STRINGSTRING
NODAL NODAL LDLRAD4 LDLRAD4 BMPR1A BMPR1A GDF11 GDF11 TGFB3 TGFB3 NOG NOG DAB2 DAB2 BMP7 BMP7 GDF10 GDF10 BMP5 BMP5 HFE HFE LOC102183990 LOC102183990 GREM1 GREM1 GDF7 GDF7 TGFBR2 TGFBR2 GDF3 GDF3 TGFB1 TGFB1 GDF5 GDF5 SMAD6 SMAD6 PIN1 PIN1 BMP2 BMP2 ACVR2A ACVR2A CSNK2B CSNK2B LOC102183441 LOC102183441 LY6G5B LY6G5B INHBC INHBC SDCBP SDCBP GDF2 GDF2 BMPER BMPER SMAD4 SMAD4 SMAD7 SMAD7 GDF6 GDF6 PMEPA1 PMEPA1 EMILIN1 EMILIN1 BMPR2 BMPR2 BMP8A BMP8A BMP4 BMP4 TGFBR1 TGFBR1 INHBE INHBE TGFB2 TGFB2 INHBB INHBB BMP3 BMP3 BMP8B BMP8B INHBA INHBA BMP10 BMP10 TWSG1 TWSG1 BMP6 BMP6 GDF1 GDF1 ENG ENG ACVRL1 ACVRL1 GDF15 GDF15 RBPMS RBPMS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NODALNodal growth differentiation factor. (346 aa)
LDLRAD4Low density lipoprotein receptor class A domain containing 4. (289 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
GDF11Growth differentiation factor 11. (406 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (452 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
DAB2DAB adaptor protein 2. (768 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (478 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (356 aa)
LOC102183990Left-right determination factor. (367 aa)
GREM1Gremlin. (184 aa)
GDF7Growth differentiation factor 7. (451 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (550 aa)
GDF3Growth differentiation factor 3. (364 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
GDF5Growth differentiation factor 5. (499 aa)
SMAD6Mothers against decapentaplegic homolog. (497 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (163 aa)
BMP2TGF_BETA_2 domain-containing protein. (381 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (217 aa)
LOC102183441Left-right determination factor. (367 aa)
LY6G5BLymphocyte antigen 6 family member G5B. (196 aa)
INHBCInhibin subunit beta C. (352 aa)
SDCBPSyndecan binding protein. (359 aa)
GDF2Growth differentiation factor 2. (430 aa)
BMPERBMP binding endothelial regulator. (685 aa)
SMAD4Mothers against decapentaplegic homolog. (513 aa)
SMAD7Mothers against decapentaplegic homolog. (427 aa)
GDF6Growth differentiation factor 6. (463 aa)
PMEPA1Prostate transmembrane protein, androgen induced 1. (290 aa)
EMILIN1Elastin microfibril interfacer 1. (1017 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
BMP8ATGF_BETA_2 domain-containing protein. (405 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
INHBEInhibin subunit beta E. (348 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
INHBBInhibin subunit beta B. (408 aa)
BMP3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (467 aa)
BMP8BTGF_BETA_2 domain-containing protein. (405 aa)
INHBAInhibin beta A subunit. (425 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
BMP6Bone morphogenetic protein 6. (496 aa)
GDF1TGF_BETA_2 domain-containing protein. (368 aa)
ENGEndoglin. (649 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
GDF15Growth differentiation factor 15. (308 aa)
RBPMSRNA binding protein, mRNA processing factor. (197 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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