14 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RDH10	Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
	NODAL	Nodal growth differentiation factor. (346 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	BMP7	Bone morphogenetic protein 7. (431 aa)
	HOXD13	Homeobox D13. (340 aa)
	GDF7	Growth differentiation factor 7. (451 aa)
	SOSTDC1	Sclerostin domain containing 1. (206 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	CECR2	CECR2 histone acetyl-lysine reader. (1449 aa)
	HIF1A	Uncharacterized protein. (823 aa)
	LUZP1	Leucine zipper protein 1. (1071 aa)
	TP63	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (681 aa)
	AR	Androgen receptor. (891 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	HIF1A	ENSCHIP00000024342	ENSCHIP00000014770	Androgen receptor.	Uncharacterized protein.	0.547
BMP4	BMP7	ENSCHIP00000023678	ENSCHIP00000006043	Bone morphogenetic protein 4.	Bone morphogenetic protein 7.	0.778
BMP4	FGF10	ENSCHIP00000023678	ENSCHIP00000010028	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.887
BMP4	NOG	ENSCHIP00000023678	ENSCHIP00000005264	Bone morphogenetic protein 4.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.999
BMP7	BMP4	ENSCHIP00000006043	ENSCHIP00000023678	Bone morphogenetic protein 7.	Bone morphogenetic protein 4.	0.778
BMP7	FGF10	ENSCHIP00000006043	ENSCHIP00000010028	Bone morphogenetic protein 7.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.583
BMP7	GDF7	ENSCHIP00000006043	ENSCHIP00000008087	Bone morphogenetic protein 7.	Growth differentiation factor 7.	0.918
BMP7	NOG	ENSCHIP00000006043	ENSCHIP00000005264	Bone morphogenetic protein 7.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.998
FGF10	BMP4	ENSCHIP00000010028	ENSCHIP00000023678	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 4.	0.887
FGF10	BMP7	ENSCHIP00000010028	ENSCHIP00000006043	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 7.	0.583
FGF10	HIF1A	ENSCHIP00000010028	ENSCHIP00000014770	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Uncharacterized protein.	0.436
FGF10	NOG	ENSCHIP00000010028	ENSCHIP00000005264	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.900
GDF7	BMP7	ENSCHIP00000008087	ENSCHIP00000006043	Growth differentiation factor 7.	Bone morphogenetic protein 7.	0.918
GDF7	NOG	ENSCHIP00000008087	ENSCHIP00000005264	Growth differentiation factor 7.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.975
HIF1A	AR	ENSCHIP00000014770	ENSCHIP00000024342	Uncharacterized protein.	Androgen receptor.	0.547
HIF1A	FGF10	ENSCHIP00000014770	ENSCHIP00000010028	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.436
NODAL	NOG	ENSCHIP00000000542	ENSCHIP00000005264	Nodal growth differentiation factor.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.446
NOG	BMP4	ENSCHIP00000005264	ENSCHIP00000023678	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	Bone morphogenetic protein 4.	0.999
NOG	BMP7	ENSCHIP00000005264	ENSCHIP00000006043	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	Bone morphogenetic protein 7.	0.998
NOG	FGF10	ENSCHIP00000005264	ENSCHIP00000010028	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.900