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KCNA5 KCNA5 CACNB2 CACNB2 KCNJ2 KCNJ2 TCAP TCAP TNNI2 TNNI2 KCNE3 KCNE3 KCNN2 KCNN2 SCN3B SCN3B KCNE2 KCNE2 KCNE4 KCNE4 SCN4B SCN4B KCNE1 KCNE1 KCNJ5 KCNJ5 MYL3 MYL3 MAP2K3 MAP2K3 CASQ2 CASQ2 PKP2 PKP2 SMAD5 SMAD5 MYL4 MYL4 CACNA1C CACNA1C SCN5A SCN5A PIK3CA PIK3CA GAA GAA TNNI1 TNNI1 NUP155 NUP155 MYH6 MYH6 NKX2-5 NKX2-5 KCNE5 KCNE5 KCNH2 KCNH2 TNNC1 TNNC1 SGCD SGCD KCND3 KCND3 CACNA1D CACNA1D MTOR MTOR TNNI3 TNNI3 TNNT2 TNNT2 KCNQ1 KCNQ1 GSN GSN MYH7 MYH7 GRK2 GRK2 CSRP3 CSRP3 CACNA2D1 CACNA2D1 KCNJ8 KCNJ8 ATP1B1 ATP1B1 MAP2K6 MAP2K6 VEGFB VEGFB MYL10 MYL10 SCN1A SCN1A PPP1R13L PPP1R13L SCN2B SCN2B SCN1B SCN1B SNTA1 SNTA1 ABCC9 ABCC9 RYR2 RYR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (598 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (613 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
TCAPUncharacterized protein. (167 aa)
TNNI2Troponin I2, fast skeletal type. (170 aa)
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (99 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (852 aa)
SCN3BSodium voltage-gated channel beta subunit 3. (224 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (168 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (229 aa)
KCNE1Uncharacterized protein. (129 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
MYL3Myosin light chain 3. (194 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (349 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (430 aa)
PKP2Plakophilin 2. (851 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
MYL4Myosin light chain 4. (193 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2092 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2020 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
GAAGlucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family. (935 aa)
TNNI1Troponin I1, slow skeletal type. (187 aa)
NUP155Nucleoporin 155. (1391 aa)
MYH6Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1943 aa)
NKX2-5NK2 homeobox 5. (323 aa)
KCNE5Potassium voltage-gated channel subfamily E regulatory subunit 5. (145 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1145 aa)
TNNC1Uncharacterized protein. (154 aa)
SGCDSarcoglycan delta. (289 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (655 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2110 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
TNNI3Uncharacterized protein. (228 aa)
TNNT2Troponin T2, cardiac type. (267 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (670 aa)
GSNGelsolin. (785 aa)
MYH7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1955 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (694 aa)
CSRP3Cysteine and glycine rich protein 3. (194 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1098 aa)
KCNJ8Potassium voltage-gated channel subfamily J member 8. (424 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (344 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (197 aa)
MYL10Myosin light chain 10. (222 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2002 aa)
PPP1R13LProtein phosphatase 1 regulatory subunit 13 like. (823 aa)
SCN2BSodium voltage-gated channel beta subunit 2. (215 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (219 aa)
SNTA1Syntrophin alpha 1. (505 aa)
ABCC9ATP binding cassette subfamily C member 9. (1549 aa)
RYR2Ryanodine receptor 2. (4943 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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