STRINGSTRING
LOC108634563 LOC108634563 ENSCHIP00000000031 ENSCHIP00000000031 MAPK1 MAPK1 ENSCHIP00000000268 ENSCHIP00000000268 NODAL NODAL DLG5 DLG5 LOC108634558 LOC108634558 BMPR1A BMPR1A SEMA4D SEMA4D ENSCHIP00000000870 ENSCHIP00000000870 HAND1 HAND1 AMER1 AMER1 ACTC1 ACTC1 PPP3R1 PPP3R1 EFNA1 EFNA1 HOXA5 HOXA5 ADAM15 ADAM15 LOC102170800 LOC102170800 RTN4 RTN4 TCOF1 TCOF1 PDCD6 PDCD6 NRP1 NRP1 MESP1 MESP1 EFNB1 EFNB1 FAM172A FAM172A ACTG2 ACTG2 DLL3 DLL3 ENSCHIP00000005210 ENSCHIP00000005210 EXT1 EXT1 NOG NOG GATA4 GATA4 BMP7 BMP7 SIX2 SIX2 LOC108634559 LOC108634559 LOC108634813 LOC108634813 LAMA5 LAMA5 WNT2 WNT2 FGFR1 FGFR1 TBX20 TBX20 FLNA FLNA HAS2 HAS2 TGFBR2 TGFBR2 EDNRB EDNRB ENSCHIP00000008714 ENSCHIP00000008714 DDX5 DDX5 EDN1 EDN1 TGFB1 TGFB1 TAF10 TAF10 SIX4 SIX4 TBX3 TBX3 HAND2 HAND2 TRIM28 TRIM28 SEMA6D SEMA6D ENSCHIP00000009938 ENSCHIP00000009938 FGF10 FGF10 TMEM100 TMEM100 BMP2 BMP2 DCHS1 DCHS1 SEMA3B SEMA3B POGLUT1 POGLUT1 SEMA5A SEMA5A HEYL HEYL RBM24 RBM24 ZFP64 ZFP64 SMAD3 SMAD3 HMGA2 HMGA2 CRELD1 CRELD1 CDC42 CDC42 KLHL12 KLHL12 ERBB3 ERBB3 MSX1 MSX1 EPB41L5 EPB41L5 ENSCHIP00000012536 ENSCHIP00000012536 SFRP1 SFRP1 SNAI1 SNAI1 LOC102176871 LOC102176871 TBX2 TBX2 GATA5 GATA5 GSK3B GSK3B KBTBD8 KBTBD8 LRP6 LRP6 CUL7 CUL7 LOXL2 LOXL2 SEMA3A SEMA3A TGFBR3 TGFBR3 TCF21 TCF21 HIF1A HIF1A MEOX1 MEOX1 NRP2 NRP2 MAPK3 MAPK3 WNT5A WNT5A WNT3A WNT3A ROCK1 ROCK1 MEF2C MEF2C BCL2 BCL2 WNT16 WNT16 ANXA6 ANXA6 RDH10 RDH10 NOLC1 NOLC1 SEMA4F SEMA4F SOX8 SOX8 SCX SCX FGF8 FGF8 GBX2 GBX2 YAP1 YAP1 SEMA3C SEMA3C PHACTR4 PHACTR4 WWTR1 WWTR1 SEMA4C SEMA4C PHOX2B PHOX2B SEMA4G SEMA4G ACTA2 ACTA2 HES1 HES1 HNF1A HNF1A SEMA6A SEMA6A ENSCHIP00000019018 ENSCHIP00000019018 PEF1 PEF1 SEMA3D SEMA3D TCF15 TCF15 CDH2 CDH2 FOXF1 FOXF1 TASOR TASOR SMAD4 SMAD4 EDNRA EDNRA PTK7 PTK7 SEMA3E SEMA3E SOX10 SOX10 OSR1 OSR1 SMAD2 SMAD2 BMPR2 BMPR2 PKD2 PKD2 NOTCH4 NOTCH4 FGF9 FGF9 JAG1 JAG1 CYP26C1 CYP26C1 BMP4 BMP4 NOTCH1 NOTCH1 FOLR1 FOLR1 SEMA5B SEMA5B ENSCHIP00000023862 ENSCHIP00000023862 DDX17 DDX17 RET RET FRZB FRZB SOX9 SOX9 FN1 FN1 ZIC3 ZIC3 WNT11 WNT11 SEMA4B SEMA4B SEMA3F SEMA3F LOC108634739 LOC108634739 GSC GSC CORO1C CORO1C TGFBR1 TGFBR1 ISL1 ISL1 ACVR1 ACVR1 TGFB2 TGFB2 ZFP36L1 ZFP36L1 SEMA4A SEMA4A WNT10A WNT10A SEMA3G SEMA3G SFRP2 SFRP2 LOXL3 LOXL3 SMO SMO GDNF GDNF FAM83D FAM83D SHH SHH APLNR APLNR RANBP3L RANBP3L TBX5 TBX5 EXOC4 EXOC4 OTUD5 OTUD5 AMH AMH SNAI2 SNAI2 ENSCHIP00000029353 ENSCHIP00000029353 ENSCHIP00000029391 ENSCHIP00000029391 RADIL RADIL SIX1 SIX1 SEMA7A SEMA7A SEMA6B SEMA6B PAX1 PAX1 KITLG KITLG LEF1 LEF1 ALX1 ALX1 CTNNB1 CTNNB1 ERBB4 ERBB4 ALDH1A2 ALDH1A2 ENSCHIP00000031826 ENSCHIP00000031826 BNC2 BNC2 TEAD2 TEAD2 NUP133 NUP133 AKNA AKNA HTR2B HTR2B RFLNB RFLNB ENG ENG HEY2 HEY2 ACVRL1 ACVRL1 SEMA6C SEMA6C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108634563Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (319 aa)
ENSCHIP00000000031Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (307 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa)
ENSCHIP00000000268Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (310 aa)
NODALNodal growth differentiation factor. (346 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1946 aa)
LOC108634558Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (294 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (863 aa)
ENSCHIP00000000870Ig-like domain-containing protein. (132 aa)
HAND1Heart and neural crest derivatives expressed 1. (219 aa)
AMER1Uncharacterized protein. (1101 aa)
ACTC1Actin alpha cardiac muscle 1. (377 aa)
PPP3R1Uncharacterized protein. (170 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
HOXA5Homeobox A5. (270 aa)
ADAM15ADAM metallopeptidase domain 15. (866 aa)
LOC102170800Uncharacterized protein. (537 aa)
RTN4Reticulon. (1194 aa)
TCOF1Treacle ribosome biogenesis factor 1. (1451 aa)
