(30 nodes) Positive regulation of striated muscle cell differentiation network (Capra hircus)

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Your Input:
	ATP11A	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1146 aa)
	HOPX	Homeobox domain-containing protein. (73 aa)
	MESP1	Mesoderm posterior bHLH transcription factor 1. (256 aa)
	TRIM32	Tripartite motif containing 32. (695 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	MMP14	ZnMc domain-containing protein. (584 aa)
	EDN1	Endothelin 1. (202 aa)
	RBM24	RNA binding motif protein 24. (248 aa)
	ACTN3	Actinin alpha 3 (gene/pseudogene). (902 aa)
	MYF5	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (260 aa)
	ARRB2	Arrestin beta 2. (420 aa)
	SHOX2	Short stature homeobox 2. (319 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
	MEF2C	MADS-box domain-containing protein. (441 aa)
	BCL2	BH4_2 domain-containing protein. (229 aa)
	SMYD1	SET and MYND domain containing 1. (494 aa)
	CYP26B1	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
	NEK5	NIMA related kinase 5. (715 aa)
	LMOD3	Leiomodin 3. (567 aa)
	MAMSTR	MEF2 activating motif and SAP domain containing transcriptional regulator. (416 aa)
	IGF1	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (188 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	MYOCD	Myocardin. (982 aa)
	MYOG	Myogenin. (224 aa)
	PROX1	Prospero homeobox 1. (734 aa)
	MYF6	BHLH domain-containing protein. (242 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
	MAML1	Mastermind like transcriptional coactivator 1. (1018 aa)
	BMP10	Bone morphogenetic protein 10. (424 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN3	MYF5	ENSCHIP00000011760	ENSCHIP00000013733	Actinin alpha 3 (gene/pseudogene).	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.401
ACTN3	MYF6	ENSCHIP00000011760	ENSCHIP00000024510	Actinin alpha 3 (gene/pseudogene).	BHLH domain-containing protein.	0.668
ACTN3	SMYD1	ENSCHIP00000011760	ENSCHIP00000016911	Actinin alpha 3 (gene/pseudogene).	SET and MYND domain containing 1.	0.426
BCL2	IGF1	ENSCHIP00000015831	ENSCHIP00000020185	BH4_2 domain-containing protein.	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	0.730
BCL2	MTOR	ENSCHIP00000015831	ENSCHIP00000021872	BH4_2 domain-containing protein.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.680
BCL2	SHH	ENSCHIP00000015831	ENSCHIP00000027767	BH4_2 domain-containing protein.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.490
BCL2	WNT3A	ENSCHIP00000015831	ENSCHIP00000015590	BH4_2 domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.439
BMP10	BMP4	ENSCHIP00000031863	ENSCHIP00000023678	Bone morphogenetic protein 10.	Bone morphogenetic protein 4.	0.665
BMP4	BMP10	ENSCHIP00000023678	ENSCHIP00000031863	Bone morphogenetic protein 4.	Bone morphogenetic protein 10.	0.665
BMP4	EDN1	ENSCHIP00000023678	ENSCHIP00000008821	Bone morphogenetic protein 4.	Endothelin 1.	0.487
BMP4	IGF1	ENSCHIP00000023678	ENSCHIP00000020185	Bone morphogenetic protein 4.	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	0.667
BMP4	MEF2C	ENSCHIP00000023678	ENSCHIP00000015775	Bone morphogenetic protein 4.	MADS-box domain-containing protein.	0.577
BMP4	MYF5	ENSCHIP00000023678	ENSCHIP00000013733	Bone morphogenetic protein 4.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.445
BMP4	SHH	ENSCHIP00000023678	ENSCHIP00000027767	Bone morphogenetic protein 4.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.909
BMP4	SHOX2	ENSCHIP00000023678	ENSCHIP00000015506	Bone morphogenetic protein 4.	Short stature homeobox 2.	0.525
BMP4	WNT3A	ENSCHIP00000023678	ENSCHIP00000015590	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.874
CAV3	MYOG	ENSCHIP00000006073	ENSCHIP00000023943	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Myogenin.	0.664
EDN1	BMP4	ENSCHIP00000008821	ENSCHIP00000023678	Endothelin 1.	Bone morphogenetic protein 4.	0.487
EDN1	IGF1	ENSCHIP00000008821	ENSCHIP00000020185	Endothelin 1.	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	0.541
IGF1	BCL2	ENSCHIP00000020185	ENSCHIP00000015831	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	BH4_2 domain-containing protein.	0.730