STRINGSTRING
KCNH2 KCNH2 RYR2 RYR2 ABCC9 ABCC9 SNTA1 SNTA1 SCN1B SCN1B SCN2B SCN2B EXT2 EXT2 PPP1R13L PPP1R13L SCN1A SCN1A RANGRF RANGRF MYL10 MYL10 TRDN TRDN VEGFB VEGFB MAP2K6 MAP2K6 DNM1L DNM1L ATP1B1 ATP1B1 KCNJ8 KCNJ8 CACNA2D1 CACNA2D1 CSRP3 CSRP3 GRK2 GRK2 MYL7 MYL7 MYH7 MYH7 GSN GSN KCNQ1 KCNQ1 TNNT2 TNNT2 TNNI3 TNNI3 MTOR MTOR ATG5 ATG5 CACNA1D CACNA1D KCND3 KCND3 SGCD SGCD TNNC1 TNNC1 GATA6 GATA6 KCNE5 KCNE5 ATP1A1 ATP1A1 NKX2-5 NKX2-5 MYH6 MYH6 NUP155 NUP155 TNNI1 TNNI1 GAA GAA PIK3CA PIK3CA SCN5A SCN5A CACNA1C CACNA1C MYL4 MYL4 SMAD5 SMAD5 PKP2 PKP2 SOD1 SOD1 CASQ2 CASQ2 MAP2K3 MAP2K3 CDC42 CDC42 MYL3 MYL3 KCNJ5 KCNJ5 KCNE1 KCNE1 SGCZ SGCZ SCN4B SCN4B SGCG SGCG KCNE4 KCNE4 EXT1 EXT1 KCNE2 KCNE2 SCN3B SCN3B KCNN2 KCNN2 ACTC1 ACTC1 KCNE3 KCNE3 TNNI2 TNNI2 TCAP TCAP KCNJ2 KCNJ2 CACNB2 CACNB2 KCNA5 KCNA5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KCNH2Potassium voltage-gated channel subfamily H member 2. (1145 aa)
RYR2Ryanodine receptor 2. (4943 aa)
ABCC9ATP binding cassette subfamily C member 9. (1549 aa)
SNTA1Syntrophin alpha 1. (505 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (219 aa)
SCN2BSodium voltage-gated channel beta subunit 2. (215 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (737 aa)
PPP1R13LProtein phosphatase 1 regulatory subunit 13 like. (823 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2002 aa)
RANGRFRAN guanine nucleotide release factor. (186 aa)
MYL10Myosin light chain 10. (222 aa)
TRDNAsp-B-Hydro_N domain-containing protein. (144 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (197 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (344 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (707 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
KCNJ8Potassium voltage-gated channel subfamily J member 8. (424 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1098 aa)
CSRP3Cysteine and glycine rich protein 3. (194 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (694 aa)
MYL7Myosin light chain 7. (175 aa)
MYH7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1955 aa)
GSNGelsolin. (785 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (670 aa)
TNNT2Troponin T2, cardiac type. (267 aa)
TNNI3Uncharacterized protein. (228 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2110 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (655 aa)
SGCDSarcoglycan delta. (289 aa)
TNNC1Uncharacterized protein. (154 aa)
GATA6GATA binding protein 6. (592 aa)
KCNE5Potassium voltage-gated channel subfamily E regulatory subunit 5. (145 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1028 aa)
NKX2-5NK2 homeobox 5. (323 aa)
MYH6Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1943 aa)
NUP155Nucleoporin 155. (1391 aa)
TNNI1Troponin I1, slow skeletal type. (187 aa)
GAAGlucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family. (935 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2020 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2092 aa)
MYL4Myosin light chain 4. (193 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
PKP2Plakophilin 2. (851 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (430 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (349 aa)
CDC42Uncharacterized protein. (191 aa)
MYL3Myosin light chain 3. (194 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
KCNE1Uncharacterized protein. (129 aa)
SGCZSarcoglycan zeta. (264 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (229 aa)
SGCGSarcoglycan gamma. (291 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (168 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (446 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
SCN3BSodium voltage-gated channel beta subunit 3. (224 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (852 aa)
ACTC1Actin alpha cardiac muscle 1. (377 aa)
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (99 aa)
TNNI2Troponin I2, fast skeletal type. (170 aa)
TCAPUncharacterized protein. (167 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (613 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (598 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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