STRINGSTRING
LUZP1 LUZP1 MED12 MED12 WNT9B WNT9B ACVRL1 ACVRL1 RYR2 RYR2 CSF1 CSF1 LMO4 LMO4 LGR4 LGR4 ENSCHIP00000000097 ENSCHIP00000000097 NODAL NODAL DLG5 DLG5 TMEM59L TMEM59L MIB1 MIB1 MTHFD1 MTHFD1 HAND1 HAND1 PAK1 PAK1 STK4 STK4 TCAP TCAP GJA1 GJA1 PPP3R1 PPP3R1 HHIP HHIP HOXA5 HOXA5 SRC SRC CCDC40 CCDC40 KDR KDR DNAAF1 DNAAF1 MESP1 MESP1 SPRY2 SPRY2 GZF1 GZF1 PLXND1 PLXND1 PML PML EXT1 EXT1 NOG NOG ENSCHIP00000005724 ENSCHIP00000005724 HS3ST3A1 HS3ST3A1 BMP7 BMP7 NRARP NRARP DLG1 DLG1 ASB2 ASB2 C2CD3 C2CD3 NKX3-1 NKX3-1 ADAMTS16 ADAMTS16 GREM1 GREM1 TIMELESS TIMELESS STK3 STK3 LAMA5 LAMA5 MMP14 MMP14 TBXT TBXT TBX20 TBX20 IRX2 IRX2 COMMD5 COMMD5 GDF7 GDF7 CTSZ CTSZ TGFBR2 TGFBR2 BCL10 BCL10 CLIC4 CLIC4 EDN1 EDN1 ENSCHIP00000008875 ENSCHIP00000008875 TGFB1 TGFB1 SRF SRF VASP VASP TBX3 TBX3 SOSTDC1 SOSTDC1 HAND2 HAND2 PRICKLE1 PRICKLE1 TCTN1 TCTN1 FGF10 FGF10 CTHRC1 CTHRC1 PPP1CA PPP1CA TACSTD2 TACSTD2 BMP2 BMP2 CCL11 CCL11 DVL3 DVL3 DCHS1 DCHS1 WT1 WT1 ENSCHIP00000010686 ENSCHIP00000010686 KLHL3 KLHL3 TBX6 TBX6 SOX4 SOX4 RALA RALA ENSCHIP00000011371 ENSCHIP00000011371 TIE1 TIE1 CSNK2B CSNK2B CASP3 CASP3 SMAD3 SMAD3 PTCH1 PTCH1 RHOA RHOA BRD2 BRD2 FKBP14 FKBP14 GNA13 GNA13 ESR1 ESR1 OPA1 OPA1 SFRP1 SFRP1 TBX2 TBX2 CECR2 CECR2 RARA RARA MST1 MST1 IRX3 IRX3 LIAS LIAS BBS4 BBS4 DVL1 DVL1 MEGF8 MEGF8 GLI3 GLI3 CCDC103 CCDC103 DLL4 DLL4 FOXH1 FOXH1 ARL13B ARL13B EPHA2 EPHA2 TCF21 TCF21 HIF1A HIF1A DAG1 DAG1 NPHP3 NPHP3 AREG AREG TRAF6 TRAF6 FAT4 FAT4 HNF1B HNF1B WNT5A WNT5A WNT3A WNT3A MEF2C MEF2C BCL2 BCL2 PKD1 PKD1 RASIP1 RASIP1 PRKACA PRKACA IHH IHH RDH10 RDH10 ENSCHIP00000016739 ENSCHIP00000016739 SOX8 SOX8 BTRC BTRC FGF8 FGF8 GBX2 GBX2 YAP1 YAP1 PHB2 PHB2 PHACTR4 PHACTR4 FZD6 FZD6 SEMA4C SEMA4C ILK ILK LY6G5B LY6G5B GREB1 GREB1 GRHL2 GRHL2 LZTS2 LZTS2 CSMD2 CSMD2 IRX1 IRX1 HES1 HES1 SHANK3 SHANK3 CELSR1 CELSR1 GDF2 GDF2 HECTD1 HECTD1 LGR5 LGR5 IFT57 IFT57 TSC1 TSC1 FGF2 FGF2 SEC24B SEC24B TRIM71 TRIM71 GPC3 GPC3 SETD2 SETD2 FOXF1 FOXF1 LRP2 LRP2 GRHL3 GRHL3 WNT1 WNT1 CSMD1 CSMD1 NPNT NPNT SMAD4 SMAD4 PRKX PRKX CITED1 CITED1 SCRIB SCRIB LRP5 LRP5 SPINT2 SPINT2 ENSCHIP00000021337 ENSCHIP00000021337 EDNRA EDNRA PTK7 PTK7 PAX8 PAX8 SEMA3E SEMA3E OSR1 OSR1 KDM5B KDM5B CCM2 CCM2 PKD2 PKD2 CC2D2A CC2D2A HOXA11 HOXA11 WNK4 WNK4 EPHA7 EPHA7 DLL1 DLL1 SOX17 SOX17 LRRC1 LRRC1 NTN1 NTN1 SHROOM3 SHROOM3 KAT2A KAT2A BMP4 BMP4 NOTCH1 NOTCH1 FOLR1 FOLR1 FMN1 FMN1 FUZ FUZ RET RET STARD13 STARD13 AR AR DDR1 DDR1 SOX9 SOX9 ZIC3 ZIC3 ABL1 ABL1 WNT11 WNT11 KDM2B KDM2B HES5 HES5 SUFU SUFU PKHD1 PKHD1 EYA1 EYA1 LHX1 LHX1 IFT52 IFT52 CLUAP1 CLUAP1 NOTCH2 NOTCH2 COBL COBL SFRP2 SFRP2 SMO SMO GDNF GDNF MTSS1 MTSS1 GLMN GLMN WNT6 WNT6 FOXA1 FOXA1 FZD3 FZD3 RARG RARG SHH SHH VDR VDR MKS1 MKS1 HESX1 HESX1 LBX1 LBX1 APLNR APLNR NKX2-1 NKX2-1 CTNNBIP1 CTNNBIP1 NFATC4 NFATC4 MED1 MED1 PRKACB PRKACB HS3ST3B1 HS3ST3B1 ARHGAP35 ARHGAP35 ESRP2 ESRP2 MICAL2 MICAL2 LHX2 LHX2 DLG2 DLG2 SIX1 SIX1 MET MET EPHA4 EPHA4 GATA3 GATA3 SPINT1 SPINT1 PSEN1 PSEN1 LEF1 LEF1 AHI1 AHI1 CCDC39 CCDC39 CTNNB1 CTNNB1 DVL2 DVL2 MTHFR MTHFR CTSH CTSH GREB1L GREB1L APAF1 APAF1 TEAD2 TEAD2 KDM6A KDM6A SALL4 SALL4 SLIT2 SLIT2 HS2ST1 HS2ST1 MTHFD1L MTHFD1L KIF26B KIF26B KRAS KRAS ST14 ST14 TULP3 TULP3 RBM15 RBM15 FGF1 FGF1 ENG ENG PAX2 PAX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LUZP1Leucine zipper protein 1. (1071 aa)
MED12Med12 domain-containing protein. (2040 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
RYR2Ryanodine receptor 2. (4943 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (554 aa)
LMO4LIM domain only 4. (185 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (951 aa)
ENSCHIP00000000097Med12-PQL domain-containing protein. (315 aa)
NODALNodal growth differentiation factor. (346 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1946 aa)
TMEM59LTransmembrane protein 59 like. (349 aa)
MIB1Mindbomb E3 ubiquitin protein ligase 1. (1006 aa)
MTHFD1Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (935 aa)
