STRINGSTRING
CFHR5 CFHR5 ZFPM1 ZFPM1 PLCL2 PLCL2 EIF4G1 EIF4G1 GEMIN2 GEMIN2 MYOD1 MYOD1 TCF7L2 TCF7L2 DAB2 DAB2 NEK2 NEK2 ZFP90 ZFP90 NOG NOG DDRGK1 DDRGK1 ENSCHIP00000005210 ENSCHIP00000005210 CRK CRK KDM1A KDM1A GATA1 GATA1 ZNF462 ZNF462 LRRC6 LRRC6 PLXND1 PLXND1 MFNG MFNG MEPCE MEPCE TNKS TNKS NIBAN2 NIBAN2 TERT TERT MED25 MED25 BTAF1 BTAF1 RIPOR2 RIPOR2 GZMA GZMA SPAG8 SPAG8 ENSCHIP00000003109 ENSCHIP00000003109 BDNF BDNF CDON CDON DZIP1 DZIP1 LOC106502849 LOC106502849 SRC SRC CDKN1A CDKN1A ADAM15 ADAM15 EIF3E EIF3E RTL8C RTL8C ENSCHIP00000019700 ENSCHIP00000019700 MARK3 MARK3 RIPK2 RIPK2 ATP2A3 ATP2A3 CKMT1A CKMT1A HABP4 HABP4 PLAUR PLAUR CAMK1 CAMK1 HES1 HES1 S100A10 S100A10 ENSCHIP00000018388 ENSCHIP00000018388 EP300 EP300 NME1 NME1 ZNF304 ZNF304 CRMP1 CRMP1 TFIP11 TFIP11 IRF4 IRF4 ENSCHIP00000017024 ENSCHIP00000017024 IFIT2 IFIT2 USP33 USP33 DNAJB2 DNAJB2 MMP9 MMP9 HDAC5 HDAC5 BAG2 BAG2 IDE IDE CLIC2 CLIC2 IFNG IFNG ADD2 ADD2 BAX BAX ANKRD33 ANKRD33 PARK2 PARK2 PKD1 PKD1 BCL3 BCL3 ROCK1 ROCK1 WNT3A WNT3A WNT5A WNT5A PARP9 PARP9 MAPK3 MAPK3 ENSCHIP00000015495 ENSCHIP00000015495 NMD3 NMD3 ARRB2 ARRB2 SUMO3 SUMO3 TRAF6 TRAF6 NPHP3 NPHP3 NUCKS1 NUCKS1 E2F1 E2F1 RACK1 RACK1 FBXW7 FBXW7 NFATC4 NFATC4 CTNNBIP1 CTNNBIP1 KRIT1 KRIT1 ZNF618 ZNF618 EBF2 EBF2 DTX3L DTX3L TMC8 TMC8 FLOT1 FLOT1 LOC102189480 LOC102189480 PAX6 PAX6 AKT1 AKT1 BLK BLK MAPRE1 MAPRE1 SMO SMO LFNG LFNG ENSCHIP00000026982 ENSCHIP00000026982 DTNBP1 DTNBP1 ERCC2 ERCC2 LOC102180576 LOC102180576 AURKB AURKB CLN5 CLN5 CBLB CBLB AURKA AURKA TRIM21 TRIM21 LRP1 LRP1 SPON1 SPON1 LHX2 LHX2 NSD1 NSD1 SPPL3 SPPL3 CDK9 CDK9 CCPG1 CCPG1 TTBK2 TTBK2 SMARCD3 SMARCD3 RSF1 RSF1 MET MET EPHA4 EPHA4 GATA3 GATA3 HIP1R HIP1R ENSCHIP00000030535 ENSCHIP00000030535 PSEN1 PSEN1 ATP2A2 ATP2A2 LEF1 LEF1 ACD ACD CTNNB1 CTNNB1 TTC36 TTC36 PDGFB PDGFB RAPGEF2 RAPGEF2 STYX STYX CDK5 CDK5 RFNG RFNG GTF2B GTF2B TEX14 TEX14 ARHGEF7 ARHGEF7 CPNE1 CPNE1 NES NES PINX1 PINX1 APP APP ADIPOQ ADIPOQ PPP3CA PPP3CA SYMPK SYMPK HEY2 HEY2 MMP8 MMP8 UBASH3B UBASH3B ENSCHIP00000033427 ENSCHIP00000033427 FBXW9 FBXW9 HOPX HOPX RB1 RB1 JUN JUN LDLRAP1 LDLRAP1 POU4F1 POU4F1 STK4 STK4 HAND1 HAND1 C6H4orf3 C6H4orf3 ZBTB7C ZBTB7C NVL NVL ENSCHIP00000000967 ENSCHIP00000000967 TMBIM6 TMBIM6 ENSCHIP00000000419 ENSCHIP00000000419 FMR1 FMR1 EDF1 EDF1 DOT1L DOT1L SRI SRI EPHB6 EPHB6 TRIM6 TRIM6 BAMBI BAMBI DVL1 DVL1 TNFSF11 TNFSF11 CSF3 CSF3 PTPRF PTPRF RARA RARA GSK3B GSK3B VTN VTN EPB41 EPB41 TFAP4 TFAP4 ZMPSTE24 ZMPSTE24 AMFR AMFR LIF LIF EPB41L5 EPB41L5 MSX1 MSX1 CDC42 CDC42 PABPN1L PABPN1L LOC108634550 LOC108634550 HMGA2 HMGA2 AGER AGER SMAD3 SMAD3 WAPL WAPL LARP6 LARP6 MEN1 MEN1 NEUROD1 NEUROD1 TXN TXN PEX19 PEX19 ACTB ACTB PLCL1 PLCL1 LOC102184761 LOC102184761 EFHB EFHB BMP2 BMP2 PIN1 PIN1 PON1 PON1 CTHRC1 CTHRC1 DHRS7B DHRS7B DHX9 DHX9 SNAPIN SNAPIN LOC108634461 LOC108634461 LOC102185270 LOC102185270 IGF1 IGF1 DERL1 DERL1 RALB RALB SMAD4 SMAD4 LDOC1 LDOC1 CAV1 CAV1 ILRUN ILRUN ITGA4 ITGA4 RNF220 RNF220 GMNN GMNN SIRT2 SIRT2 ITGB1BP1 ITGB1BP1 ENSCHIP00000021995 ENSCHIP00000021995 NCBP1 NCBP1 SMAD2 SMAD2 CLDN5 CLDN5 CTBP2 CTBP2 PBXIP1 PBXIP1 LRPAP1 LRPAP1 CDT1 CDT1 TRIM28 TRIM28 ENSCHIP00000009674 ENSCHIP00000009674 HAND2 HAND2 TAF10 TAF10 XIRP1 XIRP1 TRIB3 TRIB3 MDFI MDFI RPL11 RPL11 PSME3IP1 PSME3IP1 HJURP HJURP SIN3A SIN3A WFIKKN2 WFIKKN2 DACT1 DACT1 SORL1 SORL1 ENSCHIP00000023367 ENSCHIP00000023367 ENSCHIP00000023383 ENSCHIP00000023383 BMP4 BMP4 MYOCD MYOCD HIPK2 HIPK2 GCG GCG ENSCHIP00000023905 ENSCHIP00000023905 HEY1 HEY1 ANKRD33B ANKRD33B IFIT1 IFIT1 ABL1 ABL1 LRRK2 LRRK2 RIPOR3 RIPOR3 APOE APOE USP9X USP9X PARK7 PARK7 MAPRE3 MAPRE3 TGFBR1 TGFBR1 ARHGAP28 ARHGAP28 ISL1 ISL1 PEX14 PEX14 EIF3D EIF3D GTF2F1 GTF2F1 ENSCHIP00000008932 ENSCHIP00000008932 TGFB1 TGFB1 DDIT3 DDIT3 PLN PLN ZC4H2 ZC4H2 TTBK1 TTBK1 SKI SKI SPTA1 SPTA1 ERCC4 ERCC4 ZBTB7A ZBTB7A PLK1 PLK1 CTSZ CTSZ ZNF593 ZNF593 PHLDA2 PHLDA2 MITD1 MITD1 AKTIP AKTIP MAD2L2 MAD2L2 STK3 STK3 WFIKKN1 WFIKKN1 HFE HFE STING1 STING1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CFHR5Complement factor H related 5. (571 aa)
