20 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NPTX1	Neuronal pentraxin 1. (432 aa)
	LRIG1	Leucine rich repeats and immunoglobulin like domains 1. (1089 aa)
	EDN1	Endothelin 1. (202 aa)
	POU4F1	POU domain protein. (421 aa)
	NTF4	Neurotrophin 4; Belongs to the NGF-beta family. (210 aa)
	RNF165	Ring finger protein 165. (347 aa)
	CHD7	Chromodomain helicase DNA binding protein 7. (2993 aa)
	FBXO45	F-box protein 45. (281 aa)
	SULF1	Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (868 aa)
	GABRB2	Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
	ECE1	Endothelin converting enzyme 1. (767 aa)
	GABRA5	Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
	NTRK1	Tyrosine-protein kinase receptor. (821 aa)
	ISL1	ISL LIM homeobox 1. (349 aa)
	LRIG2	Leucine rich repeats and immunoglobulin like domains 2. (1065 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	ADARB1	Adenosine deaminase RNA specific B1. (701 aa)
	SERPINE2	Serpin family E member 2; Belongs to the serpin family. (397 aa)
	COL25A1	Collagen type XXV alpha 1 chain. (391 aa)
	SULF2	Sulfatase 2. (864 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ECE1	EDN1	ENSCHIP00000028549	ENSCHIP00000008821	Endothelin converting enzyme 1.	Endothelin 1.	0.964
ECE1	EDNRA	ENSCHIP00000028549	ENSCHIP00000021413	Endothelin converting enzyme 1.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.667
EDN1	ECE1	ENSCHIP00000008821	ENSCHIP00000028549	Endothelin 1.	Endothelin converting enzyme 1.	0.964
EDN1	EDNRA	ENSCHIP00000008821	ENSCHIP00000021413	Endothelin 1.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.999
EDNRA	ECE1	ENSCHIP00000021413	ENSCHIP00000028549	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin converting enzyme 1.	0.667
EDNRA	EDN1	ENSCHIP00000021413	ENSCHIP00000008821	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.999
GABRA5	GABRB2	ENSCHIP00000028092	ENSCHIP00000029891	Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.772
GABRB2	GABRA5	ENSCHIP00000029891	ENSCHIP00000028092	Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.772
ISL1	POU4F1	ENSCHIP00000025978	ENSCHIP00000001764	ISL LIM homeobox 1.	POU domain protein.	0.811
LRIG1	LRIG2	ENSCHIP00000010082	ENSCHIP00000024061	Leucine rich repeats and immunoglobulin like domains 1.	Leucine rich repeats and immunoglobulin like domains 2.	0.493
LRIG2	LRIG1	ENSCHIP00000024061	ENSCHIP00000010082	Leucine rich repeats and immunoglobulin like domains 2.	Leucine rich repeats and immunoglobulin like domains 1.	0.493
NTF4	NTRK1	ENSCHIP00000005302	ENSCHIP00000027302	Neurotrophin 4; Belongs to the NGF-beta family.	Tyrosine-protein kinase receptor.	0.950
NTRK1	NTF4	ENSCHIP00000027302	ENSCHIP00000005302	Tyrosine-protein kinase receptor.	Neurotrophin 4; Belongs to the NGF-beta family.	0.950
POU4F1	ISL1	ENSCHIP00000001764	ENSCHIP00000025978	POU domain protein.	ISL LIM homeobox 1.	0.811