48 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NEBL	Nebulette. (662 aa)
	ENSCHIP00000002011	Formin_GBD_N domain-containing protein. (88 aa)
	ACTC1	Actin alpha cardiac muscle 1. (377 aa)
	LRRC10	Leucine rich repeat containing 10. (279 aa)
	HNRNPU	Heterogeneous nuclear ribonucleoprotein U. (806 aa)
	PDGFRA	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1108 aa)
	BVES	Blood vessel epicardial substance. (360 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	TCAP	Uncharacterized protein. (167 aa)
	LRRC10B	Leucine rich repeat containing 10B. (292 aa)
	BMPR1A	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
	ADPRHL1	ADP-ribosylhydrolase like 1. (354 aa)
	MYO18B	Myosin XVIIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2518 aa)
	TBX5	T-box transcription factor 5. (594 aa)
	ADPRH	ADP-ribosylarginine hydrolase. (354 aa)
	ALPK2	Alpha kinase 2. (2148 aa)
	MEF2A	MADS-box domain-containing protein. (500 aa)
	MAML1	Mastermind like transcriptional coactivator 1. (1018 aa)
	FHL2	Four and a half LIM domains 2. (279 aa)
	BMP10	Bone morphogenetic protein 10. (424 aa)
	HEY2	Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
	NKX2-6	NK2 homeobox 6. (300 aa)
	NEBL-2	Uncharacterized protein. (270 aa)
	CSRP3	Cysteine and glycine rich protein 3. (194 aa)
	LMNA	Lamin A/C; Belongs to the intermediate filament family. (665 aa)
	CXADR	Uncharacterized protein. (416 aa)
	ISL1	ISL LIM homeobox 1. (349 aa)
	PLEC	Plectin. (4150 aa)
	FHOD3	Formin homology 2 domain containing 3. (1541 aa)
	PROX1	Prospero homeobox 1. (734 aa)
	ADRA1A	Adrenoceptor alpha 1A. (466 aa)
	NRAP	Nebulin related anchoring protein. (1730 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	MYLK3	Myosin light chain kinase 3. (786 aa)
	SGCD	Sarcoglycan delta. (289 aa)
	ACTN2	Actinin alpha 2. (902 aa)
	ASB2	Ankyrin repeat and SOCS box containing 2. (633 aa)
	MYH11	Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1972 aa)
	TBX18	T-box transcription factor 18. (612 aa)
	SRF	Serum response factor. (509 aa)
	TBX3	T-box transcription factor 3. (749 aa)
	ENSCHIP00000009957	Calponin-homology (CH) domain-containing protein. (123 aa)
	ZMPSTE24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
	NEB	Nebulin. (6655 aa)
	ALPK3	Alpha kinase 3. (1840 aa)
	SHOX2	Short stature homeobox 2. (319 aa)
	MYH6	Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1943 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTC1	ACTN2	ENSCHIP00000002085	ENSCHIP00000006208	Actin alpha cardiac muscle 1.	Actinin alpha 2.	0.861
ACTC1	MYH11	ENSCHIP00000002085	ENSCHIP00000007181	Actin alpha cardiac muscle 1.	Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.736
ACTC1	MYH6	ENSCHIP00000002085	ENSCHIP00000017471	Actin alpha cardiac muscle 1.	Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.999
ACTC1	TBX5	ENSCHIP00000002085	ENSCHIP00000028388	Actin alpha cardiac muscle 1.	T-box transcription factor 5.	0.674
ACTN2	ACTC1	ENSCHIP00000006208	ENSCHIP00000002085	Actinin alpha 2.	Actin alpha cardiac muscle 1.	0.861
ACTN2	CAV3	ENSCHIP00000006208	ENSCHIP00000006073	Actinin alpha 2.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.459
ACTN2	CSRP3	ENSCHIP00000006208	ENSCHIP00000026803	Actinin alpha 2.	Cysteine and glycine rich protein 3.	0.794
ACTN2	LMNA	ENSCHIP00000006208	ENSCHIP00000026441	Actinin alpha 2.	Lamin A/C; Belongs to the intermediate filament family.	0.400
ACTN2	MYH11	ENSCHIP00000006208	ENSCHIP00000007181	Actinin alpha 2.	Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.584
ACTN2	MYH6	ENSCHIP00000006208	ENSCHIP00000017471	Actinin alpha 2.	Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.870
ACTN2	MYLK3	ENSCHIP00000006208	ENSCHIP00000021129	Actinin alpha 2.	Myosin light chain kinase 3.	0.600
ACTN2	MYO18B	ENSCHIP00000006208	ENSCHIP00000027756	Actinin alpha 2.	Myosin XVIIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.481
ACTN2	NEB	ENSCHIP00000006208	ENSCHIP00000012713	Actinin alpha 2.	Nebulin.	0.659
ACTN2	NEBL	ENSCHIP00000006208	ENSCHIP00000028095	Actinin alpha 2.	Nebulette.	0.719
ACTN2	NEBL-2	ENSCHIP00000006208	ENSCHIP00000027141	Actinin alpha 2.	Uncharacterized protein.	0.719
ACTN2	NRAP	ENSCHIP00000006208	ENSCHIP00000022079	Actinin alpha 2.	Nebulin related anchoring protein.	0.473
ACTN2	TBX5	ENSCHIP00000006208	ENSCHIP00000028388	Actinin alpha 2.	T-box transcription factor 5.	0.671
ACTN2	TCAP	ENSCHIP00000006208	ENSCHIP00000001814	Actinin alpha 2.	Uncharacterized protein.	0.829
ATG5	MTOR	ENSCHIP00000021333	ENSCHIP00000021872	Autophagy protein 5; Involved in autophagic vesicle formation.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.768
BMP10	BMPR1A	ENSCHIP00000031863	ENSCHIP00000000640	Bone morphogenetic protein 10.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.621