ZFPM1Zinc finger protein, FOG family member 1. (988 aa)
PLCL2Phosphoinositide phospholipase C. (1118 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1607 aa)
GEMIN2Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (269 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
TCF7L2Transcription factor 7 like 2. (669 aa)
DAB2DAB adaptor protein 2. (768 aa)
NEK2NIMA related kinase 2. (445 aa)
ZFP90ZFP90 zinc finger protein. (652 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
DDRGK1DDRGK domain containing 1. (298 aa)
ENSCHIP00000005210Uncharacterized protein. (237 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (873 aa)
GATA1GATA binding protein 1. (413 aa)
ZNF462Zinc finger protein 462. (2502 aa)
LRRC6Leucine rich repeat containing 6. (474 aa)
PLXND1Plexin D1. (1926 aa)
MFNGBeta-1,3-N-acetylglucosaminyltransferase. (320 aa)
MEPCEMethylphosphate capping enzyme. (687 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
NIBAN2Niban apoptosis regulator 2. (744 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1123 aa)
MED25Mediator complex subunit 25. (744 aa)
BTAF1B-TFIID TATA-box binding protein associated factor 1. (1848 aa)
RIPOR2Uncharacterized protein. (1052 aa)
GZMAGranzyme A; Belongs to the peptidase S1 family. (259 aa)
SPAG8Uncharacterized protein. (368 aa)
ENSCHIP00000003109WD_REPEATS_REGION domain-containing protein. (59 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (258 aa)
CDONCell adhesion associated, oncogene regulated. (1254 aa)
DZIP1DAZ interacting zinc finger protein 1. (869 aa)
LOC106502849Uncharacterized protein. (242 aa)
SRCTyrosine-protein kinase. (538 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (161 aa)
ADAM15ADAM metallopeptidase domain 15. (866 aa)
EIF3EEukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (445 aa)
RTL8CDUF4939 domain-containing protein. (113 aa)
ENSCHIP00000019700DUF4939 domain-containing protein. (113 aa)
MARK3Non-specific serine/threonine protein kinase. (779 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (537 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1034 aa)
CKMT1AUncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (416 aa)
HABP4Hyaluronan binding protein 4. (417 aa)
PLAURPlasminogen activator, urokinase receptor. (331 aa)
CAMK1Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. (370 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
S100A10S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa)
ENSCHIP00000018388Uncharacterized protein. (57 aa)
EP300E1A binding protein p300. (2411 aa)
NME1Nucleoside diphosphate kinase. (157 aa)
ZNF304Zinc finger protein 304. (662 aa)
CRMP1Collapsin response mediator protein 1. (584 aa)
TFIP11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (837 aa)
IRF4Interferon regulatory factor 4. (450 aa)
ENSCHIP00000017024PID domain-containing protein. (190 aa)
IFIT2Interferon induced protein with tetratricopeptide repeats 2. (462 aa)
USP33Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (906 aa)
DNAJB2DnaJ heat shock protein family (Hsp40) member B2. (325 aa)
MMP9Uncharacterized protein. (709 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1142 aa)
BAG2BCL2 associated athanogene 2. (211 aa)
IDEInsulin degrading enzyme; Belongs to the peptidase M16 family. (1019 aa)
