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SHLD2 | Shieldin complex subunit 2. (918 aa) | ||||
SMCHD1 | Structural maintenance of chromosomes flexible hinge domain containing 1. (1987 aa) | ||||
TIPIN | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (289 aa) | ||||
H1-5 | Histone cluster 1 H1 family member b. (226 aa) | ||||
ENSCHIP00000001374 | Uncharacterized protein. (222 aa) | ||||
ENSCHIP00000001595 | Uncharacterized protein. (333 aa) | ||||
DACH1 | Dachshund family transcription factor 1. (761 aa) | ||||
HNRNPU | Heterogeneous nuclear ribonucleoprotein U. (806 aa) | ||||
NUDT16L1 | Nudix hydrolase 16 like 1. (211 aa) | ||||
CDKN1A | Cyclin dependent kinase inhibitor 1A. (161 aa) | ||||
SRC | Tyrosine-protein kinase. (538 aa) | ||||
H1-4 | Histone cluster 1 H1 family member e. (219 aa) | ||||
RNF169 | Ring finger protein 169. (708 aa) | ||||
RAD50 | Zinc-hook domain-containing protein. (1332 aa) | ||||
GZMA | Granzyme A; Belongs to the peptidase S1 family. (259 aa) | ||||
NIBAN2 | Niban apoptosis regulator 2. (744 aa) | ||||
TNKS | Poly [ADP-ribose] polymerase. (1327 aa) | ||||
SUB1 | SUB1 regulator of transcription. (127 aa) | ||||
LOC102170015 | Uncharacterized protein. (384 aa) | ||||
TEN1 | Uncharacterized protein. (123 aa) | ||||
HSF1 | HSF_DOMAIN domain-containing protein. (537 aa) | ||||
RECQL5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (991 aa) | ||||
ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1481 aa) | ||||
ENSCHIP00000006184 | Uncharacterized protein. (96 aa) | ||||
TP53BP1 | Tumor protein p53 binding protein 1. (1966 aa) | ||||
BLM | BLM RecQ like helicase. (1429 aa) | ||||
DFFB | DNA fragmentation factor subunit beta. (370 aa) | ||||
H1-6 | Histone cluster 1 H1 family member t. (210 aa) | ||||
TIMELESS | Timeless circadian regulator. (1206 aa) | ||||
H1-3 | Histone cluster 1 H1 family member d. (221 aa) | ||||
MAD2L2 | Mitotic arrest deficient 2 like 2. (195 aa) | ||||
NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (754 aa) | ||||
LOC102181348 | H15 domain-containing protein. (210 aa) | ||||
DCP2 | Decapping mRNA 2. (423 aa) | ||||
LOC102188481 | Uncharacterized protein. (379 aa) | ||||
TERF1 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (436 aa) | ||||
LOC102189034 | Uncharacterized protein. (320 aa) | ||||
RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa) | ||||
H1-1 | Histone cluster 1 H1 family member a. (218 aa) | ||||
TRIM28 | Tripartite motif containing 28. (837 aa) | ||||
CDT1 | Chromatin licensing and DNA replication factor 1. (637 aa) | ||||
ZNF830 | Zinc finger protein 830. (361 aa) | ||||
ENSCHIP00000010204 | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (275 aa) | ||||
LOC102184761 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (260 aa) | ||||
TRIP12 | Thyroid hormone receptor interactor 12. (2067 aa) | ||||
MEN1 | Menin 1. (609 aa) | ||||
WAPL | WAPL cohesin release factor. (1193 aa) | ||||
POLQ | DNA polymerase theta. (2587 aa) | ||||
HMGA2 | Uncharacterized protein. (104 aa) | ||||
RTEL1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1212 aa) | ||||
MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1361 aa) | ||||
OTUB1 | Ubiquitin thioesterase. (271 aa) | ||||
FOXP3 | Forkhead box P3. (463 aa) | ||||
NRM | Nurim. (262 aa) | ||||
PIF1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (649 aa) | ||||
POT1 | Protection of telomeres 1. (785 aa) | ||||
AUNIP | Aurora kinase A and ninein interacting protein. (357 aa) | ||||
SHLD1 | Shieldin complex subunit 1. (206 aa) | ||||
TSPYL2 | TSPY like 2; Belongs to the nucleosome assembly protein (NAP) family. (699 aa) | ||||
UBQLN4 | Ubiquilin 4. (601 aa) | ||||
H1-8 | H1 histone family member O oocyte specific. (333 aa) | ||||
THOC1 | THO complex 1. (657 aa) | ||||
FANCB | Uncharacterized protein. (447 aa) | ||||
ENSCHIP00000015226 | KH type-2 domain-containing protein. (204 aa) | ||||
PARP3 | Poly [ADP-ribose] polymerase. (525 aa) | ||||
FBH1 | F-box DNA helicase 1. (1048 aa) | ||||
ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3058 aa) | ||||