HAND1Heart and neural crest derivatives expressed 1. (219 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
STK4Serine/threonine kinase 4. (487 aa)
TCAPUncharacterized protein. (167 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
PPP3R1Uncharacterized protein. (170 aa)
HHIPHedgehog interacting protein. (701 aa)
HOXA5Homeobox A5. (270 aa)
SRCTyrosine-protein kinase. (538 aa)
CCDC40Coiled-coil domain containing 40. (937 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1390 aa)
DNAAF1Dynein assembly factor 1, axonemal. (643 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (256 aa)
SPRY2Sprouty RTK signaling antagonist 2. (315 aa)
GZF1GDNF inducible zinc finger protein 1. (710 aa)
PLXND1Plexin D1. (1926 aa)
PMLPromyelocytic leukemia. (868 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (446 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
ENSCHIP00000005724Uncharacterized protein. (62 aa)
HS3ST3A1Sulfotransferase; Belongs to the sulfotransferase 1 family. (406 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
NRARPNOTCH regulated ankyrin repeat protein. (114 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (927 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (633 aa)
C2CD3C2 domain containing 3 centriole elongation regulator. (2333 aa)
NKX3-1NK3 homeobox 1. (239 aa)
ADAMTS16ADAM metallopeptidase with thrombospondin type 1 motif 16. (1279 aa)
GREM1Gremlin. (184 aa)
TIMELESSTimeless circadian regulator. (1206 aa)
STK3Serine/threonine kinase 3. (495 aa)
LAMA5Laminin subunit alpha 5. (2263 aa)
MMP14ZnMc domain-containing protein. (584 aa)
TBXTT-box transcription factor T. (435 aa)
TBX20T-box transcription factor 20. (449 aa)
IRX2Iroquois homeobox 2. (482 aa)
COMMD5COMM domain containing 5. (224 aa)
GDF7Growth differentiation factor 7. (451 aa)
CTSZCathepsin Z; Belongs to the peptidase C1 family. (304 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (550 aa)
BCL10BCL10 immune signaling adaptor. (230 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
EDN1Endothelin 1. (202 aa)
ENSCHIP00000008875BMERB domain-containing protein. (705 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SRFSerum response factor. (509 aa)
VASPVasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (383 aa)
TBX3T-box transcription factor 3. (749 aa)
SOSTDC1Sclerostin domain containing 1. (206 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
PRICKLE1Prickle planar cell polarity protein 1. (834 aa)
TCTN1Tectonic family member 1. (592 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
CTHRC1Collagen triple helix repeat containing 1. (243 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (385 aa)
TACSTD2Tumor associated calcium signal transducer 2. (315 aa)
BMP2TGF_BETA_2 domain-containing protein. (381 aa)
CCL11C-C motif chemokine. (97 aa)
DVL3Dishevelled segment polarity protein 3. (716 aa)
DCHS1Dachsous cadherin-related 1. (3258 aa)
WT1WT1 transcription factor. (450 aa)
ENSCHIP00000010686CCM2_C domain-containing protein. (440 aa)
KLHL3Kelch like family member 3. (610 aa)
TBX6T-box transcription factor 6. (437 aa)
SOX4SRY-box transcription factor 4. (504 aa)
RALARAS like proto-oncogene A. (206 aa)
ENSCHIP00000011371Uncharacterized protein. (193 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1139 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (217 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (275 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
PTCH1Patched 1. (1453 aa)
RHOARas-like protein family member A. (193 aa)
BRD2Bromodomain containing 2. (803 aa)
FKBP14Peptidylprolyl isomerase. (211 aa)
GNA13G protein subunit alpha 13. (377 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (596 aa)
OPA1OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1015 aa)
SFRP1Secreted frizzled related protein 1. (308 aa)
TBX2T-box transcription factor 2. (771 aa)
CECR2CECR2 histone acetyl-lysine reader. (1449 aa)
