43 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RPL13A	Uncharacterized protein; Belongs to the universal ribosomal protein uL13 family. (203 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa)
	NODAL	Nodal growth differentiation factor. (346 aa)
	DLG5	Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1946 aa)
	HHIP	Hedgehog interacting protein. (701 aa)
	HOXA5	Homeobox A5. (270 aa)
	SPRY2	Sprouty RTK signaling antagonist 2. (315 aa)
	EXT1	Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (446 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	WNT2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
	CTSZ	Cathepsin Z; Belongs to the peptidase C1 family. (304 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (550 aa)
	SRF	Serum response factor. (509 aa)
	LOC108636572	Uncharacterized protein; Belongs to the universal ribosomal protein uL13 family. (197 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	LIF	LIF interleukin 6 family cytokine. (202 aa)
	TBX2	T-box transcription factor 2. (771 aa)
	PLOD3	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (751 aa)
	TCF21	Transcription factor 21. (179 aa)
	DAG1	Dystroglycan 1. (895 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
	RDH10	Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
	YAP1	Yes associated protein 1. (503 aa)
	GRHL2	Grainyhead like transcription factor 2. (622 aa)
	CELSR1	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2710 aa)
	SEC24B	SEC24 homolog B, COPII coat complex component. (1261 aa)
	AP3B1	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa)
	FOXF1	Forkhead box F1. (391 aa)
	ENSCHIP00000021691	Uncharacterized protein. (107 aa)
	ENSCHIP00000022448	Uncharacterized protein. (128 aa)
	STK40	Serine/threonine kinase 40. (436 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	MAP2K1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (397 aa)
	SOX9	SRY-box transcription factor 9. (525 aa)
	FOXA1	Forkhead box A1. (468 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
	NKX2-1	NK2 homeobox 1. (370 aa)
	ESRP2	Epithelial splicing regulatory protein 2. (717 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	CTSH	Cathepsin H; Belongs to the peptidase C1 family. (335 aa)
	KRAS	KRAS proto-oncogene, GTPase. (189 aa)
	LOC102175844	Uncharacterized protein. (204 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	CTNNB1	ENSCHIP00000023678	ENSCHIP00000031016	Bone morphogenetic protein 4.	Catenin beta 1.	0.800
BMP4	FGF10	ENSCHIP00000023678	ENSCHIP00000010028	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.887
BMP4	FGF8	ENSCHIP00000023678	ENSCHIP00000016903	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.763
BMP4	FOXA1	ENSCHIP00000023678	ENSCHIP00000027706	Bone morphogenetic protein 4.	Forkhead box A1.	0.426
BMP4	FOXF1	ENSCHIP00000023678	ENSCHIP00000020087	Bone morphogenetic protein 4.	Forkhead box F1.	0.621
BMP4	LIF	ENSCHIP00000023678	ENSCHIP00000012397	Bone morphogenetic protein 4.	LIF interleukin 6 family cytokine.	0.725
BMP4	NOG	ENSCHIP00000023678	ENSCHIP00000005264	Bone morphogenetic protein 4.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.999
BMP4	SHH	ENSCHIP00000023678	ENSCHIP00000027767	Bone morphogenetic protein 4.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.909
BMP4	SOX9	ENSCHIP00000023678	ENSCHIP00000024523	Bone morphogenetic protein 4.	SRY-box transcription factor 9.	0.769
BMP4	SPRY2	ENSCHIP00000023678	ENSCHIP00000004142	Bone morphogenetic protein 4.	Sprouty RTK signaling antagonist 2.	0.479
BMP4	TBX2	ENSCHIP00000023678	ENSCHIP00000012825	Bone morphogenetic protein 4.	T-box transcription factor 2.	0.542
BMP4	TGFBR2	ENSCHIP00000023678	ENSCHIP00000008226	Bone morphogenetic protein 4.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.657
BMP4	WNT2	ENSCHIP00000023678	ENSCHIP00000007601	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.465
CELSR1	SEC24B	ENSCHIP00000018726	ENSCHIP00000019232	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family.	SEC24 homolog B, COPII coat complex component.	0.605
CTNNB1	BMP4	ENSCHIP00000031016	ENSCHIP00000023678	Catenin beta 1.	Bone morphogenetic protein 4.	0.800
CTNNB1	DLG5	ENSCHIP00000031016	ENSCHIP00000000553	Catenin beta 1.	Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family.	0.614
CTNNB1	FGF10	ENSCHIP00000031016	ENSCHIP00000010028	Catenin beta 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.668
CTNNB1	FGF8	ENSCHIP00000031016	ENSCHIP00000016903	Catenin beta 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.608
CTNNB1	FOXA1	ENSCHIP00000031016	ENSCHIP00000027706	Catenin beta 1.	Forkhead box A1.	0.452
CTNNB1	FOXF1	ENSCHIP00000031016	ENSCHIP00000020087	Catenin beta 1.	Forkhead box F1.	0.420