STRINGSTRING
HADHA HADHA ME1 ME1 NDUFV1 NDUFV1 UXS1 UXS1 ALDH2 ALDH2 GLYR1 GLYR1 NDUFS2 NDUFS2 HPGD HPGD UGDH UGDH ENSCHIP00000030302 ENSCHIP00000030302 CTBP1 CTBP1 LOC108636856 LOC108636856 LOC102176872 LOC102176872 SIRT6 SIRT6 AHCY AHCY ENSCHIP00000032066 ENSCHIP00000032066 SIRT4 SIRT4 ME2 ME2 IDH2 IDH2 ENSCHIP00000003272 ENSCHIP00000003272 ENSCHIP00000003651 ENSCHIP00000003651 LOC102176799 LOC102176799 GAPDHS GAPDHS EHHADH EHHADH QDPR QDPR SIRT1 SIRT1 HIBADH HIBADH NUDT6 NUDT6 IDH3B IDH3B GPD1L GPD1L ENSCHIP00000008372 ENSCHIP00000008372 ENSCHIP00000009167 ENSCHIP00000009167 LOC102173738 LOC102173738 ENSCHIP00000009674 ENSCHIP00000009674 LOC102181016 LOC102181016 AOX1 AOX1 HADH HADH LOC102171556 LOC102171556 IDH3A IDH3A ME3 ME3 SIRT3 SIRT3 LOC102184018 LOC102184018 B3GAT3 B3GAT3 ENSCHIP00000016404 ENSCHIP00000016404 SIRT7 SIRT7 IDH3G IDH3G SIRT5 SIRT5 B3GAT1 B3GAT1 RNLS RNLS HSD17B8 HSD17B8 ALDH1A1 ALDH1A1 PARP1 PARP1 ENSCHIP00000019185 ENSCHIP00000019185 IDH1 IDH1 PARP14 PARP14 PHGDH PHGDH B3GAT2 B3GAT2 ENSCHIP00000020279 ENSCHIP00000020279 BDH2 BDH2 GRHPR GRHPR SIRT2 SIRT2 CRYL1 CRYL1 CTBP2 CTBP2 GPD1 GPD1 ENSCHIP00000022264 ENSCHIP00000022264 ENSCHIP00000022456 ENSCHIP00000022456 LOC102188176 LOC102188176 ALDH1A3 ALDH1A3 SORD SORD LOC102190753 LOC102190753 NNT NNT GAPDH GAPDH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)
ME1Malic enzyme. (571 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa)
UXS1Uncharacterized protein. (420 aa)
ALDH2Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (524 aa)
GLYR1Glyoxylate reductase 1 homolog. (553 aa)
NDUFS2NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (463 aa)
HPGD15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)
UGDHUDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (494 aa)
ENSCHIP00000030302NAD_binding_11 domain-containing protein. (291 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (445 aa)
LOC108636856Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (301 aa)
LOC102176872PKS_ER domain-containing protein. (380 aa)
SIRT6Sirtuin 6. (335 aa)
AHCYAdenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. (432 aa)
ENSCHIP00000032066Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (308 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (315 aa)
ME2Malic enzyme. (584 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
ENSCHIP00000003272Uncharacterized protein. (336 aa)
ENSCHIP000000036513HCDH_N domain-containing protein. (259 aa)
LOC102176799Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase. (385 aa)
EHHADHEnoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase. (723 aa)
QDPRQuinoid dihydropteridine reductase. (242 aa)
SIRT1Deacetylase sirtuin-type domain-containing protein. (732 aa)
HIBADHUncharacterized protein. (336 aa)
NUDT6Nudix hydrolase 6; Belongs to the Nudix hydrolase family. (316 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (385 aa)
GPD1LGlycerol-3-phosphate dehydrogenase [NAD(+)]. (351 aa)
ENSCHIP00000008372Glycerol-3-phosphate dehydrogenase [NAD(+)]. (351 aa)
ENSCHIP00000009167Gp_dh_C domain-containing protein. (135 aa)
LOC102173738Uncharacterized protein. (392 aa)
ENSCHIP000000096742-Hacid_dh domain-containing protein. (402 aa)
LOC102181016Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (318 aa)
AOX1Aldehyde oxidase 1. (1339 aa)
HADHUncharacterized protein. (314 aa)
LOC102171556Uncharacterized protein. (1318 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
ME3Malic enzyme. (604 aa)
SIRT3NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (333 aa)
LOC102184018Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (328 aa)
B3GAT3Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (335 aa)
ENSCHIP00000016404Uncharacterized protein. (143 aa)
SIRT7Sirtuin 7. (405 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (388 aa)
SIRT5NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] (310 aa)
B3GAT1Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (383 aa)
RNLSAmino_oxidase domain-containing protein. (180 aa)
HSD17B8Hydroxysteroid 17-beta dehydrogenase 8. (259 aa)
ALDH1A1Aldehyde dehydrogenase 1 family member A1; Belongs to the aldehyde dehydrogenase family. (501 aa)
PARP1Poly [ADP-ribose] polymerase. (1020 aa)
ENSCHIP00000019185Gp_dh_N domain-containing protein. (273 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
PARP14Poly [ADP-ribose] polymerase. (1795 aa)
PHGDHD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
B3GAT2Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (326 aa)
ENSCHIP00000020279Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (353 aa)
BDH23-hydroxybutyrate dehydrogenase 2. (245 aa)
GRHPRGlyoxylate and hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (328 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (390 aa)
CRYL1Crystallin lambda 1. (321 aa)
CTBP2Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (459 aa)
GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)]. (358 aa)
ENSCHIP00000022264Uncharacterized protein. (365 aa)
ENSCHIP00000022456Uncharacterized protein. (174 aa)
LOC102188176FAD-binding PCMH-type domain-containing protein. (1339 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
SORDSorbitol dehydrogenase. (356 aa)
LOC102190753Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (305 aa)
NNTNicotinamide nucleotide transhydrogenase. (1086 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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