RARARetinoic acid receptor alpha. (462 aa)
MST1Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (722 aa)
IRX3Iroquois homeobox 3. (503 aa)
LIASLipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (372 aa)
BBS4Bardet-Biedl syndrome 4. (519 aa)
DVL1Dishevelled segment polarity protein 1. (682 aa)
MEGF8Multiple EGF like domains 8. (2836 aa)
GLI3GLI family zinc finger 3. (1614 aa)
CCDC103Coiled-coil domain containing 103. (235 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (701 aa)
FOXH1Forkhead box H1. (360 aa)
ARL13BADP ribosylation factor like GTPase 13B. (429 aa)
EPHA2EPH receptor A2. (975 aa)
TCF21Transcription factor 21. (179 aa)
HIF1AUncharacterized protein. (823 aa)
DAG1Dystroglycan 1. (895 aa)
NPHP3TPR_REGION domain-containing protein. (1325 aa)
AREGAmphiregulin. (264 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (573 aa)
FAT4FAT atypical cadherin 4. (4982 aa)
HNF1BHNF1 homeobox B. (558 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
MEF2CMADS-box domain-containing protein. (441 aa)
BCL2BH4_2 domain-containing protein. (229 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4303 aa)
RASIP1Ras interacting protein 1. (961 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (360 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
ENSCHIP00000016739BPTI/Kunitz inhibitor domain-containing protein. (267 aa)
SOX8SRY-box transcription factor 8. (534 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
GBX2Gastrulation brain homeobox 2. (349 aa)
YAP1Yes associated protein 1. (503 aa)
PHB2Prohibitin. (289 aa)
PHACTR4Phosphatase and actin regulator. (714 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (714 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (833 aa)
ILKIntegrin linked kinase. (452 aa)
LY6G5BLymphocyte antigen 6 family member G5B. (196 aa)
GREB1Uncharacterized protein. (1944 aa)
GRHL2Grainyhead like transcription factor 2. (622 aa)
LZTS2Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (672 aa)
CSMD2CUB and Sushi multiple domains 2. (3313 aa)
IRX1Iroquois homeobox 1. (475 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1704 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2710 aa)
GDF2Growth differentiation factor 2. (430 aa)
HECTD1HECT domain E3 ubiquitin protein ligase 1. (2610 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)
IFT57Intraflagellar transport 57. (429 aa)
TSC1Uncharacterized protein. (1158 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1261 aa)
TRIM71Tripartite motif containing 71. (876 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (509 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2556 aa)
FOXF1Forkhead box F1. (391 aa)
LRP2LDL receptor related protein 2. (4649 aa)
GRHL3Grainyhead like transcription factor 3. (600 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
CSMD1CUB and Sushi multiple domains 1. (3068 aa)
NPNTNephronectin. (606 aa)
SMAD4Mothers against decapentaplegic homolog. (513 aa)
PRKXUncharacterized protein; Belongs to the protein kinase superfamily. (347 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (247 aa)
SCRIBScribble planar cell polarity protein. (1582 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1615 aa)
SPINT2Serine peptidase inhibitor, Kunitz type 2. (250 aa)
ENSCHIP00000021337Uncharacterized protein. (137 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
PAX8Paired box 8. (457 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (775 aa)
OSR1Odd-skipped related transcription factor 1. (267 aa)
KDM5BLysine demethylase 5B. (1539 aa)
CCM2PID domain-containing protein. (476 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (978 aa)
CC2D2ACoiled-coil and C2 domain containing 2A. (1616 aa)
HOXA11Homeobox A11. (317 aa)
WNK4WNK lysine deficient protein kinase 4. (1235 aa)
EPHA7EPH receptor A7. (998 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa)
SOX17SRY-box transcription factor 17. (410 aa)
