B | Tumor necrosis factor superfamily member 13b; Belongs to the tumor necrosis factor family. (280 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) |
| | TNFSF9 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (252 aa) |
| | HSPD1 | Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (573 aa) |
| | CD5 | CD5 molecule. (505 aa) |
| | VSIR | V-set immunoregulatory receptor. (312 aa) |
| | FAM49B | Uncharacterized protein. (350 aa) |
| | IL2RG | Fibronectin type-III domain-containing protein. (378 aa) |
| | RHOH | Ras homolog family member H. (191 aa) |
| | ENSCHIP00000003765 | AIG1-type G domain-containing protein. (277 aa) |
| | IL6ST | Interleukin 6 signal transducer. (918 aa) |
| | EFNB1 | Ephrin B1; Belongs to the ephrin family. (373 aa) |
| | SOX12 | Transcription factor SOX. (314 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (209 aa) |
| | ZBTB16 | Uncharacterized protein. (673 aa) |
| | HHLA2 | HERV-H LTR-associating 2. (419 aa) |
| | ENSCHIP00000004646 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (118 aa) |
| | ENSCHIP00000004806 | Ig-like domain-containing protein. (241 aa) |
| | SLAMF1 | Ig-like domain-containing protein. (338 aa) |
| | HLA-DMA | Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (278 aa) |
| | CD80 | CD80 molecule. (302 aa) |
| | LOC102186442 | Ig-like domain-containing protein. (290 aa) |
| | CD81 | Tetraspanin. (236 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1178 aa) |
| | MYB | MYB proto-oncogene, transcription factor. (640 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (773 aa) |
| | NCK2 | Cytoplasmic protein. (376 aa) |
| | HLA-DOB | Major histocompatibility complex, class II, DO beta. (270 aa) |
| | CAHI-DQA2 | Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa) |
| | IL36B | Interleukin-1. (158 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa) |
| | IL23A | Interleukin 23 subunit alpha. (190 aa) |
| | PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa) |
| | DHPS | Uncharacterized protein. (369 aa) |
| | SPTA1 | Spectrin alpha, erythrocytic 1. (2402 aa) |
| | TGFBR2 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (550 aa) |
| | BCL10 | BCL10 immune signaling adaptor. (230 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | SYK | Spleen associated tyrosine kinase. (636 aa) |
| | ZAP70 | Tyrosine-protein kinase. (622 aa) |
| | RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | CD3E | CD3e molecule. (194 aa) |
| | NCK1 | Cytoplasmic protein. (377 aa) |
| | SIRPA | Uncharacterized protein. (506 aa) |
| | SOX13 | SRY-box transcription factor 13. (592 aa) |
| | LOC108635823 | AIG1-type G domain-containing protein. (297 aa) |
| | LOC106503481 | Ig-like domain-containing protein. (274 aa) |
| | HLA-DRA | Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (253 aa) |
| | IL7 | Interleukin 7. (181 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa) |
| | LOC102179937 | Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa) |
| | ENSCHIP00000011371 | Uncharacterized protein. (193 aa) |
| | LCK | Tyrosine-protein kinase. (509 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (416 aa) |
| | RHOA | Ras-like protein family member A. (193 aa) |
| | CD74 | CD74 molecule. (261 aa) |
| | IL4I1 | Interleukin 4 induced 1. (582 aa) |
| | HLX | H2.0 like homeobox. (488 aa) |
| | FOXP3 | Forkhead box P3. (463 aa) |
| | HLA-DOA | Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (332 aa) |
| | PTPN22 | Protein tyrosine phosphatase non-receptor type 22. (795 aa) |
| | ENSCHIP00000012902 | Ig-like domain-containing protein. (249 aa) |
| | LGALS1 | Galectin-1; Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Has hemaglutinating activity towards human erythrocytes. (136 aa) |
| | DOCK8 | Dedicator of cytokinesis 8; Belongs to the DOCK family. (2091 aa) |
| | RARA | Retinoic acid receptor alpha. (462 aa) |
| | IL27RA | Interleukin 27 receptor subunit alpha. (655 aa) |
| | TNFSF11 | Tumor necrosis factor ligand superfamily member. (316 aa) |
| | GLI3 | GLI family zinc finger 3. (1614 aa) |
| | EPHB6 | EPH receptor B6. (1011 aa) |
| | BAD | BCL2 associated agonist of cell death. (198 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa) |
| | LOC102171800 | Uncharacterized protein. (286 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (573 aa) |
| | ENSCHIP00000015226 | KH type-2 domain-containing protein. (204 aa) |
| | DRB3 | Ig-like domain-containing protein. (269 aa) |
| | CD86 | Ig-like domain-containing protein. (289 aa) |
| | PRKCQ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (711 aa) |
| | LOC102180664 | Ig-like domain-containing protein. (266 aa) |
| | ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (942 aa) |
| | SART1 | Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (796 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (166 aa) |
| | IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa) |
| | MALT1 | MALT1 paracaspase. (830 aa) |
| | BMI1 | RING-type domain-containing protein. (437 aa) |
| | LOC102170474 | Uncharacterized protein. (238 aa) |