CLIC2Chloride intracellular channel 2. (247 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (166 aa)
ADD2Adducin 2. (715 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
ANKRD33ANK_REP_REGION domain-containing protein. (268 aa)
PARK2Ubiquitin-like domain-containing protein. (293 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4303 aa)
BCL3BCL3 transcription coactivator. (454 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (855 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
ENSCHIP00000015495Uncharacterized protein. (211 aa)
NMD360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (503 aa)
ARRB2Arrestin beta 2. (420 aa)
SUMO3Small ubiquitin-related modifier. (104 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (573 aa)
NPHP3TPR_REGION domain-containing protein. (1325 aa)
NUCKS1Uncharacterized protein. (248 aa)
E2F1E2F transcription factor 1. (441 aa)
RACK1Receptor for activated C kinase 1. (317 aa)
FBXW7F-box and WD repeat domain containing 7. (705 aa)
NFATC4Nuclear factor of activated T cells 4. (901 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
KRIT1Uncharacterized protein. (736 aa)
ZNF618Zinc finger protein 618. (909 aa)
EBF2EBF transcription factor 2. (575 aa)
DTX3LDeltex E3 ubiquitin ligase 3L. (738 aa)
TMC8Transmembrane channel-like protein. (715 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
LOC102189480Uncharacterized protein; Belongs to the universal ribosomal protein uL5 family. (163 aa)
PAX6Paired box 6. (486 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (495 aa)
BLKTyrosine-protein kinase. (501 aa)
MAPRE1Microtubule associated protein RP/EB family member 1. (268 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (780 aa)
LFNGBeta-1,3-N-acetylglucosaminyltransferase. (380 aa)
ENSCHIP00000026982Uncharacterized protein; Belongs to the universal ribosomal protein uL5 family. (173 aa)
DTNBP1Dystrobrevin binding protein 1. (297 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
LOC102180576Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
CLN5Uncharacterized protein. (359 aa)
CBLBCbl proto-oncogene B. (983 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (405 aa)
TRIM21Tripartite motif containing 21. (465 aa)
LRP1LDL receptor related protein 1. (4442 aa)
SPON1Spondin 1. (807 aa)
LHX2Uncharacterized protein. (422 aa)
NSD1Nuclear receptor binding SET domain protein 1. (2698 aa)
SPPL3Signal peptide peptidase like 3. (384 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
CCPG1Cell cycle progression 1. (810 aa)
TTBK2Tau tubulin kinase 2. (1244 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (483 aa)
RSF1Remodeling and spacing factor 1. (1429 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1384 aa)
EPHA4EPH receptor A4. (986 aa)
GATA3GATA binding protein 3. (467 aa)
HIP1RHuntingtin interacting protein 1 related. (1115 aa)
ENSCHIP00000030535zf-RING_14 domain-containing protein. (149 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (475 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1026 aa)
LEF1HMG box domain-containing protein. (430 aa)
ACDACD shelterin complex subunit and telomerase recruitment factor. (458 aa)
CTNNB1Catenin beta 1. (781 aa)
TTC36Tetratricopeptide repeat domain 36. (188 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1675 aa)
STYXSerine/threonine/tyrosine interacting protein. (223 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
RFNGBeta-1,3-N-acetylglucosaminyltransferase. (336 aa)
GTF2BGeneral transcription factor IIB. (316 aa)
TEX14Testis expressed 14, intercellular bridge forming factor. (1479 aa)
ARHGEF7Uncharacterized protein. (845 aa)
CPNE1Copine 1. (537 aa)
NESNestin; Belongs to the intermediate filament family. (1606 aa)