LRRC1Leucine rich repeat containing 1. (517 aa)
NTN1Netrin 1. (496 aa)
SHROOM3Shroom family member 3. (1989 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
NOTCH1Notch receptor 1. (2508 aa)
FOLR1Folate_rec domain-containing protein. (251 aa)
FMN1Formin 1. (1435 aa)
FUZFuzzy planar cell polarity protein. (419 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1118 aa)
STARD13StAR related lipid transfer domain containing 13. (1121 aa)
ARAndrogen receptor. (891 aa)
DDR1Tyrosine-protein kinase receptor. (915 aa)
SOX9SRY-box transcription factor 9. (525 aa)
ZIC3Zic family member 3. (465 aa)
ABL1Tyrosine-protein kinase. (1151 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
KDM2BLysine demethylase 2B. (1309 aa)
HES5Hes family bHLH transcription factor 5. (165 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (485 aa)
PKHD1PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4040 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (618 aa)
LHX1LIM homeobox 1. (406 aa)
IFT52Intraflagellar transport 52. (448 aa)
CLUAP1Clusterin associated protein 1. (438 aa)
NOTCH2Notch receptor 2. (2471 aa)
COBLCordon-bleu WH2 repeat protein. (1321 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (780 aa)
GDNFGlial cell derived neurotrophic factor. (211 aa)
MTSS1MTSS I-BAR domain containing 1. (737 aa)
GLMNGlomulin, FKBP associated protein. (592 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
FOXA1Forkhead box A1. (468 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
RARGRetinoic acid receptor gamma. (458 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
VDRVitamin D receptor. (491 aa)
MKS1MKS transition zone complex subunit 1. (645 aa)
HESX1HESX homeobox 1. (185 aa)
LBX1Ladybird homeobox 1. (281 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
NKX2-1NK2 homeobox 1. (370 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
NFATC4Nuclear factor of activated T cells 4. (901 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1577 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
HS3ST3B1Sulfotransferase; Belongs to the sulfotransferase 1 family. (388 aa)
ARHGAP35Rho GTPase activating protein 35. (1500 aa)
ESRP2Epithelial splicing regulatory protein 2. (717 aa)
MICAL2Microtubule associated monooxygenase, calponin and LIM domain containing 2. (1122 aa)
LHX2Uncharacterized protein. (422 aa)
DLG2Discs large MAGUK scaffold protein 2. (901 aa)
SIX1SIX homeobox 1. (284 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1384 aa)
EPHA4EPH receptor A4. (986 aa)
GATA3GATA binding protein 3. (467 aa)
SPINT1Serine peptidase inhibitor, Kunitz type 1. (508 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (475 aa)
LEF1HMG box domain-containing protein. (430 aa)
AHI1Abelson helper integration site 1. (1194 aa)
CCDC39Coiled-coil domain containing 39. (931 aa)
CTNNB1Catenin beta 1. (781 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
MTHFRMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (655 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (335 aa)
GREB1LGREB1 like retinoic acid receptor coactivator. (1911 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1249 aa)
TEAD2TEA domain transcription factor 2. (448 aa)
KDM6ALysine demethylase 6A. (1386 aa)
SALL4Spalt like transcription factor 4. (1063 aa)
SLIT2Slit guidance ligand 2. (1457 aa)
HS2ST1Uncharacterized protein. (356 aa)
MTHFD1LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (975 aa)
KIF26BKinesin family member 26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2112 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
ST14Suppression of tumorigenicity 14. (890 aa)
TULP3Tubby-like protein; Belongs to the TUB family. (488 aa)
RBM15RNA binding motif protein 15. (962 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
ENGEndoglin. (649 aa)
PAX2Paired box 2. (467 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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