PDCD6Uncharacterized protein. (185 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (256 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (373 aa)
FAM172AFamily with sequence similarity 172 member A. (416 aa)
ACTG2Actin gamma 2, smooth muscle. (376 aa)
DLL3Delta like canonical Notch ligand 3. (595 aa)
ENSCHIP00000005210Uncharacterized protein. (237 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (446 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
GATA4GATA binding protein 4. (442 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
SIX2SIX homeobox 2. (296 aa)
LOC108634559Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (324 aa)
LOC108634813Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (310 aa)
LAMA5Laminin subunit alpha 5. (2263 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
FGFR1Fibroblast growth factor receptor. (860 aa)
TBX20T-box transcription factor 20. (449 aa)
FLNAFilamin A. (2647 aa)
HAS2Uncharacterized protein. (552 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (550 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (441 aa)
ENSCHIP00000008714Uncharacterized protein. (170 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (622 aa)
EDN1Endothelin 1. (202 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
SIX4SIX homeobox 4. (784 aa)
TBX3T-box transcription factor 3. (749 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
TRIM28Tripartite motif containing 28. (837 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1073 aa)
ENSCHIP00000009938Annexin. (100 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
TMEM100Transmembrane protein 100. (134 aa)
BMP2TGF_BETA_2 domain-containing protein. (381 aa)
DCHS1Dachsous cadherin-related 1. (3258 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (773 aa)
POGLUT1Protein O-glucosyltransferase 1. (392 aa)
SEMA5ASemaphorin 5A. (1073 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
RBM24RNA binding motif protein 24. (248 aa)
ZFP64ZFP64 zinc finger protein. (680 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
HMGA2Uncharacterized protein. (104 aa)
CRELD1Cysteine rich with EGF like domains 1. (420 aa)
CDC42Uncharacterized protein. (191 aa)
KLHL12Kelch like family member 12. (568 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1344 aa)
MSX1Msh homeobox 1. (303 aa)
EPB41L5FERM domain-containing protein. (505 aa)
ENSCHIP00000012536Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (311 aa)
SFRP1Secreted frizzled related protein 1. (308 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
LOC102176871Uncharacterized protein. (921 aa)
TBX2T-box transcription factor 2. (771 aa)
GATA5GATA binding protein 5. (403 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
KBTBD8Kelch repeat and BTB domain containing 8. (601 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
CUL7Cullin 7; Belongs to the cullin family. (1698 aa)
LOXL2Lysyl oxidase like 2. (791 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (772 aa)
TGFBR3Transforming growth factor beta receptor 3. (859 aa)
TCF21Transcription factor 21. (179 aa)
HIF1AUncharacterized protein. (823 aa)
MEOX1Mesenchyme homeobox 1. (254 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (926 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
MEF2CMADS-box domain-containing protein. (441 aa)
BCL2BH4_2 domain-containing protein. (229 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
ANXA6Annexin. (689 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
NOLC1Nucleolar and coiled-body phosphoprotein 1. (678 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (764 aa)
SOX8SRY-box transcription factor 8. (534 aa)
SCXScleraxis bHLH transcription factor. (201 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
GBX2Gastrulation brain homeobox 2. (349 aa)
YAP1Yes associated protein 1. (503 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (765 aa)
PHACTR4Phosphatase and actin regulator. (714 aa)