PINX1PIN2 (TERF1) interacting telomerase inhibitor 1. (312 aa)
APPAmyloid beta precursor protein. (770 aa)
ADIPOQC1q domain-containing protein. (283 aa)
PPP3CASerine/threonine-protein phosphatase. (527 aa)
SYMPKSymplekin. (1272 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
MMP8Matrix metallopeptidase 8. (470 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (649 aa)
ENSCHIP00000033427Uncharacterized protein. (262 aa)
FBXW9F-box and WD repeat domain containing 9. (458 aa)
HOPXHomeobox domain-containing protein. (73 aa)
RB1RB transcriptional corepressor 1. (931 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (335 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (310 aa)
POU4F1POU domain protein. (421 aa)
STK4Serine/threonine kinase 4. (487 aa)
HAND1Heart and neural crest derivatives expressed 1. (219 aa)
C6H4orf3Uncharacterized protein. (69 aa)
ZBTB7CZinc finger and BTB domain containing 7C. (660 aa)
NVLNuclear VCP like. (860 aa)
ENSCHIP00000000967SH3 domain-containing protein. (527 aa)
TMBIM6Transmembrane BAX inhibitor motif containing 6; Belongs to the BI1 family. (236 aa)
ENSCHIP00000000419DUSP domain-containing protein. (91 aa)
FMR1Fragile X mental retardation 1. (632 aa)
EDF1Endothelial differentiation related factor 1. (148 aa)
DOT1LHistone-lysine N-methyltransferase, H3 lysine-79 specific. (1713 aa)
SRISorcin. (198 aa)
EPHB6EPH receptor B6. (1011 aa)
TRIM6Tripartite motif containing 6. (487 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
DVL1Dishevelled segment polarity protein 1. (682 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (316 aa)
CSF3Colony stimulating factor 3. (226 aa)
PTPRFProtein tyrosine phosphatase receptor type F. (1902 aa)
RARARetinoic acid receptor alpha. (462 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
VTNSMB domain-containing protein. (475 aa)
EPB41Erythrocyte membrane protein band 4.1. (860 aa)
TFAP4Transcription factor AP-4. (335 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
AMFRAutocrine motility factor receptor. (630 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
EPB41L5FERM domain-containing protein. (505 aa)
MSX1Msh homeobox 1. (303 aa)
CDC42Uncharacterized protein. (191 aa)
PABPN1LPoly(A) binding protein nuclear 1 like, cytoplasmic. (307 aa)
LOC108634550USP domain-containing protein; Belongs to the peptidase C19 family. (2572 aa)
HMGA2Uncharacterized protein. (104 aa)
AGERAdvanced glycosylation end-product specific receptor. (416 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
WAPLWAPL cohesin release factor. (1193 aa)
LARP6La ribonucleoprotein domain family member 6. (492 aa)
MEN1Menin 1. (609 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
PEX19Uncharacterized protein. (299 aa)
ACTBUncharacterized protein. (375 aa)
PLCL1Phosphoinositide phospholipase C. (1055 aa)
LOC102184761Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (260 aa)
EFHBEF-hand domain family member B. (837 aa)
BMP2TGF_BETA_2 domain-containing protein. (381 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (163 aa)
PON1Paraoxonase 1. (357 aa)
CTHRC1Collagen triple helix repeat containing 1. (243 aa)
DHRS7BDehydrogenase/reductase 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (327 aa)
DHX9DExH-box helicase 9. (1271 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
LOC108634461Protein FAM127. (113 aa)
LOC102185270Protein FAM127. (113 aa)
IGF1Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (188 aa)
DERL1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa)
RALBRAS like proto-oncogene B. (206 aa)
SMAD4Mothers against decapentaplegic homolog. (513 aa)
LDOC1LDOC1 regulator of NFKB signaling. (145 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