| | AMBRA1 | Autophagy and beclin 1 regulator 1. (1300 aa) |
| | TNFRSF13C | TNF receptor superfamily member 13C. (177 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (331 aa) |
| | SLC7A1 | Solute carrier family 7 member 1. (629 aa) |
| | HAVCR2 | Hepatitis A virus cellular receptor 2. (280 aa) |
| | CD274 | CD274 molecule. (289 aa) |
| | CD83 | CD83 molecule. (199 aa) |
| | VNN1 | Vanin 1. (529 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (280 aa) |
| | FCHO1 | FCH domain only 1. (887 aa) |
| | FLOT2 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (445 aa) |
| | RASAL3 | RAS protein activator like 3. (1013 aa) |
| | FOXO3 | Forkhead box O3. (672 aa) |
| | ENSCHIP00000019274 | Ig-like domain-containing protein. (253 aa) |
| | CCL19 | C-C motif chemokine. (102 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (537 aa) |
| | TYK2 | Tyrosine-protein kinase. (1186 aa) |
| | AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa) |
| | IGF1 | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (188 aa) |
| | CCDC88B | Coiled-coil domain containing 88B. (1455 aa) |
| | CCR7 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (379 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (135 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (827 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (192 aa) |
| | VTCN1 | V-set domain containing T cell activation inhibitor 1. (270 aa) |
| | TNFSF4 | TNF superfamily member 4; Belongs to the tumor necrosis factor family. (182 aa) |
| | CD6 | CD6 molecule. (672 aa) |
| | ZBTB1 | Zinc finger and BTB domain containing 1. (644 aa) |
| | BTNL2 | Butyrophilin like 2. (522 aa) |
| | DUSP10 | Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa) |
| | ENSCHIP00000022485 | AIG1-type G domain-containing protein. (295 aa) |
| | SASH3 | SAM and SH3 domain containing 3. (380 aa) |
| | GPAM | Glycerol-3-phosphate acyltransferase 1, mitochondrial. (844 aa) |
| | CBFB | Core-binding factor subunit beta. (187 aa) |
| | IL7R | Interleukin 7 receptor. (459 aa) |
| | LOC102183203 | Amine oxidase. (517 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | IGF2 | Insulin-like growth factor II. (179 aa) |
| | CARD11 | Caspase recruitment domain family member 11. (1154 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | LOC102178618 | AIG1-type G domain-containing protein. (214 aa) |
| | DPP4 | Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (767 aa) |
| | ENSCHIP00000024183 | Uncharacterized protein. (207 aa) |
| | CORO1A | Coronin; Belongs to the WD repeat coronin family. (461 aa) |
| | CD27 | CD27 molecule. (270 aa) |
| | ABL1 | Tyrosine-protein kinase. (1151 aa) |
| | STAT5B | Signal transducer and activator of transcription. (808 aa) |
| | ZP3 | ZP domain-containing protein. (432 aa) |
| | LOC102186727 | Ig-like domain-containing protein; Belongs to the MHC class II family. (322 aa) |
| | STAT5A | Signal transducer and activator of transcription. (810 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1067 aa) |
| | EGR3 | Early growth response 3. (387 aa) |
| | CD47 | CD47 molecule. (321 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (238 aa) |
| | PYCARD | PYD and CARD domain containing. (196 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (157 aa) |
| | LOC108633275 | TNF_2 domain-containing protein. (230 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa) |
| | XBP1 | BZIP domain-containing protein. (261 aa) |
| | SELENOK | Selenoprotein K. (85 aa) |
| | AIF1 | Allograft inflammatory factor 1. (147 aa) |
| | THY1 | Thy-1 cell surface antigen. (161 aa) |
| | PDCD1LG2 | Programmed cell death 1 ligand 2. (296 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (161 aa) |
| | CD28 | CD28 molecule. (228 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (155 aa) |
| | NOD2 | Uncharacterized protein. (982 aa) |
| | ICOS | Inducible T cell costimulator. (209 aa) |
| | PIK3R6 | Phosphoinositide-3-kinase regulatory subunit 6. (762 aa) |
| | GATA3 | GATA binding protein 3. (467 aa) |
| | KITLG | Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family. (274 aa) |
| | LEF1 | HMG box domain-containing protein. (430 aa) |
| | IGFBP2 | Uncharacterized protein. (326 aa) |
| | SHB | SH2 domain-containing protein. (507 aa) |
| | LOC102180664-2 | Ig-like domain-containing protein. (268 aa) |
| | ZBTB7B | Zinc finger and BTB domain containing 7B. (539 aa) |
| | ENSCHIP00000031698 | Uncharacterized protein. (321 aa) |
| | IL1RL2 | Interleukin 1 receptor like 2. (552 aa) |
| | ZP4 | Zona pellucida glycoprotein 4. (531 aa) |
| | NFKBIZ | Molecule possessing ankyrin-repeats induced by lipopolysaccharide. (719 aa) |
| | BCL6 | BCL6 transcription repressor. (706 aa) |
| | LOC102187998 | Ig-like domain-containing protein. (262 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (527 aa) |
| | IL12RB2 | Interleukin 12 receptor subunit beta 2. (877 aa) |
| | TFRC | Transferrin receptor. (790 aa) |
| | ADA | Adenosine deaminase. (400 aa) |
| | IL12RB1 | Interleukin 12 receptor subunit beta 1. (730 aa) |
| | EFNB3 | Ephrin B3; Belongs to the ephrin family. (340 aa) |