LOC102178151 | Uncharacterized protein. (163 aa) | ||||
CCDC197 | Coiled-coil domain containing 197. (288 aa) | ||||
SLX4 | SLX4 structure-specific endonuclease subunit. (1752 aa) | ||||
KMT2A | Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3871 aa) | ||||
ENSCHIP00000018363 | Uncharacterized protein. (331 aa) | ||||
GDF2 | Growth differentiation factor 2. (430 aa) | ||||
MAGEF1 | MAGE family member F1. (299 aa) | ||||
CGAS | Cyclic GMP-AMP synthase. (511 aa) | ||||
ANKRD1 | Ankyrin repeat domain 1. (319 aa) | ||||
CYREN | Cell cycle regulator of NHEJ. (144 aa) | ||||
STN1 | CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (370 aa) | ||||
GMNN | Geminin DNA replication inhibitor. (186 aa) | ||||
EXOSC10 | Exosome component 10. (844 aa) | ||||
BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa) | ||||
RIF1 | Replication timing regulatory factor 1. (2486 aa) | ||||
MCIDAS | Multiciliate differentiation and DNA synthesis associated cell cycle protein. (374 aa) | ||||
ENSCHIP00000022338 | Uncharacterized protein. (300 aa) | ||||
DONSON | Downstream neighbor of SON. (561 aa) | ||||
OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2. (234 aa) | ||||
XRCC1 | X-ray repair cross complementing 1. (632 aa) | ||||
RAD17 | RAD17 checkpoint clamp loader component. (709 aa) | ||||
LOC102175542 | Uncharacterized protein. (307 aa) | ||||
UBR5 | Ubiquitin protein ligase E3 component n-recognin 5. (2801 aa) | ||||
CERS1 | TLC domain-containing protein. (333 aa) | ||||
TERF2IP | Uncharacterized protein. (400 aa) | ||||
TNKS2 | Poly [ADP-ribose] polymerase. (1166 aa) | ||||
BRCA2 | BRCA2 DNA repair associated. (3405 aa) | ||||
ENSCHIP00000024183 | Uncharacterized protein. (207 aa) | ||||
KLHL15 | Kelch like family member 15. (604 aa) | ||||
RMI2 | Uncharacterized protein. (161 aa) | ||||
RADX | RPA1 related single stranded DNA binding protein, X-linked. (764 aa) | ||||
H1-2 | Histone cluster 1 H1 family member c. (227 aa) | ||||
MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (946 aa) | ||||
ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa) | ||||
SMG6 | SMG6 nonsense mediated mRNA decay factor. (1411 aa) | ||||
XRCC5 | X-ray repair cross complementing 5. (736 aa) | ||||
ENPP7 | Ectonucleotide pyrophosphatase/phosphodiesterase 7. (435 aa) | ||||
ERCC4 | ERCC excision repair 4, endonuclease catalytic subunit. (916 aa) | ||||
OGG1 | 8-oxoguanine DNA glycosylase. (345 aa) | ||||
PARPBP | PARP1 binding protein. (580 aa) | ||||
GMNC | Geminin coiled-coil domain containing. (336 aa) | ||||
CDAN1 | Codanin 1. (1230 aa) | ||||
TINF2 | TERF1 interacting nuclear factor 2. (458 aa) | ||||
LIG3 | DNA ligase. (1004 aa) | ||||
TERF2 | Telomeric repeat binding factor 2. (543 aa) | ||||
CTC1 | CST telomere replication complex component 1. (1210 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa) | ||||
GATA3 | GATA binding protein 3. (467 aa) | ||||
HNRNPA1 | Uncharacterized protein. (320 aa) | ||||
SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (930 aa) | ||||
NDFIP1 | Nedd4 family interacting protein 1. (221 aa) | ||||
ACD | ACD shelterin complex subunit and telomerase recruitment factor. (458 aa) | ||||
ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (294 aa) | ||||
ZRANB3 | Zinc finger RANBP2-type containing 3. (1070 aa) | ||||
ENSCHIP00000031621 | Uncharacterized protein. (159 aa) | ||||
NAT10 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1026 aa) | ||||
PDS5A | PDS5 cohesin associated factor A. (1337 aa) | ||||
DNMT3L | PHD-type domain-containing protein. (390 aa) | ||||
BCL6 | BCL6 transcription repressor. (706 aa) | ||||
PINX1 | PIN2 (TERF1) interacting telomerase inhibitor 1. (312 aa) | ||||
MSH3 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1119 aa) | ||||
ADIPOQ | C1q domain-containing protein. (283 aa) | ||||
FBXO5 | F-box protein 5. (448 aa) | ||||
ACVRL1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) | ||||
HELB | DNA helicase B. (1077 aa) | ||||
FLCN | UDENN FLCN/SMCR8-type domain-containing protein. (579 aa) |