ILRUNInflammation and lipid regulator with UBA-like and NBR1-like domains. (291 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1033 aa)
RNF220RING-type domain-containing protein. (388 aa)
GMNNGeminin DNA replication inhibitor. (186 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (390 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (199 aa)
ENSCHIP00000021995Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (239 aa)
NCBP1Nuclear cap binding protein subunit 1. (795 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
CTBP2Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (459 aa)
PBXIP1PBX homeobox interacting protein 1. (726 aa)
LRPAP1LDL receptor related protein associated protein 1. (303 aa)
CDT1Chromatin licensing and DNA replication factor 1. (637 aa)
TRIM28Tripartite motif containing 28. (837 aa)
ENSCHIP000000096742-Hacid_dh domain-containing protein. (402 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
XIRP1Xin actin binding repeat containing 1. (1823 aa)
TRIB3Tribbles pseudokinase 3. (357 aa)
MDFIMyoD family inhibitor. (247 aa)
RPL11Uncharacterized protein; Belongs to the universal ribosomal protein uL5 family. (178 aa)
PSME3IP1Family with sequence similarity 192 member A. (251 aa)
HJURPHolliday junction recognition protein. (694 aa)
SIN3ASIN3 transcription regulator family member A. (1274 aa)
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (574 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (831 aa)
SORL1Sortilin related receptor 1. (2211 aa)
ENSCHIP00000023367Calponin-homology (CH) domain-containing protein. (228 aa)
ENSCHIP00000023383RBR-type E3 ubiquitin transferase. (84 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
MYOCDMyocardin. (982 aa)
HIPK2Homeodomain interacting protein kinase 2. (1228 aa)
GCGGlucagon. (180 aa)
ENSCHIP00000023905Uncharacterized protein. (90 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
ANKRD33BAnkyrin repeat domain 33B. (488 aa)
IFIT1Interferon induced protein with tetratricopeptide repeats 1. (481 aa)
ABL1Tyrosine-protein kinase. (1151 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
RIPOR3RIPOR family member 3. (947 aa)
APOEApolipoprotein E. (326 aa)
USP9XUbiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2570 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
MAPRE3Microtubule associated protein RP/EB family member 3. (281 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
ARHGAP28Rho GTPase activating protein 28. (648 aa)
ISL1ISL LIM homeobox 1. (349 aa)
PEX14Peroxisomal biogenesis factor 14. (365 aa)
EIF3DEukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...] (548 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (546 aa)
ENSCHIP00000008932Uncharacterized protein. (166 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
ZC4H2Zinc finger C4H2-type containing. (222 aa)
TTBK1Tau tubulin kinase 1. (1311 aa)
SKISKI proto-oncogene. (729 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2402 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (602 aa)
PLK1Serine/threonine-protein kinase PLK. (602 aa)
CTSZCathepsin Z; Belongs to the peptidase C1 family. (304 aa)
ZNF593Zinc finger protein 593. (134 aa)
PHLDA2Pleckstrin homology like domain family A member 2. (128 aa)
MITD1Microtubule interacting and trafficking domain containing 1. (249 aa)
AKTIPAKT interacting protein. (293 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (195 aa)
STK3Serine/threonine kinase 3. (495 aa)
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (550 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (356 aa)
STING1Transmembrane protein 173. (378 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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