WWTR1WW domain containing transcription regulator 1. (419 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (833 aa)
PHOX2BPaired like homeobox 2B. (315 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (844 aa)
ACTA2Actin alpha 2, smooth muscle. (377 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
HNF1AHNF1 homeobox A. (631 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1046 aa)
ENSCHIP00000019018Sec8_exocyst domain-containing protein. (413 aa)
PEF1Penta-EF-hand domain containing 1. (287 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (775 aa)
TCF15Transcription factor 15. (197 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
FOXF1Forkhead box F1. (391 aa)
TASORTranscription activation suppressor. (1631 aa)
SMAD4Mothers against decapentaplegic homolog. (513 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (775 aa)
SOX10SRY-box transcription factor 10. (469 aa)
OSR1Odd-skipped related transcription factor 1. (267 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (978 aa)
NOTCH4Notch receptor 4. (1966 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
CYP26C1Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (523 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
NOTCH1Notch receptor 1. (2508 aa)
FOLR1Folate_rec domain-containing protein. (251 aa)
SEMA5BSemaphorin 5B. (1043 aa)
ENSCHIP00000023862Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (302 aa)
DDX17DEAD-box helicase 17; Belongs to the DEAD box helicase family. (729 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1118 aa)
FRZBFrizzled related protein. (325 aa)
SOX9SRY-box transcription factor 9. (525 aa)
FN1Fibronectin 1. (2478 aa)
ZIC3Zic family member 3. (465 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (826 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (764 aa)
LOC108634739TGF_BETA_2 domain-containing protein. (197 aa)
GSCGoosecoid homeobox. (257 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (474 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
ISL1ISL LIM homeobox 1. (349 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (762 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (416 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (769 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
LOXL3Lysyl oxidase like 3. (752 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (780 aa)
GDNFGlial cell derived neurotrophic factor. (211 aa)
FAM83DFamily with sequence similarity 83 member D. (582 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
RANBP3LRAN binding protein 3 like. (466 aa)
TBX5T-box transcription factor 5. (594 aa)
EXOC4Uncharacterized protein. (408 aa)
OTUD5OTU deubiquitinase 5. (566 aa)
AMHAnti-Mullerian hormone. (575 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
ENSCHIP00000029353Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (307 aa)
ENSCHIP00000029391Uncharacterized protein. (179 aa)
RADILRap associating with DIL domain. (1068 aa)
SIX1SIX homeobox 1. (284 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (664 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (920 aa)
PAX1Paired box 1. (443 aa)
KITLGProcessed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family. (274 aa)
LEF1HMG box domain-containing protein. (430 aa)
ALX1ALX homeobox 1. (326 aa)
CTNNB1Catenin beta 1. (781 aa)
ERBB4Protein kinase domain-containing protein. (462 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa)
ENSCHIP00000031826Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (315 aa)
BNC2Basonuclin 2. (1107 aa)
TEAD2TEA domain transcription factor 2. (448 aa)
NUP133Nucleoporin 133. (1156 aa)
AKNAAT-hook transcription factor. (1431 aa)
HTR2B5-hydroxytryptamine receptor 2B. (480 aa)
RFLNBRefilin B. (216 aa)
ENGEndoglin. (649 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (964 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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